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Scientific statement reframes cardiovascular care for older patients with cognitive impairment and frailty

Older adults with cardiovascular disease (CVD) often have coexisting cognitive impairment and frailty, conditions that can significantly affect treatment decisions, recovery, independence and quality of life and should be considered as part of an aging-informed approach to care, according to a new American College of Cardiology Scientific Statement published in JACC, the flagship journal of the ACC.

10 Aug 2026

New pathway explains how zombie cells trigger chronic inflammation

Researchers have uncovered a previously unknown mechanism that helps aging cells drive the chronic inflammation linked to many age-related diseases.

10 Aug 2026

Medical reassurance often stops patients from seeking treatment

Doctors may think they're saying "Don't panic." But many patients hear "Don't bother" instead.

10 Aug 2026

Simple biological age score flags higher cognitive decline risk in older adults

A study of 4,818 middle-aged and older Chinese adults found that higher light BioAge was associated with greater risks of cognitive impairment, episodic memory decline, and reduced mental intactness. The simple measure, based on age, creatinine, glucose, and CRP, added modest predictive information but requires further validation before clinical use.

10 Aug 2026

New USC center seeks answers to sex differences in aging

Women live longer than men in nearly every country in the world, yet they experience higher rates of disability, dementia and many other age-related conditions.

7 Aug 2026

New study reveals genetic drivers of inherited bone marrow failure syndrome

Inherited bone marrow failure syndrome, or IBMFS, describes a group of disorders in which inherited genetic abnormalities impair the bone marrow's ability to produce sufficient healthy blood cells.

6 Aug 2026

Nighttime light linked to conflicting signs of biological aging

Higher residential nighttime light exposure was associated with contrasting biological aging patterns in nearly 300,000 UK Biobank participants, depending on the aging algorithm used. PhenoAge and homeostatic dysregulation suggested a potentially adverse aging pattern, while KDM-BA showed the opposite association, underscoring uncertainty about how nighttime light relates to biological aging.

6 Aug 2026

PIWI proteins and piRNAs may unlock more effective stem cell therapies

Scientists are shedding new light on a little-known biological system that could help unlock the full potential of stem cell therapy, one of the most promising areas of modern medicine.

6 Aug 2026

New review links obesity with accelerated biological aging mechanisms

The global rise in obesity and population aging represents a major public health challenge, with growing evidence suggesting that excess body fat not only increases the risk of chronic disease but may also accelerate the biological aging process.

6 Aug 2026

Hyperfunction theory offers fresh insights into mechanisms driving human aging

A new research perspective was published in Volume 18 of Aging on July 24, 2026, titled "A brief history of the hyperfunction theory of aging and future directions."

6 Aug 2026

High-resolution scans reveal how depression affects hippocampal subfields

Researchers from the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have found that depression is associated with smaller volume in a specific part of the hippocampus, a brain region essential for learning and memory.

6 Aug 2026

Researchers map how blood cells cross into the brain during aging

The brain's immune system has long been thought to exist independently from the rest of the body, complete with its own specialized immune cells and a blood-brain barrier that limits what can travel into the brain.

6 Aug 2026

Healthy midlife habits linked to longer dementia-free years

Having normal blood pressure, no diabetes, and not smoking from age 48 to 68, are associated with nearly 13 additional years on average of dementia-free life, a new study shows.

6 Aug 2026

NIH funds Boston University center for Alzheimer's prevention studies

Maria Glymour, Andrew Stokes, and Deborah Carr will lead the Boston University-Quantitative Population Science and Healthy Cognitive Aging Research Program (BU-SHARP) to foster national research collaboration on preventing and ameliorating the consequences of Alzheimer's disease and related dementias in disproportionately affected populations.

5 Aug 2026

Cellular senescence drives progression of spinal disc degeneration and pain

A growing body of scientific insight is drawing attention to cellular senescence as a central force in the progression of intervertebral disc degeneration (IDD), a leading contributor to chronic low back pain worldwide.

5 Aug 2026

Specialized selenoproteins play critical role in regulating cellular health

A new review highlights the remarkable importance of selenoproteins, a specialized group of molecules that, despite their small size, play a decisive role in shaping cellular fate and maintaining biological balance.

5 Aug 2026

New metric detects early Alzheimer’s changes in brain's white matter

Alzheimer's disease has traditionally been studied as a condition that primarily affects the brain's gray matter, where neuronal cell bodies are located and some of the disease's most characteristic lesions accumulate.

5 Aug 2026

Type 2 diabetes linked to more severe menopause symptoms

The type of menopause symptoms, as well as their severity, can differ greatly among women. A number of earlier studies have suggested various reasons for those differences.

5 Aug 2026

The healthiest super-agers may have one thing in common: stable cognition

A 10-year study of 1,003 older adults linked cognitive super-aging to fewer emergency visits, unplanned hospital admissions, delirium episodes, dementia diagnoses, and residential aged care placements. Maintaining cognitive performance over time showed the strongest overall association with favorable health outcomes and was linked to a 46% lower mortality risk.

5 Aug 2026

New study advances understanding of dementia after age 90

It may seem natural to assume that people experience cognitive decline after age 90, but until recently, researchers had limited evidence about how advanced age affects the brain.

4 Aug 2026