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Tumor suppressor gene PTEN may be potential Achilles heel for breast cancer cells

In an article published July 17, 2018 by Nature Communications, a highly collaborative team of researchers at the Medical University of South Carolina and Ohio State University report that normal breast cells can prevent successful radiation treatment of breast cancer due to dysregulation between tumor suppressors and oncogenes.

2 Aug 2018

How rival opioid makers sought to cash in on alarm over oxycontin’s dangers

As Purdue Pharma faced mounting criticism over deaths linked to OxyContin, rival drugmakers saw a chance to boost sales by stepping up marketing of similarly dangerous painkillers, such as fentanyl, morphine and methadone, Purdue internal documents reveal.

2 Aug 2018

Researchers discover key piece for slowing colorectal cancer subtype

Inhibiting the Jagged 1 protein in mice prevents the proliferation and growth of colon and rectal tumors. What is more, this approach to the disease permits the removal of existing tumors.

2 Aug 2018

Microscopic imaging helps better understand cancer bone metastasis

Scientists at The University of Texas MD Anderson Cancer Center have engineered a system allowing microscopic monitoring and imaging of cancer that has spread to the bone in mice so they can better understand and develop treatment for bone metastasis in humans.

2 Aug 2018

Janssen’s Darzalex receives positive CHMP opinion for treating multiple myeloma patients

The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended broadening the existing marketing authorization for Darzalex® for use as frontline therapy.

28 Jul 2018

New approach shows important role of microRNAs in papillomavirus life cycle

The discovery of microRNAs encoded by papillomaviruses supports the important role of these small molecules in persistent infection, according to a study published July 26 in the open-access journal PLOS Pathogens.

27 Jul 2018

CNDA approves KEYTRUDA for treatment of advanced melanoma

Merck, known as MSD outside the United States and Canada, today announced that KEYTRUDA, Merck's anti-PD-1 therapy, has been approved by the China National Drug Administration for the treatment of adult patients with unresectable or metastatic melanoma following failure of one prior line of therapy.

26 Jul 2018

MicroRNA panel could categorize indeterminate thyroid nodule samples into malignant and benign

A panel of 19 microRNAs identified using next-generation sequencing could categorize indeterminate thyroid nodule samples into malignant and benign.

26 Jul 2018

Anti-cancer gene may switch side and promote cancer growth, shows study

It doesn't often happen that army generals switch sides in the middle of a war, but when cancer's attack is underway, it may even cause a gene that acts as the body's master defender to change allegiance.

26 Jul 2018

New control system regulates morphology, orientation of cells constituting animal tissues

A collaborative research group led by Kumamoto University has developed a new control system for regulating the morphology and orientation of cells that constitute animal tissues.

25 Jul 2018

Turmeric derivative could be used in eye drops to treat early stages of glaucoma

A derivative of turmeric could be used in eye drops to treat the early stages of glaucoma, finds a new study led by UCL and Imperial College London researchers.

24 Jul 2018

Patients with colon cancers on the right side have worse survival rates than those with left-sided tumors

Patients with colorectal cancer tumors on the right side may have poorer five-year survival rates than those whose tumors are located on the left side.

24 Jul 2018

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

The U.S. Food and Drug Administration today approved Tibsovo (ivosidenib) tablets for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) who have a specific genetic mutation.

20 Jul 2018

Researchers develop new way to uncover hidden breast cancer tumors

Breast cancer is the most common form of cancer among women, accounting for 25 % of all cancer cases worldwide.

20 Jul 2018

New strategy may lead to more accurate breast cancer diagnoses

A study in Molecular Oncology indicates that examining the protein and RNA in leftover materials from routine diagnostic tests for breast cancer may lead to more accurate diagnoses.

18 Jul 2018

CT scans may raise brain tumor risk

A new study in the Journal of the National Cancer Institute suggests that CT scans, commonly used in medical imaging, may increase the risk of brain tumors.

18 Jul 2018

Researchers reduce size of tumors in mice by artificially activating the brain's reward system

By artificially activating the brain's reward system, researchers at the Technion-Israel Institute of Technology have dramatically reduced the size of cancerous tumors in mice. The findings were published recently in the journal Nature Communications.

16 Jul 2018

Managing multiple ipsilateral breast cancer with potential new surgical options

A new multi-institutional clinical trial compared outcomes of women with multiple ipsilateral breast cancer, or more than one site of disease in the same breast, who underwent breast-conserving surgery, with outcomes of those who converted to mastectomy.

13 Jul 2018

Scientists deliver nano-size packets of genetic code to treat brain tumors in mice

In a "proof of concept" study, scientists at Johns Hopkins Medicine say they have successfully delivered nano-size packets of genetic code called microRNAs to treat human brain tumors implanted in mice.

12 Jul 2018

Researchers elucidate role of mutations in deadly brain cancer

Researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have discovered how different mutations in a specific gene help drive glioblastoma, the most lethal form of brain cancer.

11 Jul 2018

Malignant News and Research

Tumor suppressor gene PTEN may be potential Achilles heel for breast cancer cells

How rival opioid makers sought to cash in on alarm over oxycontin’s dangers

Researchers discover key piece for slowing colorectal cancer subtype

Microscopic imaging helps better understand cancer bone metastasis

Janssen’s Darzalex receives positive CHMP opinion for treating multiple myeloma patients

New approach shows important role of microRNAs in papillomavirus life cycle

CNDA approves KEYTRUDA for treatment of advanced melanoma

MicroRNA panel could categorize indeterminate thyroid nodule samples into malignant and benign

Anti-cancer gene may switch side and promote cancer growth, shows study

New control system regulates morphology, orientation of cells constituting animal tissues

Turmeric derivative could be used in eye drops to treat early stages of glaucoma

Patients with colon cancers on the right side have worse survival rates than those with left-sided tumors

FDA approves first drug for treatment of adult AML patients with specific genetic mutation

Researchers develop new way to uncover hidden breast cancer tumors

New strategy may lead to more accurate breast cancer diagnoses

CT scans may raise brain tumor risk

Researchers reduce size of tumors in mice by artificially activating the brain's reward system

Managing multiple ipsilateral breast cancer with potential new surgical options

Scientists deliver nano-size packets of genetic code to treat brain tumors in mice

Researchers elucidate role of mutations in deadly brain cancer

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