Genes News and Research

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Genes play role in wound healing, regulate biological processes in human skin

Biologists at UC San Diego have identified eight genes never before suspected to play a role in wound healing that are called into action near the areas where wounds occur.

26 Apr 2013

Researchers discover gene that can cause 3 different diseases depending on its alteration

An international research consortium led by the Universitat Aut-noma de Barcelona (UAB), the CIBERER and the University of Wurzburg (Germany) has discovered a gene that can cause three totally different diseases, depending on how it is altered.

26 Apr 2013

Study reveals a new way for detecting colorectal cancers

A unique new study led by University of Kentucky Markey Cancer Center researchers Guo-Min Li and Libya Gu, in collaboration with Dr. Wei Yang at National Institutes of Health, reveals a novel mechanism explaining the previously unknown root cause of some forms of colorectal cancers.

26 Apr 2013

Research on miRNAs offers new therapeutic potential to fight diseases

RNA molecules, made from DNA, are best known for their role in protein production. MicroRNAs (miRNAs), however, are short (~22) nucleotide RNA sequences found in plants and animals that do not encode proteins but act in gene regulation and, in the process, impact almost all biological processes - from development to physiology to stress response.

26 Apr 2013

Research supports polygenic phenotype in schizophrenia

Cumulative genetic risk for schizophrenia has been linked to impaired prefrontal brain activity, in findings that support an additive genetic risk model for a polygenic phenotype.

25 Apr 2013

Individuals with MEN1 are at increased risk of developing neuroendocrine tumors

A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1).

25 Apr 2013

Personalized PSA testing using genetic variants reduces unnecessary prostate biopsies

With the help of genetics, prostate specific antigen screenings may become more accurate and reduce the number of unnecessary prostate biopsies, according to a new study from Northwestern Medicine.

25 Apr 2013

Hospital for Special Surgery receives grant for new genomics center to study autoimmune diseases

Hospital for Special Surgery in New York City has received a $5.6 million grant from The Tow Foundation to establish the Hospital for Special Surgery Genomics Center.

25 Apr 2013

Individual hydroxymethylcytosine molecules in DNA detected by new method involving chemical modification and nanopore analysis

Changes in the bases that make up DNA act as markers, telling a cell which genes it should read and which it shouldn’t. In the journal Angewandte Chemie, a British team has now introduced a new method that makes it possible to enrich the rare gene segments that contain the modified base hydroxymethylcytosine and to identify individual hydroxymethylcytosine molecules in DNA. Such modifications are associated with autoimmune diseases and cancer.

24 Apr 2013

Advaita selected to participate in Michigan I-Corps program starting May 2013

Advaita, a Plymouth, MI biotechnology startup company spun out from Wayne State University, is one of 25 companies selected to participate in the new Michigan I-Corps program starting May 2013.

24 Apr 2013

Study identifies gene variants associated with histological features of NAFLD

More patients could be diagnosed earlier with non-alcoholic fatty liver disease after a cohort study presented at the International Liver Congress 2013 identified variants within four genes significantly associated with the histological features of the disease.

24 Apr 2013

Investigational treatment for ALS passes early phase clinical trial for safety

An investigational treatment for an inherited form of Lou Gehrig's disease has passed an early phase clinical trial for safety, researchers at Washington University School of Medicine in St. Louis and Massachusetts General Hospital report.

24 Apr 2013

University of Leicester study investigates early detection of pancreatic cancer

Pioneering research to investigate whether pancreatic cancer can be detected early through a blood test is to be spearheaded by the University of Leicester thanks to new funding provided by Hope Against Cancer.

24 Apr 2013

Research shows sophisticated genetic circuits allow individual bacterium to act on its own

Individual freedom and social responsibility may sound like humanistic concepts, but an investigation of the genetic circuitry of bacteria suggests that even the simplest creatures can make difficult choices that strike a balance between selflessness and selfishness.

23 Apr 2013

iQBS researchers discover three unique genetic variations that influence body size, obesity in African ancestry

Researchers from Dartmouth's Institute for Quantitative Biomedical Sciences (iQBS) and the Center for Genomic Medicine have helped to discover three unique genetic variations that influence body size and obesity in men and women of African ancestry.

23 Apr 2013

Animal models of Huntington's disease allow better insights into disease's genetics

Scientific progress in Huntington's disease (HD) relies upon the availability of appropriate animal models that enable insights into the disease's genetics and/or pathophysiology.

23 Apr 2013

Researchers find deficiency in anti-tumor protein can delay DNA repair after radiation treatment

Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression of two enzymes (JMJD2b and SUV39H1) that control the folding of DNA.

23 Apr 2013

Experimental drug can reduce breast-cancer aggressiveness, restore drug-sensitivity

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) suggests that an unusual experimental drug can reduce breast-cancer aggressiveness, reverse resistance to the drug fulvestrant and perhaps improve the effectiveness of other breast-cancer drugs.

23 Apr 2013

Exposure to chemical pesticide has impacts that span multiple generations, say researchers

North Carolina State University researchers studying aquatic organisms called Daphnia have found that exposure to a chemical pesticide has impacts that span multiple generations - causing the so-called "water fleas" to produce more male offspring, and causing reproductive problems in female offspring.

23 Apr 2013

Researchers find tumors with ALK rearrangements can harbor additional mutations

The identification of potentially targetable kinase mutations has been an exciting advancement in lung cancer treatment.

23 Apr 2013

Genes News and Research

Genes play role in wound healing, regulate biological processes in human skin

Researchers discover gene that can cause 3 different diseases depending on its alteration

Study reveals a new way for detecting colorectal cancers

Research on miRNAs offers new therapeutic potential to fight diseases

Research supports polygenic phenotype in schizophrenia

Individuals with MEN1 are at increased risk of developing neuroendocrine tumors

Personalized PSA testing using genetic variants reduces unnecessary prostate biopsies

Hospital for Special Surgery receives grant for new genomics center to study autoimmune diseases

Individual hydroxymethylcytosine molecules in DNA detected by new method involving chemical modification and nanopore analysis

Advaita selected to participate in Michigan I-Corps program starting May 2013

Study identifies gene variants associated with histological features of NAFLD

Investigational treatment for ALS passes early phase clinical trial for safety

University of Leicester study investigates early detection of pancreatic cancer

Research shows sophisticated genetic circuits allow individual bacterium to act on its own

iQBS researchers discover three unique genetic variations that influence body size, obesity in African ancestry

Animal models of Huntington's disease allow better insights into disease's genetics

Researchers find deficiency in anti-tumor protein can delay DNA repair after radiation treatment

Experimental drug can reduce breast-cancer aggressiveness, restore drug-sensitivity

Exposure to chemical pesticide has impacts that span multiple generations, say researchers

Researchers find tumors with ALK rearrangements can harbor additional mutations

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