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Vaccination reduces risk of severe COVID-19 in solid organ transplant recipients

Findings from a two-year study of nearly 2,400 solid organ transplant recipients, conducted by the Johns Hopkins Transplant Research Center (TRC) in collaboration with the New York University Center for Surgical and Applied Transplant Research, indicate spikes of post-vaccination SARS-CoV-2 viral infections (commonly known as COVID-19 breakthrough cases) remain common, yet hospitalization rates have dramatically dropped following the first wave of the virus' omicron subvariant.

18 Aug 2023

Severe COVID-19 may cause long-term changes to innate immune system

Severe COVID-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, according to a small study funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

18 Aug 2023

Researchers develop platform allowing mass-scale production of SARS-CoV-2 mRNA lipid nanoparticle vaccines

Researchers presented a scalable lipid nanoparticle production (SCALAR) platform to develop SARS-CoV-2 mRNA lipid nanoparticle vaccines.

15 Aug 2023

Pairing top-down and bottom-up approaches to gain insights into the origin of life

Despite decades of progress, the origin of life remains one of the great unsolved problems in science.

14 Aug 2023

Scientists capture first images of ribosome-modifying enzymes in action

Bacteria draw from an arsenal of weapons to combat the drugs intended to kill them. Among the most prevalent of these weapons are ribosome-modifying enzymes.

14 Aug 2023

Unveiling α1-AR secrets: breakthrough structures and targeted drug design

Researchers explored the structural basis of agonist specificity of α1A-adrenergic receptors (α1-ARs).

14 Aug 2023

Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

The researchers demonstrated that glucokinase activation was effective in lowering blood glucose in mice with high-fat diet-induced obesity, while it potentially raised the risk of increasing hepatic lipid accumulation that triggered the PERK-UPR pathway.

11 Aug 2023

COVID-19 mRNA vaccine or booster during pregnancy benefits mother and baby, study finds

Receiving a COVID-19 mRNA vaccine or booster during pregnancy can benefit pregnant people and their newborn infants, according to findings recently published in Vaccine.

11 Aug 2023

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Researchers used a multidisciplinary approach to investigate a nonstructural protein essential in SARS-CoV-2 replication.

10 Aug 2023

Ebola virus forms "viral factories" to replicate inside host cells

New research in the journal Nature Communications gives scientists an important window into how Ebola virus replicates inside host cells.

9 Aug 2023

Mitochondrial protein structure activates cell's integrated stress response

Often referred to as the "powerhouses of the cell," mitochondria are well known for their role as energy suppliers, but these organelles are also critical for maintaining our overall health.

8 Aug 2023

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

B cells or B lymphocytes are an important part of the body's immune system. When healthy B cells are infected with the Epstein-Barr virus (EBV), they undergo growth transformation, a process that immortalizes B cells, leading to their uncontrolled proliferation.

7 Aug 2023

New technique enables high-resolution analysis of DNA

Function and form are deeply intertwined in biology. Knowing how organisms grow, adapt and reproduce requires understanding their physical structures. Hence the transformative power of the microscope across the past four centuries of science.

4 Aug 2023

Cryo-EM structures and functions of potent bispecific antibodies against multiple Omicron sublineages

Researchers characterizes the structures and functions of potent bispecific antibodies against multiple Omicron subvariants using Cryo-EM.

3 Aug 2023

Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load

In a recent study, researchers working at Ohio State University in the United States of America (USA) developed an intranasal subunit vaccine.

2 Aug 2023

New study spotlights effective strategy against COVID-19 variants: the E7 monoclonal antibody

Researchers developed potent monoclonal antibodies from a severe acute respiratory syndrome coronavirus (SARS-CoV) survivor.

1 Aug 2023

New way to create unnatural amino acids identified

Every protein in your body is made up of the same 20 building blocks called amino acids. But just because nature is stuck with a limited toolkit doesn't mean humans can't expand it.

1 Aug 2023

Researchers investigate the efficacy of a novel intra-tumoral drug delivery carrier in treating oral squamous cell carcinoma

Researchers investigated the efficacy of a novel intra-tumoral drug delivery carrier in treating oral squamous cell carcinoma.

31 Jul 2023

Cryo-EM study elucidates 3D structure and molecular mechanism of platelet drug transporter

A research team led by Prof. CHEN Yuxing and Prof. ZHOU Cong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) recently utilized single-particle cryogenic electron microscopy (cryo-EM) to decipher the 3D structure and molecular mechanism of the platelet drug transporter ABCC4.

28 Jul 2023

New nano-immune magnetic bead developed for efficient SARS-CoV-2 virus detection

A more efficient way to test SARS-CoV-2 Virus was developed recently by a research team led by Professor WANG Junfeng from Hefei Institutes of Physical Science (HFIPS), Chinese Academy of Science (CAS).

28 Jul 2023

Electron News and Research

Vaccination reduces risk of severe COVID-19 in solid organ transplant recipients

Severe COVID-19 may cause long-term changes to innate immune system

Researchers develop platform allowing mass-scale production of SARS-CoV-2 mRNA lipid nanoparticle vaccines

Pairing top-down and bottom-up approaches to gain insights into the origin of life

Scientists capture first images of ribosome-modifying enzymes in action

Unveiling α1-AR secrets: breakthrough structures and targeted drug design

Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

COVID-19 mRNA vaccine or booster during pregnancy benefits mother and baby, study finds

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Ebola virus forms "viral factories" to replicate inside host cells

Mitochondrial protein structure activates cell's integrated stress response

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

New technique enables high-resolution analysis of DNA

Cryo-EM structures and functions of potent bispecific antibodies against multiple Omicron sublineages

Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load

New study spotlights effective strategy against COVID-19 variants: the E7 monoclonal antibody

New way to create unnatural amino acids identified

Researchers investigate the efficacy of a novel intra-tumoral drug delivery carrier in treating oral squamous cell carcinoma

Cryo-EM study elucidates 3D structure and molecular mechanism of platelet drug transporter

New nano-immune magnetic bead developed for efficient SARS-CoV-2 virus detection

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