SARS CoV 2 News and Research

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What are the trends in severe outcomes among patients hospitalized with COVID-19 during the first 2 years of the COVID-19 pandemic?

Researchers documented surveillance across a network of 155 acute care hospitals in Canada between March 15, 2020, and May 28, 2022.

24 Apr 2023

Study identifies an unknown SARS-CoV-2 lineage on three mink farms in Poland

Researchers detected a cryptic severe acute respiratory syndrome coronavirus 2 lineage on mink farms in Poland.

24 Apr 2023

Deciphering immunological imprinting in the context of COVID-19

In a recent article published in the journal Immunity, researchers explained the concept of immunological imprinting and its underlying principles. They also discussed its potential role in the context of coronavirus disease 2019 (COVID-19) vaccines.

24 Apr 2023

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

A self-amplifying replicon RNA vaccine against SARS-CoV-2 can elicit durable and protective immunity in pigtail macaques, even after neutralizing antibody responses have waned to undetectable levels.

23 Apr 2023

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

CMPK2 identified as a potential pan-flavivirus inhibitor, restricting virus replication and providing a basis for developing new antiviral treatments.

23 Apr 2023

An exploration of the pathophysiological factors and abnormalities of coagulation of long-COVID

Researchers explored the pathophysiological variables and coagulation abnormalities associated with long coronavirus disease (COVID).

21 Apr 2023

Antibody combination strongly protects high-risk people with early COVID-19 symptoms, trial shows

A treatment combining two antibodies against the coronavirus SARS-CoV-2 strongly protected high-risk people with early COVID-19 symptoms from hospitalization and death in an international Phase 2/3 clinical trial conducted in the first half of 2021 and co-led by researchers at Weill Cornell Medicine and NewYork-Presbyterian.

20 Apr 2023

Gestational obesity plus zika virus infection can compromise placenta’s immune response

Researchers at the University of São Paulo (USP) in Brazil have shown for the first time that gestational obesity associated with infection by zika virus influences the placenta's antiviral response, weakening the organ's capacity to attack the pathogen and protect the fetus.

20 Apr 2023

Delays in stoma reversal surgery do not affect post-operative clinical outcomes

Patients can be reassured that delays in stoma reversal surgery do not affect long-term outcomes according to research funded by Bowel Cancer UK and North West Cancer Research.

20 Apr 2023

Omicron spike N679K mutation acts as a loss-of-function mutation attenuating SARS-CoV-2 in vitro & in vivo

Researchers explored the impact of a loss-of-function mutation in the SARS-CoV-2 Omicron variants on the expression of the spike protein.

20 Apr 2023

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Researchers explored the protective systemic and mucosal immunity provided by a single dose of a live-attenuated SARS-CoV-2 vaccine candidate.

20 Apr 2023

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Researchers explored increasing replicative fitness of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants

20 Apr 2023

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Research explains how the SARS-CoV-2 virus spreads efficiently by directly infecting neighboring cells through a process called cell-to-cell transmission. The virus uses a protein called occludin (OCLN) to enter the cells and causes syncytium formation, which leads to viral spread.

20 Apr 2023

Combination of fluvoxamine and inhaled budesonide reduces severe COVID-19 in high-risk outpatients

Research reports the results of a randomized, placebo-controlled trial that investigated the effects of combining fluvoxamine and inhaled budesonide for preventing disease progression in high-risk outpatients with COVID-19. The study found that the combination treatment reduced the incidence of severe disease requiring advanced care.

20 Apr 2023

Observational cohort study of long COVID among 2 million elderly adults

Research estimates the incidence of long COVID and long Flu among Medicare patients using the World Health Organization (WHO) consensus definition. The study compares the incidence, symptomatology, and healthcare utilization between long COVID and long flu patients.

20 Apr 2023

Early use of dexamethasone associated with reduced mortality in hospitalized COVID-19 requiring breathing support

In a recent study published in the journal JAMA Network Open, researchers examined the clinical use of dexamethasone for hospitalized patients with coronavirus disease 2019 (COVID-19) respiratory illness and explored the heterogeneity of treatment outcomes across different subgroups.

19 Apr 2023

SARS CoV 2 News and Research

What are the trends in severe outcomes among patients hospitalized with COVID-19 during the first 2 years of the COVID-19 pandemic?

Study identifies an unknown SARS-CoV-2 lineage on three mink farms in Poland

Deciphering immunological imprinting in the context of COVID-19

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

An exploration of the pathophysiological factors and abnormalities of coagulation of long-COVID

Antibody combination strongly protects high-risk people with early COVID-19 symptoms, trial shows

Gestational obesity plus zika virus infection can compromise placenta’s immune response

Delays in stoma reversal surgery do not affect post-operative clinical outcomes

Omicron spike N679K mutation acts as a loss-of-function mutation attenuating SARS-CoV-2 in vitro & in vivo

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Combination of fluvoxamine and inhaled budesonide reduces severe COVID-19 in high-risk outpatients

Observational cohort study of long COVID among 2 million elderly adults

Early use of dexamethasone associated with reduced mortality in hospitalized COVID-19 requiring breathing support

Can SARS-CoV-2 infection cause diabetes?

Infectious particles of the SARS-CoV-2 virus isolated from hospital air

Next-generation vaccine strategies to combat current and emerging SARS-CoV-2 variants

Understanding the probable transmission of SARS-CoV-2 from lion to zookeepers

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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