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Enamine contributes to the discovery of promising broad-spectrum coronavirus antiviral

Enamine, a leading chemistry and R&D services company, today announced that it was a key synthetic chemistry contributor to a first-of-its-kind, open-science approach that led to the development of a promising broad-spectrum coronavirus antiviral pre-clinical candidate.

23 Oct 2025

Novel molecule found to be a key player in kidney injury and repair

Chronic kidney disease (CKD) is a progressive condition in which the kidneys gradually lose their ability to filter waste from the blood.

23 Oct 2025

A new way to monitor chemotherapy drug behavior inside cells

Scientists have made incredible progress in developing cancer therapies that help patients across cancer types.

22 Oct 2025

New study solves lung transplant rejection mystery

More than 50% of lung-transplant recipients experience a rejection of their new lung within five years of receiving it, yet the reason why this is such a prevalent complication has remained a medical mystery.

22 Oct 2025

Rare case of pancreatic Hodgkin lymphoma is often misdiagnosed as pancreatic adenocarcinoma

A new case report was published in Volume 12 of Oncoscience on October 6, 2025, titled "A peculiar case of primary lymphoma of pancreas: A rare presentation of Hodgkin lymphoma."

22 Oct 2025

Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs).

22 Oct 2025

Study forces a textbook rewrite on cell division

Scientists at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed to act as a motor dragging chromosomes into place during cell division, in fact plays a completely different role in chromosome movement.

22 Oct 2025

Analysis highlights the differing physical side effects of antidepressants

Antidepressants can differ widely in how they physically affect the body, including around a 4 kg difference in weight change between certain drugs (approximately 2.5 kg weight loss from agomelatine and 2kg weight gain from maprotiline), confirms a systematic review and meta-analysis published in The Lancet.

22 Oct 2025

Updated CPR guidelines provide expanded recommendations for managing choking and opioid overdose

The "2025 American Heart Association Guidelines for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care (ECC)," published today in the Association's flagship journal, Circulation, marks the first full revision of lifesaving resuscitation guidance since 2020.

22 Oct 2025

New drug combination shows promise in treating colorectal cancer

Colorectal cancer is one of the most common tumors among people over the age of 50. Although it is known to develop from small lesions or polyps, its exact causes are unknown — only a few risk factors are known — and it is usually treated with surgery, chemotherapy and radiotherapy, or biological therapies.

22 Oct 2025

Prescription drug advertising proves more effective in reducing smoking rates

A new peer-reviewed study in the INFORMS journal Marketing Science finds that direct-to-consumer (DTC) advertising for prescription smoking-cessation drugs meaningfully reduces cigarette use. At the same time, the research found that advertising for over the counter (OTC) nicotine products does not reduce cigarette use.

22 Oct 2025

A new car vs. health insurance? Average family job-based coverage hits $27K

With the federal shutdown entering its fourth week, spurred by a stalemate over the cost of health insurance for 22 million Americans on Affordable Care Act plans, a new report shows that over 154 million people with coverage through an employer also face steep price hikes — and that the situation is likely to get worse.

22 Oct 2025

Discovery offers a breakthrough approach to combat prostate tumor growth

Prostate cancer relies on genetic "switches", called enhancers, that can turn on tumor-promoting genes.

22 Oct 2025

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Researchers provide a comprehensive overview of the blood-brain barrier (BBB), detailing its cellular architecture, transport mechanisms, and role in protecting the brain from toxins. The paper highlights how BBB dysfunction contributes to neurological diseases and explores emerging technologies to overcome drug delivery challenges.

21 Oct 2025

New study offers hope for patients with treatment-resistant focal epilepsy

About one-third of patients with focal epilepsy, a common form of the neurological disorder, are believed to respond poorly to available therapies.

21 Oct 2025

Study provides a new approach for the treatment of prostate tumors

An international research team led by the Medical University of Vienna has demonstrated for the first time that thyroid hormone plays a key role in the development and progression of prostate cancer.

21 Oct 2025

Largest trial of adjuvant pembrolizumab in Merkel cell carcinoma reports key benefit

A new cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) shows that a drug that utilizes the body's immune system to target and eliminate cancer cells appeared to reduce the risk of distant metastases for an aggressive form of skin cancer when given immediately after surgery, but did not significantly reduce the overall risk of recurrence, which was a co-primary endpoint of the trial.

21 Oct 2025

Researchers engineer a tool to dismantle cancer's RNA-built growth hubs

In a city, coworking hubs bring people and ideas together. Inside cancer cells, similar hubs form-but instead of fueling progress, they supercharge disease. That's what researchers at the Texas A&M University Health Science Center (Texas A&M Health) have discovered inside the cells of a rare and aggressive kidney cancer.

21 Oct 2025

Study reveals protein plaques in neurodegeneration function as enzymes, breaking down ATP

A new study led by Rice University's Pernilla Wittung-Stafshede has revealed that protein clumps, or plaques that clog the brain, associated with Parkinson's disease are not merely waste; they can actively drain energy from brain cells.

21 Oct 2025

New drug testing analyzer from Siemens Healthineers raises the bar for court, military, and forensics testing, offering clinical-quality results

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From Siemens Healthineers 20 Oct 2025

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Drugs News and Research

Enamine contributes to the discovery of promising broad-spectrum coronavirus antiviral

Novel molecule found to be a key player in kidney injury and repair

A new way to monitor chemotherapy drug behavior inside cells

New study solves lung transplant rejection mystery

Rare case of pancreatic Hodgkin lymphoma is often misdiagnosed as pancreatic adenocarcinoma

Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

Study forces a textbook rewrite on cell division

Analysis highlights the differing physical side effects of antidepressants

Updated CPR guidelines provide expanded recommendations for managing choking and opioid overdose

New drug combination shows promise in treating colorectal cancer

Prescription drug advertising proves more effective in reducing smoking rates

A new car vs. health insurance? Average family job-based coverage hits $27K

Discovery offers a breakthrough approach to combat prostate tumor growth

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

New study offers hope for patients with treatment-resistant focal epilepsy

Study provides a new approach for the treatment of prostate tumors

Largest trial of adjuvant pembrolizumab in Merkel cell carcinoma reports key benefit

Researchers engineer a tool to dismantle cancer's RNA-built growth hubs

Study reveals protein plaques in neurodegeneration function as enzymes, breaking down ATP

New drug testing analyzer from Siemens Healthineers raises the bar for court, military, and forensics testing, offering clinical-quality results

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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