Gene Sequencing News and Research

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New method may be effective at quantifying DNA adenine methylation in complex organisms

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.

3 Feb 2022

Protocol for a systematic review to evaluate the role of viral cultures for assessing airborne transmission of SARS-CoV-2

Researchers presented the protocol for a systematic review assessing viral cultures for airborne transmission of SARS-CoV-2.

3 Feb 2022

N gene target failure method effectively detects SARS-CoV-2 Omicron in clinical samples

In a new study, researchers demonstrated that a commercial real-time polymerase chain reaction (RT-PCR) assay rapidly detects the SARS-CoV-2 Omicron variant.

2 Feb 2022

Rapid DNA sequencing technique used to diagnose rare genetic disease in short time

A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours — a feat that's nearly unheard of in standard clinical care.

19 Jan 2022

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours - a feat that's nearly unheard of in standard clinical care.

13 Jan 2022

Providing recombinant antibody services and more within Europe

In this interview, News-Medical talks to Dr. Zhang Linlin, Technical Specialist at Sino Biological Europe, about their recombinant antibody services and more that they can provide within Europe. Image credit: Corona Borealis Studio/Shutterstock.com

From Sino Biological Inc. 11 Jan 2022

Genomic variant may help predict which patients will experience chemotherapy-induced cardiotoxicity

A team of investigators have discovered a genomic variant that may help clinicians predict which patients will experience cardiotoxicity from a widely used chemotherapy drug, according to a Northwestern Medicine study published in Circulation.

3 Jan 2022

Mutations in a crucial gene responsible for chemotherapy failure in some blood cancer patients

Mutations in a crucial gene are the key reason that chemotherapy fails in some patients with blood cancer, a study by Nanyang Technological University, Singapore (NTU Singapore) and Singapore General Hospital (SGH) has found.

6 Dec 2021

Study reveals mechanism by which vitamin D reduces inflammation caused by immune cells

Scientists recently gained insights into how vitamin D functions to reduce inflammation caused by immune cells that might be relevant to the responses during severe COVID-19. In a study jointly published by Purdue University and the National Institutes of Health, scientists do just that.

18 Nov 2021

Routine surveillance helps detect asymptomatic SARS-CoV-2 vaccine breakthrough infections

In a study published in Annals of Internal Medicine, researchers from Italy systematically monitored 2,397 HCWs who were fully vaccinated with BNT162 at the ASST Settelaghi hospitals in Lombardy, Italy during February 2021. HCWs who worked in 8 wards deemed at “high risk” for infection from attending patients had to undergo mandatory nasopharyngeal swab testing with SARS-CoV-2 polymerase chain reaction every two weeks. HCWs working in 8 “moderate-risk” wards were tested every four weeks.

28 Oct 2021

Regular testing of SARS-CoV-2 positive vaccinated HCWs may reduce need for long quarantines

A new study published in the journal Annals of Internal Medicine conducted systematic surveillance involving 2,397 HCWs who were fully vaccinated with the Pfizer-BioNTech BNT162 vaccine at the ASST Settelaghi hospitals, Italy, in February 2021.

19 Oct 2021

Instability in gut microbiota associated with COVID-19-related complications and mortality, study finds

Researchers from Germany recently analyzed saliva and fecal samples from SARS-CoV-2 infected and post-COVID-19 patients and controls while considering multiple influencing factors during hospitalization. This study is available on the bioRxiv* preprint server.

13 Oct 2021

Adapting biological research and development to COVID-19

In this interview, News-Medical talks to Dr Yuning Chen, about the work he does with Sino Biological and how they have adapted their research & development to the COVID-19 pandemic.

From Sino Biological Inc. 8 Oct 2021

Researchers create an integrated pipeline for performing genetic screening studies

Today's genetic engineers have a plethora of resources at their disposal: an ever-increasing number of massive datasets available online, highly precise gene editing tools like CRISPR, and cheap gene sequencing methods. But the proliferation of new technologies has not come with a clear roadmap to help researchers figure out which genes to target, which tools to use, and how to interpret their results. So, a team of scientists and engineers at Harvard's Wyss Institute for Biologically Inspired Engineering, Harvard Medical School (HMS), and the MIT Media Lab decided to make one.

28 Sep 2021

Gut microbiome patterns provide clues to brain damage in extremely premature infants

Extremely premature infants are at a high risk for brain damage. Researchers at the University of Vienna and the Medical University of Vienna have now found possible targets for the early treatment of such damage outside the brain: Bacteria in the gut of premature infants may play a key role.

4 Sep 2021

New AHA statement provides guidance about cardiovascular genetic testing in children

Cardiovascular genetic testing in children presents unique challenges, requiring pre- and post-test counseling with an individualized approach for families.

20 Aug 2021

Scientists discover genetic basis and molecular mechanisms of new neurodevelopmental syndrome

Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that variants in the SPTBN1 gene can alter neuronal architecture, dramatically affecting their function and leading to a rare, newly defined neurodevelopmental syndrome in children.

1 Jul 2021

Researchers explore potential exposure to microbial agents in-utero

The human fetal immune system begins to develop early during gestation, however, factors responsible for fetal immune-priming remain elusive.

16 Jun 2021

Researchers develop new technology to reduce high error rates in gene sequencing

Next-generation gene sequencing (NGS) technologies --in which millions of DNA molecules are simultaneously but individually analyzed-- theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood stream.

4 May 2021

New portable viral screening test can diagnose COVID-19 in minutes and track variants

Clinicians using a new viral screening test can not only diagnose COVID-19 in a matter of minutes with a portable, pocket-sized machine, but can also simultaneously test for other viruses--like influenza--that might be mistaken for the coronavirus.

31 Mar 2021