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Study shows both IDH-mutant WHO-defined molecular subgroups could benefit from PCV chemoradiotherapy

A recent, updated predictive analysis of the three WHO-defined molecular subgroups based on isocitrate dehydrogenase 1/2 (IDH) mutation status and 1p/19q co-deletion status represented in the high-risk treatment arms of the NRG Oncology clinical trial NRG-RTOG 9802 indicates that both IDH-mutant sub-groups (IDHmut-noncodel and IDHmut-codel) could benefit from the addition of PCV chemotherapy to radiotherapy treatment.

3 Jun 2019

Targeted breast cancer therapy shows 'encouraging' results

Researchers have developed a targeted therapy that may significantly increase the survival of pre-menopausal women with advanced breast cancer

3 Jun 2019

Combination immunotherapy shows promise in pre-surgical setting for early-stage lung cancers

Neoadjuvant, or pre-surgical, treatment with nivolumab plus ipilimumab resulted in an overall major pathologic response rate of 33 percent of treated patients with early-stage, resectable non-small cell lung cancers, meaning these patients had less than or equal to 10 percent viable tumor remaining at surgery.

3 Jun 2019

Researchers develop new method to reduce toxicity of gluten for people with celiac disease

A team of researchers from Universidad Politécnica de Madrid and Universidade de Trás-os-Montes e Alto Douro along with other research institutions have developed a method that will allow us to reduce the toxicity of gluten for people who suffer from celiac disease.

3 Jun 2019

Georgetown University Medical Center announces launch of clinical trial for Lewy body dementia

Georgetown University Medical Center announces the launch of the only known therapeutic (disease modifying) clinical trial for Lewy body dementia, a neurological disorder that affects a million people in the United States for which there are no approved medications that modify the disease.

3 Jun 2019

People living with HIV have increased risk for heart diseases and face health challenges

Effective antiretroviral therapy has changed the human immunodeficiency virus (HIV) from a progressive, fatal disease to a chronic, manageable condition that is associated with higher rates of heart attacks, strokes, heart failure, sudden cardiac deaths, and other diseases compared to people without HIV, according to a new scientific statement from the American Heart Association published in the Association journal Circulation.

3 Jun 2019

International clinical study of new drug to treat advanced prostate cancers yields promising results

Today the New England Journal of Medicine published the first results of a phase III international clinical study called TITAN (National Clinical Trials Number 02489318), which evaluated the effectiveness and safety of a new drug, apalutamide, to treat advanced prostate cancers.

3 Jun 2019

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Adding the targeted therapy ribociclib to hormone therapy significantly improved overall survival (OS) in premenopausal patients with advanced hormone receptor-positive (HR+) breast cancer, according to results of the MONALEESA-7 Phase III clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

3 Jun 2019

Oral androgen receptor inhibitor improves outcomes for men with mHSPC

Enzalutamide, an oral androgen receptor inhibitor, can improve outcomes for men with metastatic hormone-sensitive prostate cancer, according to a large study presented by Christopher Sweeney, MBBS of Dana-Farber Cancer Institute's Lank Center for Genitourinary Oncology, during the American Society of Clinical Oncology Annual Meeting.

3 Jun 2019

Drug therapy may delay onset of myeloma symptoms, finds study

The largest randomized trial involving smoldering multiple myeloma suggests that lenalidomide, a cancer drug, may delay the onset of myeloma symptoms, according to Mayo Clinic researchers.

3 Jun 2019

Body's endocannabinoid system appears to be new target for drug development against OCD

The body's endocannabinoid system, due to the critical role it plays in regulating neurotransmitter signaling, is an enticing target for drug development against disorders associated with anxiety, stress, and repetitive behaviors, such as obsessive-compulsive disorder.

3 Jun 2019

New targeted therapy using radio waves blocks growth of liver cancer cells, study shows

A new targeted therapy using non-thermal radio waves has been shown to block the growth of liver cancer cells anywhere in the body without damaging healthy cells, according to a study conducted by scientists at Wake Forest School of Medicine, part of Wake Forest Baptist Health.

31 May 2019

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

For patients with operable non-small cell lung cancer, pre-surgical "neoadjuvant" treatment with an immune checkpoint inhibitor was well tolerated and, in many cases, caused significant tumor cell death in a large, multicenter clinical trial involving investigators at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and nine other research centers

31 May 2019

IDT releases new ultra-high performance CRISPR Cas12a enzyme

As an advocate for the needs of researchers working at the forefronts of genomic research, Integrated DNA Technologies releases its latest CRISPR enzyme Alt-R® Cas12a Ultra.

From Integrated DNA Technologies 31 May 2019

Study aims to understand role of immune cells in the development of macular scarring

A study funded by research charity Fight for Sight aims to understand the role that our own immune cells play in the development of macular scarring.

31 May 2019

Blood stem cell breakthrough could spare some patients from side effects of cancer treatments

A method of growing blood stem cells in the laboratory has been developed by researchers at Stanford University and the University of Tokyo, in a breakthrough that could spare some people with blood and immune disorders from the side effects of intensive chemotherapy and radiotherapy.

31 May 2019

Study highlights the need to educate oncologists about molecular profiling

A questionnaire aimed at assessing how well community oncologists understand "molecular profiling" results from tumor specimens found that 69 percent of participants either said they don't know the answers, or they responded incorrectly.

31 May 2019

IU researchers, collaborators receive grant to develop immunotherapy treatments for cancer

A team of researchers from Indiana University and Memorial Sloan Kettering Cancer Center have been awarded a $4.1 million National Cancer Institute "Cancer Moonshot" grant to develop immunotherapy treatments for cancer in children and adolescents, especially those with leukemia.

31 May 2019

Dyson-Hudson receives grant to study effectiveness of new treatment for shoulder pain

Trevor Dyson-Hudson, MD, director of the Center for Spinal Cord Injury Research at Kessler Foundation, was awarded a $549,000 grant by the New Jersey Commission on Spinal Cord Research.

31 May 2019

Researchers unveil clues into how breast cancer cells spread around the body

Researchers have unveiled clues into how breast cancer cells spread around the body.

31 May 2019

Therapy News and Research

Study shows both IDH-mutant WHO-defined molecular subgroups could benefit from PCV chemoradiotherapy

Targeted breast cancer therapy shows 'encouraging' results

Combination immunotherapy shows promise in pre-surgical setting for early-stage lung cancers

Researchers develop new method to reduce toxicity of gluten for people with celiac disease

Georgetown University Medical Center announces launch of clinical trial for Lewy body dementia

People living with HIV have increased risk for heart diseases and face health challenges

International clinical study of new drug to treat advanced prostate cancers yields promising results

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Oral androgen receptor inhibitor improves outcomes for men with mHSPC

Drug therapy may delay onset of myeloma symptoms, finds study

Body's endocannabinoid system appears to be new target for drug development against OCD

New targeted therapy using radio waves blocks growth of liver cancer cells, study shows

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

IDT releases new ultra-high performance CRISPR Cas12a enzyme

Study aims to understand role of immune cells in the development of macular scarring

Blood stem cell breakthrough could spare some patients from side effects of cancer treatments

Study highlights the need to educate oncologists about molecular profiling

IU researchers, collaborators receive grant to develop immunotherapy treatments for cancer

Dyson-Hudson receives grant to study effectiveness of new treatment for shoulder pain

Researchers unveil clues into how breast cancer cells spread around the body

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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