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Researchers identify potential anti-viral strategy for SARS-CoV-2 virus

In the case of an infection, the SARS-CoV-2 virus must overcome various defense mechanisms of the human body, including its non-specific or innate immune defense. During this process, infected body cells release messenger substances known as type 1 interferons. These attract natural killer cells, which kill the infected cells.

29 Jul 2020

Pilot study shows cholesterol-lowering medication improves function of coronary arteries

In a pilot study of people living with HIV or high levels of cholesterol, Johns Hopkins Medicine researchers found that a six-week course of a cholesterol-lowering medication improved the function of the coronary arteries that provide oxygen to the heart.

29 Jul 2020

Waterloo tech profiles antibodies in blood of COVID-19 patients

A world-leading University of Waterloo spinoff company, that decodes blood samples for potential treatments for illnesses like cancer and COVID-19, is expanding operations with the help of a $5-million USD investment.

29 Jul 2020

Inconsistent SARS-CoV-2 antibody results in nephrology workers

Using a broad spectrum of antibody tests the present study revealed inconsistent results for SARS-CoV-2 seroprevalence among asymptomatic individuals, while this was not the case among Covid-19 patients.

29 Jul 2020

Researchers launch randomized, placebo-controlled clinical trial of pulmozyme in COVID-19 patients

Researchers at Boston Children's Hospital and Brigham and Women's Hospital have launched a randomized, placebo-controlled clinical trial of dornase alfa (Pulmozyme) in patients with severe COVID-19 pneumonia and respiratory failure requiring mechanical ventilation.

29 Jul 2020

New method can detect small amounts of protein fragment linked to Alzheimer's disease

Researchers at Washington University School of Medicine in St. Louis have developed a technique to detect minute amounts of a protein fragment linked to Alzheimer's disease in the blood.

29 Jul 2020

Recurrent SARS-CoV-2 positives not infectious in discharged COVID-19 patients, says Chinese study

A new research paper from China published on the preprint server medRxiv* claims that recurrent positive results for SARS-CoV-2 are due to the presence of low levels of viral RNA fragments and not the shedding of infectious virus particles.

29 Jul 2020

Exciting cost-effective SARS-CoV-2 vaccine candidate using Newcastle disease

Experts warn that the world may see repeated waves of the COVID-19 pandemic. However, scientists around the world are working hard to create a protective vaccine or antiviral, which could help to reduce the number of deaths and cases the next time around.

29 Jul 2020

Basigin/CD147 discarded as an accessory SARS-CoV-2 binding receptor

By using specialized assays customized to detect specific receptor interactions, researchers from the Wellcome Sanger Institute in Cambridge UK find no evidence for direct binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to a transmembrane glycoprotein known as basigin.

28 Jul 2020

Emergent SARS-CoV-2 D614G spike mutation more infective due to "open" morphology

Researchers from the Los Alamos National Laboratory and Duke Human Vaccine Institute & Department of Surgery demonstrated that globally prevalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with the amino acid substitution D614G in the spike protein is much more infective due to profitable binding encounters with the host receptors.

28 Jul 2020

Experimental vaccine rapidly controls coronavirus in the upper and lower airways of nonhuman primates

Two doses of an experimental vaccine to prevent coronavirus disease 2019 (COVID-19) induced robust immune responses and rapidly controlled the coronavirus in the upper and lower airways of rhesus macaques exposed to SARS-CoV-2, report scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. SARS-CoV-2 is the virus that causes COVID-19.

28 Jul 2020

UMass Amherst biologists identify environmental sensing mechanism in cells

Evolutionary and developmental biologist Craig Albertson and colleagues at the University of Massachusetts Amherst report that they have identified a molecular mechanism that allows an organism to change the way it looks depending on the environment it is exposed to, a process known as phenotypic plasticity.

28 Jul 2020

Simple blood test may be a great advance for people with and at risk for Alzheimer's

A simple blood test for Alzheimer's would be a great advance for individuals with - and at risk for - the disease, families, doctors and researchers.

28 Jul 2020

A new cell-based gene therapy approach to better treat patients with hemophilia A

In a new study from the Wake Forest Institute for Regenerative Medicine researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A.

28 Jul 2020

Evolutionary origins of SARS-CoV-2 identified

By reconstructing the evolutionary history of SARS-CoV-2, the virus that is responsible for the COVID-19 pandemic, an international research team of Chinese, European and U.S. scientists has discovered that the lineage that gave rise to the virus has been circulating in bats for decades and likely includes other viruses with the ability to infect humans.

28 Jul 2020

Discovery could pave way for a blood test to diagnose Alzheimer's before symptoms appear

Two decades or more before symptoms arise, plaques of a sticky protein called amyloid begin forming in the brains of people later diagnosed with Alzheimer's disease.

28 Jul 2020

Study identifies phosphorylation-based biomarkers to guide cancer therapy

Precision medicine in cancer treatment uses genetic changes in the cancer cells to select the best therapies for individual patients.

28 Jul 2020

Scientists examine how glyphosate exposure affects reproduction

Exposure to the chemical glyphosate changed the level of some ovarian proteins in mice but did not impact ovarian steroid production, an indication glyphosate may not adversely affect reproduction, according to a new study.

28 Jul 2020

Novel drug candidate offers a major advance in the treatment for diabetes

The University of Alabama at Birmingham and Southern Research have discovered a new drug candidate that offers a major advance in the treatment for diabetes.

28 Jul 2020

Investigational drug for Alzheimer's disease may help autistic children

An extensive international study led by Prof. Illana Gozes of Tel Aviv University's Department of Human Molecular Genetics and Biochemistry found deposits of the tau protein typically found in Alzheimer's patients in tissues taken from the postmortem brain of a 7-year-old autistic child.

28 Jul 2020

Protein C News and Research

Researchers identify potential anti-viral strategy for SARS-CoV-2 virus

Pilot study shows cholesterol-lowering medication improves function of coronary arteries

Waterloo tech profiles antibodies in blood of COVID-19 patients

Inconsistent SARS-CoV-2 antibody results in nephrology workers

Researchers launch randomized, placebo-controlled clinical trial of pulmozyme in COVID-19 patients

New method can detect small amounts of protein fragment linked to Alzheimer's disease

Recurrent SARS-CoV-2 positives not infectious in discharged COVID-19 patients, says Chinese study

Exciting cost-effective SARS-CoV-2 vaccine candidate using Newcastle disease

Basigin/CD147 discarded as an accessory SARS-CoV-2 binding receptor

Emergent SARS-CoV-2 D614G spike mutation more infective due to "open" morphology

Experimental vaccine rapidly controls coronavirus in the upper and lower airways of nonhuman primates

UMass Amherst biologists identify environmental sensing mechanism in cells

Simple blood test may be a great advance for people with and at risk for Alzheimer's

A new cell-based gene therapy approach to better treat patients with hemophilia A

Evolutionary origins of SARS-CoV-2 identified

Discovery could pave way for a blood test to diagnose Alzheimer's before symptoms appear

Study identifies phosphorylation-based biomarkers to guide cancer therapy

Scientists examine how glyphosate exposure affects reproduction

Novel drug candidate offers a major advance in the treatment for diabetes

Investigational drug for Alzheimer's disease may help autistic children

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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