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Cellular markers of aging could reveal how insulin-producing cells begin to fail in type 2 diabetes

Diabetes researchers have puzzled for decades about why insulin-producing beta cells in one pancreatic islet often look and behave quite differently than their counterparts in the same islet or in nearby islets.

5 Apr 2017

Researchers achieve new step towards treatment of myotubular myopathy using gene therapy

A team of researchers in France, led by Dr. Ana Buj-Bello (Genethon/Inserm) and teams at the University of Washington and Harvard Medical School in the United States, achieved a new step towards the treatment of myotubular myopathy by gene therapy.

5 Apr 2017

Study shows how early-life BPA exposure leads to NAFLD in adulthood

Exposure during infancy to the common plasticizer bisphenol A "hijacks" and reprograms genes in the liver of newborn rats, leading to nonalcoholic fatty liver disease in adulthood.

2 Apr 2017

FDA approves new maintenance therapy for recurrent cancers

The U.S. Food and Drug Administration today approved Zejula (niraparib) for the maintenance treatment (intended to delay cancer growth) of adult patients with recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer, whose tumors have completely or partially shrunk (complete or partial response, respectively) in response to platinum-based chemotherapy.

27 Mar 2017

One-shot vaccine passes key preclinical test in newborn monkey models

Newborns are highly vulnerable to infections and don't respond optimally to most vaccines because their young immune systems typically mount weak antibody responses.

24 Mar 2017

FDA grants accelerated approval to new drug for treatment of rare form of skin cancer

The U.S. Food and Drug Administration today granted accelerated approval to Bavencio (avelumab) for the treatment of adults and pediatric patients 12 years and older with metastatic Merkel cell carcinoma (MCC), including those who have not received prior chemotherapy.

23 Mar 2017

Scientists identify molecule that could be targeted to prevent vision loss in diabetics and preterm infants

Researchers at Bascom Palmer Eye Institute, part of the University of Miami Miller School of Medicine, have identified a new molecule that induces the formation of abnormal blood vessels in the eyes of diabetic mice.

23 Mar 2017

Researchers find new way to expand, preserve cord-blood cells as potential treatment for Type 1 diabetes

For parents, storing their newborn baby's umbilical cord blood is a way to preserve potentially lifesaving cells. Now, a group of University of Florida Health researchers has found a way to expand and preserve certain cord-blood cells as a potential treatment for Type 1 diabetes.

22 Mar 2017

ECDC guidance aims to improve antenatal screening for infections to avoid mother-to-child transmission

Transmission of infections with HIV, hepatitis B, syphilis or rubella from mother to child before and during birth as well as in infancy still occur across Europe - despite existing prevention methods.

21 Mar 2017

New research reveals link between sickle cell trait and increased risk of developing kidney failure

New research indicates that being born with one copy of the sickle gene puts an individual at elevated risk for developing kidney failure requiring dialysis.

10 Mar 2017

Daily consumption of dairy products during pregnancy reduces risk of having low birth weight babies

A study led by the University of Granada has linked the consumption of dairy products (milk, fresh cheese, yogurt or cottage cheese) during pregnancy with a lower risk of having a low birth weight newborn.

9 Mar 2017

Many newborns not frequently assessed for continuous pain in neonatal intensive care units, study finds

In an analysis of 243 neonatal intensive care units from 18 European countries, investigators found that only 2113 of 6648 (31.8%) newborns were assessed for prolonged, continuous pain. Daily assessments of continuous pain occurred in only 10.4% of newborns.

6 Mar 2017

Neuroprotective compound could save brain cells during stroke, rat study shows

Researchers from the University of Iowa Carver College of Medicine and the University of Miami Miller School of Medicine have shown that a neuroprotective compound tested in rats provides two-pronged protection for brain cells during stroke and improves physical and cognitive outcomes in the treated animals.

2 Mar 2017

New treatment can reduce need for surgery in infants with congenital ear malformations

For infants with congenital malformations of the ear, a treatment system called EarWell can gently reshape the ear--avoiding the pain and cost of later surgery, reports a study in the March issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

28 Feb 2017

Study finding suggests new ways in which genetic mutations may cause brain disorders

Many kids say they love their mom and dad equally, but there are times when even the best prefers one parent over the other. The same can be said for how the body's cells treat our DNA instructions. It has long been thought that each copy - one inherited from mom and one from dad - is treated the same. A new study from scientists at the University of Utah School of Medicine shows that it is not uncommon for cells in the brain to preferentially activate one copy over the other.

25 Feb 2017

First breath of newborn shapes lifelong immunological milieu of lungs

The lung is an important interface between the body and the outside environment: with each breath, a surface of roughly 100 square meters exchanges oxygen for carbon dioxide. More than 10,000 liters of air pass adult lungs every day and with this come numerous viruses, bacteria and pollutants, which need to be prevented from entering the body.

22 Feb 2017

Listeria may pose severe risk of miscarriage in early stages of pregnancy

Listeria, a common food-borne bacterium, may pose a greater risk of miscarriage in the early stages of pregnancy than appreciated, according to researchers at the University of Wisconsin-Madison School of Veterinary Medicine studying how pathogens affect fetal development and change the outcome of pregnancy.

21 Feb 2017

Neonatal sepsis risk calculator reduces antibiotic use by nearly 50% in newborns

Kaiser Permanente, the largest integrated health system in the nation, led the development of a neonatal sepsis risk calculator that has safely reduced antibiotic use by nearly 50 percent in newborns, according to research published today in JAMA Pediatrics.

21 Feb 2017

Researcher finds new ways to adapt corn protein-based drug delivery method to pediatric medications

Developing medications for children can be challenging—taste and texture are important, but safety is also a major concern, according to pharmaceutical sciences professor Om Perumal at South Dakota State University.

13 Feb 2017

New study sheds light on how prenatal BPA exposure increases obesity risk

An expectant mother's exposure to the endocrine-disrupting chemical bisphenol A (BPA) can raise her offspring's risk of obesity by reducing sensitivity to a hormone responsible for controlling appetite, according to a mouse study published in the Endocrine Society's journal Endocrinology.

8 Feb 2017