Cell Proliferation News and Research

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Cell therapies for diabetes, cancer

Therapies using stem cell transplants are advancing promising treatments for such conditions as Alzheimer's Disease, neurological diseases and spinal cord injury, and heart disease.

20 Mar 2008

Discovery of new mechanism involved in inflammatory diseases

Investigators at Hospital for Special Surgery have identified a new mechanism involved in the pathogenesis of inflammatory diseases such as rheumatoid arthritis.

17 Mar 2008

Cell therapy for rejuvenating aged brain by injection of human umbilical cord blood

When human umbilical cord blood cells (UCBC) were injected into aged laboratory animals, researchers at the University of South Florida (USF) found improvements in the microenvironment of the hippocampus region of the animals' brains and a subsequent rejuvenation of neural stem/progenitor cells.

11 Mar 2008

Artificial 'cells' that boost the immune response to cancer

Using artificial cell-like particles, Yale biomedical engineers have devised a rapid and efficient way to produce a 45-fold enhancement of T cell activation and expansion, an immune response important for a patient's ability to fight cancer and infectious diseases, according to an advance on line report in Molecular Therapy.

27 Feb 2008

Newly discovered ERK pathway proteins related to CagA induced disease

Cytotoxin-associated gene A protein (CagA) from type I H.pylori has been proved by epidemiological and experimental studies to be closely associated with the H.pylori induced gastric diseases, especially gastric cancer.

25 Feb 2008

Researchers use embryonic stem cells to develop functioning immune system blood cells

For the first time, researchers have used embryonic stem cells to develop functioning immune system blood cells -- an important step in eventually using embryonic stem cells as an alternative source of cells for traditional bone marrow transplantations.

14 Feb 2008

Discovery that embryonic stem cells can be used to create functional immune system blood cells

A new study demonstrates for the first time that embryonic stem cells can be used to create functional immune system blood cells, a finding which is an important step in the utilization of embryonic stem cells as an alternative source of cells for bone marrow transplantation.

13 Feb 2008

Toxic blue-green algae may provide new anti-cancer drugs

A collaborative team of researchers spearheaded by Dennis Carson M.D., professor of medicine and director of the Rebecca and John Moores UCSD Cancer Center at the University of California, San Diego (UCSD) has identified a potent new anti-cancer drug isolated from a toxic blue-green algae found in the South Pacific.

12 Feb 2008

Natural secretion marks difference between mole and melanoma

A protein naturally produced and secreted by the body can make the difference between your average mole and melanoma, which killed more than 8,000 people in the United States last year, reveals a new study in the February 8 issue of the journal Cell, a publication of Cell Press.

8 Feb 2008

Vitamin D for cancer

It sounds too good to be true … a little inexpensive pill that could block the development of some cancers, strengthen bones, prevent multiple sclerosis and alleviate winter depression.

7 Feb 2008

Acanthus ilicifolius plant may combat liver cancer

Liver cancer is the fifth most common cancer in the world with a poor prognosis. About three quarters of the cases of liver cancer are found in Southeast Asia, including China, Hong Kong, Taiwan, Korea, India, and Japan.

17 Jan 2008

Research may improve prognosis and treatment of lung cancer

A group of scientists led by Professor Xavier Pares of the Department of Biochemistry and Molecular Biology at Universitat Autonoma de Barcelona, has published a research on AKR1B10, an enzyme that is detected in large quantities only in lung cancers, particularly those caused by smoking.

8 Jan 2008

Agent orange chemical, dioxin, attacks the mitochondria to cause cancer

Researchers with the University of Pennsylvania School of Veterinary Medicine have demonstrated the process by which the cancer-causing chemical dioxin attacks the cellular machinery, disrupts normal cellular function and ultimately promotes tumor progression.

18 Dec 2007

Why the switch stays on

Cellular processes, such as when to multiply, are often regulated by switches that control the frequency and timing of interactions between proteins.

13 Dec 2007

Closest look ever at native human tissue

Seeing proteins in their natural environment and interactions inside cells has been a long-standing goal.

5 Dec 2007

Wyeth receives European approval for TORISEL

Wyeth Pharmaceuticals, a division of Wyeth, has announced that the European Commission has approved TORISEL (temsirolimus) for the first-line treatment of patients with advanced renal cell carcinoma (RCC) who have at least three of six prognostic risk factors. TORISEL is the only approved cancer therapy that specifically inhibits the mTOR (mammalian target of rapamycin) kinase, an important regulator of cell proliferation, cell growth and cell survival.

27 Nov 2007

New technique enables the detection of biomolecules' dynamic reactions in a single living cell

By taking advantage of the signature frequency by which organic and inorganic molecules absorb light, the team of researchers, led by Luke Lee, professor of bioengineering and director of UC Berkeley's Biomolecular Nanotechnology Center, can determine in real time whether specific enzymes are activated or particular genes are expressed, all with unprecedented resolution within a single living cell.

19 Nov 2007

New insight into how cystatin C may lower the risk for Alzheimer's disease

For unknown reasons a protein called amyloid beta aggregates into toxic plaques in the brain, killing neurons.

19 Nov 2007

Compound of milk thistle shows anti-cancer effects

Recently, scientists demonstrated the anti-cancer effects of silibinin, a major biologically active compound of milk thistle. Being widely used as a folk remedy for liver diseases, milk thistle is safe and well-tolerated, and it protects the liver from drug or alcohol-related injury.

15 Nov 2007

Telomerase enzyme structure provides significant new target for anti-cancer therapies

Inappropriate activation of a single enzyme, telomerase, is associated with the uncontrollable proliferation of cells seen in as many as 90 percent of all of human cancers. Since the mid-1990s, when telomerase was first identified in human tumors, scientists have eyed the enzyme as an ideal target for developing broadly effective anti-cancer drugs.

14 Nov 2007