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First Edition: February 21, 2014

Today's headlines include reports checking the status of different state health exchanges as well as efforts to expand Medicaid.

21 Feb 2014

New DNA Quantification kits may help scientists to quickly assess highly compromised human DNA

Forensic scientists can now more quickly assess the quantity and quality of human DNA in highly compromised and degraded casework samples and provide the critical information needed to drive informed decisions on subsequent steps in the analysis process, thanks to two new Life Technologies quantification solutions announced today by Thermo Fisher Scientific.

21 Feb 2014

The Future of DNA Sequencing

In this interview, Barret Bready discusses the current gold standards in DNA sequencing and how the Nabsys platform is revolutionizing this process.

18 Feb 2014

Study shows how Bcl-2 cancer-related protein signals cancer cells to live longer

A team of researchers from Case Western Reserve School of Medicine has discovered how the cancer-related protein Bcl-2 signals cancer cells to live longer.

14 Feb 2014

Scientists identify network of genes that controls human brain activity, memory and schizophrenia

Many psychiatric disorders are accompanied by memory deficits. Basel scientists have now identified a network of genes that controls fundamental properties of neurons and is important for human brain activity, memory and the development of schizophrenia.

14 Feb 2014

Calcivis Caries Activity Imaging System receives CE Mark in Europe

Calcivis, a medical devices company focused on revolutionising the management of tooth decay, today announces that its Calcivis Caries Activity Imaging System has been granted a CE Mark in Europe. A CE Mark is required before a medical device can be marketed in the EU and a number of other countries and signifies that the manufacturer meets the requirements of European legislation.

12 Feb 2014

Gilead submits NDA to FDA for fixed-dose combination of ledipasvir and sofosbuvir for hepatitis C infection

Gilead Sciences, Inc. (Nasdaq: GILD) today announced that the company has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for a once-daily fixed-dose combination of the NS5A inhibitor ledipasvir (LDV) 90 mg and the nucleotide analog polymerase inhibitor sofosbuvir (SOF) 400 mg for the treatment of chronic hepatitis C genotype 1 infection in adults.

11 Feb 2014

Researchers shed new light on pain associated with bacterial infections

Components in the outer wall of bacteria directly activate pain sensors, triggering immediate pain and inflammatory responses. This finding by a multinational team of researchers led by Professor Karel Talavera (KU Leuven, Belgium) and Professor Félix Viana (Institute of Neuroscience, Spain) sheds new light on pain associated with bacterial infections and reveals a new target for drugs designed to treat them.

11 Feb 2014

Optogenetics technique allows scientists to control neurons' electrical activity

Optogenetics is a technique that allows scientists to control neurons' electrical activity with light by engineering them to express light-sensitive proteins. Within the past decade, it has become a very powerful tool for discovering the functions of different types of cells in the brain.

10 Feb 2014

Researchers develop multifunctional nanoparticle to pinpoint blood vessel plaques

A team of researchers, led by scientists at Case Western Reserve University, has developed a multifunctional nanoparticle that enables magnetic resonance imaging (MRI) to pinpoint blood vessel plaques caused by atherosclerosis.

7 Feb 2014

Rare and de novo mutations flesh out schizophrenia picture

Two studies in Nature show that rare disruptive and de novo mutations may contribute to the pathophysiology of schizophrenia.

6 Feb 2014

Researchers identify how mutated protein can cause high blood pressure

Researchers from the University of Southern Denmark have identified how a mutated protein can lead to holes in a protein sitting in a cell's membrane. Such holes cause high blood pressure, and the discovery can now lead to new and better medication for high blood pressure.

28 Jan 2014

Interplanetary dust particles could deliver water and organics to the Earth, say scientists

Researchers from the University of Hawaii - Manoa (UHM) School of Ocean and Earth Science and Technology (SOEST), Lawrence Livermore National Laboratory, Lawrence Berkeley National Laboratory, and University of California - Berkeley discovered that interplanetary dust particles (IDPs) could deliver water and organics to the Earth and other terrestrial planets.

25 Jan 2014

Researchers suggest possible novel target for seizure-blocking medicines

Researchers in the biomedical engineering department at Case Western Reserve University have found that epileptic activity can spread through a part of the brain in a new way, suggesting a possible novel target for seizure-blocking medicines.

24 Jan 2014

Scientists figure out key step in how free calcium is controlled in the body

Scientists at Johns Hopkins report they have figured out a key step in how "free" calcium - the kind not contained in bones - is managed in the body, a finding that could aid in the development of new treatments for a variety of neurological disorders that include Parkinson's disease.

24 Jan 2014

Johns Hopkins researchers reveal how calcium is controlled in the body

Scientists at Johns Hopkins report they have figured out a key step in how “free” calcium — the kind not contained in bones — is managed in the body, a finding that could aid in the development of new treatments for a variety of neurological disorders that include Parkinson’s disease.

24 Jan 2014

Rice University scientists create new technique to widen bottleneck for pharmaceutical, other industries

Rice University scientists have created a way to fine tune a process critical to the pharmaceutical industry that could save a lot of time and money.

23 Jan 2014

NCCC physicians use new gene sequencing equipment for testing abnormal DNA in cancerous tumor cells

Clinical laboratory experts and physicians at Dartmouth-Hitchcock Norris Cotton Cancer Center (NCCC) achieved 100 percent accuracy in testing for abnormal DNA in cancerous tumor cells with its new gene sequencing equipment and panels.

23 Jan 2014

Scientists identify channel that acts as 'brake', limiting spontaneous pain

Scientists have identified a channel present in many pain detecting sensory neurons that acts as a 'brake', limiting spontaneous pain. It is hoped that the new research, published today [22 January] in the Journal of Neuroscience, will ultimately contribute to new pain relief treatments.

22 Jan 2014

Researchers find new candidate that may help combat malaria

Two of the most urgent challenges for scientists are the battles against food shortages and infectious diseases like malaria. Unfortunately, both the herbicides used to protect plants and the anti-infectives that shield us from disease rapidly lose their effectiveness as the target organisms develop resistance. In order to benefit both fields at once, scientists tested lead compounds from agrochemical research against infectious germs as well.

21 Jan 2014

Ion News and Research

First Edition: February 21, 2014

New DNA Quantification kits may help scientists to quickly assess highly compromised human DNA

The Future of DNA Sequencing

Study shows how Bcl-2 cancer-related protein signals cancer cells to live longer

Scientists identify network of genes that controls human brain activity, memory and schizophrenia

Calcivis Caries Activity Imaging System receives CE Mark in Europe

Gilead submits NDA to FDA for fixed-dose combination of ledipasvir and sofosbuvir for hepatitis C infection

Researchers shed new light on pain associated with bacterial infections

Optogenetics technique allows scientists to control neurons' electrical activity

Researchers develop multifunctional nanoparticle to pinpoint blood vessel plaques

Rare and de novo mutations flesh out schizophrenia picture

Researchers identify how mutated protein can cause high blood pressure

Interplanetary dust particles could deliver water and organics to the Earth, say scientists

Researchers suggest possible novel target for seizure-blocking medicines

Scientists figure out key step in how free calcium is controlled in the body

Johns Hopkins researchers reveal how calcium is controlled in the body

Rice University scientists create new technique to widen bottleneck for pharmaceutical, other industries

NCCC physicians use new gene sequencing equipment for testing abnormal DNA in cancerous tumor cells

Scientists identify channel that acts as 'brake', limiting spontaneous pain

Researchers find new candidate that may help combat malaria

Enhancing confidence in chemical ionization spectrometry data eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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