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Mitochondrial mutation linked to elevated diabetes risk in Japanese men

A new study of Type 2 diabetes in Japanese populations has uncovered a previously uncharacterized genetic variant that puts male carriers at greater risk for the disease, as well as the mechanism by which it does so.

21 Jan 2021

A common genetic variant identified as risk factor for stroke

A team of Geisinger researchers has identified a common genetic variant as a risk factor for stroke, especially in patients older than 65.

19 Jan 2021

Owlstone Medical introduces breath biopsy panel for respiratory diseases

Owlstone Medical, the leader in Breath Biopsy® for applications in disease detection, today introduced the Respiratory Diseases Research Use Only Panel.

From Owlstone Medical Ltd 19 Jan 2021

Study reveals new way to target cancer’s nutritional needs

Scientists discover a way to target cancer’s nutritional needs, which could lead to a new way to treat the disease, according to a study published in Nature Communications today (Thursday).

18 Jan 2021

New tests may help improve the selection of men considering prostate cancer surveillance

Sylvester Comprehensive Cancer Center researchers are looking at ways to combine imaging and biomarkers to predict prostate cancer progression more accurately.

15 Jan 2021

Researchers use urine test to identify and verify a patient's type of asthma

In a new study, researchers at Karolinska Institutet in Sweden have used a urine test to identify and verify a patient's type of asthma.

13 Jan 2021

Scientists identify bacteria-based approach against cancer

The body's immune system is the first line of defense against infections like bacteria, viruses or cancers. Some cancers, however, have developed the art of molecular deception to avoid destruction by the body's immune system.

13 Jan 2021

Study offers data related to physicians' potential liability to use AI in personalized medicine

Physicians who follow artificial intelligence (AI) advice may be considered less liable for medical malpractice than is commonly thought, according to a new study of potential jury candidates in the U.S.

11 Jan 2021

Master Regulator proteins control cancer transcriptional identity

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the Master Regulator proteins that control the cancer's transcriptional state were virtually identical, independent of the specific genetic mutations of each patient.

11 Jan 2021

Proteogenomics can help determine effective treatment for head and neck squamous cell carcinoma

Proteogenomic analysis may offer new insight into matching cancer patients with an effective therapy for their particular cancer.

7 Jan 2021

International consortium awarded SNSF Sinergia grant to improve treatment for pediatric brain tumors

SNSF Sinergia grant awarded to research groups in Switzerland and Norway to identify novel treatment strategies for children with aggressive brain tumors.

7 Jan 2021

RNA sequencing data reveals three major molecular subtypes of Alzheimer's disease

Researchers at the Icahn School of Medicine at Mount Sinai have identified three major molecular subtypes of Alzheimer's disease (AD) using data from RNA sequencing.

7 Jan 2021

Researchers provide comprehensive molecular characterization of head and neck cancers

In what is believed to be the most comprehensive molecular characterization to date of the most common type of head and neck cancer, researchers from the Johns Hopkins departments of pathology and oncology, the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins University School of Medicine, and 18 other centers around the U.S. and Poland have clarified the contribution of key cancer-associated genes, proteins and signaling pathways in these cancers, while proposing possible new treatment avenues.

7 Jan 2021

Researchers apply AI to help physicians customize treatments for patients with oral cancers

Researchers at Case Western Reserve University and partners in the United States and India are applying the investigative and predictive capabilities of artificial intelligence (AI) to help physicians customize treatments for patients with oral squamous cell carcinomas.

5 Jan 2021

A paper-based sensor for detecting COVID-19

News-Medical talks to Dipanjan Pan about the development of a paper-based electrochemical sensor that can detect COVID-19 in less than five minutes.

5 Jan 2021

Genetic risk score can be used to determine risk of developing prostate cancer

Some racial and ethnic groups suffer relatively more often, and fare worse, from common ailments compared to others. Prostate cancer is one disease where such health disparities occur: risk for the disease is about 75 percent higher, and prostate cancer is more than twice as deadly, in Blacks compared to whites.

4 Jan 2021

Six clearly distinguishable subtypes of prediabetes identified

All prediabetes is not the same: in people in the preliminary stages of type 2 diabetes, there are six clearly distinguishable subtypes, which differ in the development of the disease, diabetes risk, and the development of secondary diseases.

4 Jan 2021

Tissue healing after brain injury could spur tumor growth

The healing process that follows a brain injury could spur tumor growth when new cells generated to replace those lost to the injury are derailed by mutations, Toronto scientists have found.

4 Jan 2021

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment

A new study led by clinician-scientists from the National Cancer Centre Singapore, with collaborators from research institutions worldwide, has found that angiosarcomas have unique genomic and immune profiles which allow them to be classified into three different subtypes.

28 Dec 2020

Polygenic risk scores from multi-population data could improve IBD predictions

Using genetic data from nearly 30,000 people, Mount Sinai researchers have built risk scores from a combination of datasets representing distinct ancestral populations that improve prediction of risk for inflammatory bowel diseases (IBD) including Crohn's disease and ulcerative colitis. The study was published in Gastroenterology on December 24.

24 Dec 2020

Precision Medicine News and Research

Mitochondrial mutation linked to elevated diabetes risk in Japanese men

A common genetic variant identified as risk factor for stroke

Owlstone Medical introduces breath biopsy panel for respiratory diseases

Study reveals new way to target cancer’s nutritional needs

New tests may help improve the selection of men considering prostate cancer surveillance

Researchers use urine test to identify and verify a patient's type of asthma

Scientists identify bacteria-based approach against cancer

Study offers data related to physicians' potential liability to use AI in personalized medicine

Master Regulator proteins control cancer transcriptional identity

Proteogenomics can help determine effective treatment for head and neck squamous cell carcinoma

International consortium awarded SNSF Sinergia grant to improve treatment for pediatric brain tumors

RNA sequencing data reveals three major molecular subtypes of Alzheimer's disease

Researchers provide comprehensive molecular characterization of head and neck cancers

Researchers apply AI to help physicians customize treatments for patients with oral cancers

A paper-based sensor for detecting COVID-19

Genetic risk score can be used to determine risk of developing prostate cancer

Six clearly distinguishable subtypes of prediabetes identified

Tissue healing after brain injury could spur tumor growth

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment

Polygenic risk scores from multi-population data could improve IBD predictions

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