Heart Defect News and Research

RSS

New research shows that spontaneous mutations contribute to congenital heart disease

Every year, thousands of babies are born with severely malformed hearts, disorders known collectively as congenital heart disease. Many of these defects can be repaired though surgery, but researchers don't understand what causes them or how to prevent them. New research shows that about 10 percent of these defects are caused by genetic mutations that are absent in the parents of affected children.

13 May 2013

Nutritional supplement may improve survival rates of babies born with heart defects

A common nutritional supplement may be part of the magic in improving the survival rates of babies born with heart defects, researchers report. Carnitine, a compound that helps transport fat inside the cell powerhouse where it can be used for energy production, is currently used for purposes ranging from weight loss to chest pain.

10 May 2013

Researchers use contrast-computed tomography for anatomical reconstruction of human heart

On April 18th JoVE (Journal of Visualized Experiments) will publish a new video article by Dr. Paul A Iaizzo demonstrating the anatomical reconstruction of an active human heart. The research uses contrast-computed tomography (CT) to allow in-depth 3-D computer modeling of hearts that can be used for prolonged archiving.

22 Apr 2013

CWRU, UH Neurological Institute to present 2013 Neurocritical Care & Stroke Conference

University Hospitals (UH) Neurological Institute, in partnership with Case Western Reserve University School of Medicine, will present the 10th Annual Cleveland Neurocritical Care & Stroke Conference: With a Little Help From My Friends on March 8, 2013 at Case Western Reserve University's Iris S. and Bert L. Wolstein Research Building.

18 Dec 2012

Whole genome sequencing could become prenatal standard of care

Whole genome sequencing of the DNA code of prenatal samples accurately and quickly identifies the location of chromosomal abnormalities, and could become a prenatal standard of care, researchers propose.

9 Nov 2012

Cardiac arrhythmias: an interview with Dr Andrew Grace

Cardiac arrhythmias are disturbances of the heartbeat. The heart can either go too slowly, which might make people collapse or exhausted; or too quickly.

8 Nov 2012

Studies provide first clues of balanced de novo chromosomal rearrangements

Whole genome sequencing of the DNA code of three prenatal samples provided a detailed map of the locations of their chromosomal abnormalities in 14 days, scientists reported today at the American Society of Human Genetics (ASHG) 2012 meeting in San Francisco.

8 Nov 2012

Four transcription factor genes control processes related to heart and head muscle formation

A group of researchers in Israel, the United States and other nations have made important advances in the rapidly-expanding field of "regenerative medicine," outlining for the first time connections in genetic regulation that normally prevent birth defects in heart and facial muscles.

30 Oct 2012

Major academic medical centers, teaching hospitals to form Chicago Adult Congenital Heart Network

Seven major academic medical centers and teaching hospitals in the Chicago area have joined together to form the Chicago Adult Congenital Heart Network (CATCH), which is the first patient-centered, inter-institutional network in Chicago established to ensure all adults with congenital heart disease in the area receive appropriate follow-up care.

16 Oct 2012

Two tiny RNA molecules play a key role in pathological heart growth and failure

Cardiac stress, for example a heart attack or high blood pressure, frequently leads to pathological heart growth and subsequently to heart failure. Two tiny RNA molecules play a key role in this detrimental development in mice, as researchers at the Hannover Medical School and the Göttingen Max Planck Institute for Biophysical Chemistry have now discovered.

26 Sep 2012

Medicare policies continue to claim campaign trail attention

The presidential and vice presidential candidates compare and contrast their plans, and some fact checkers set to work on sorting out what they are saying.

15 Sep 2012

Convention news: Dems embrace health law

In speeches from the podium and in the buzz from the convention floor, it was apparent on the first day of the Democratic National Convention that delegates and speakers aimed to reclaim the health law as an important accomplishment of the Obama administration.

6 Sep 2012

Home is where the heart is for congenital defect children

The American Heart Association recommends that children with a congenital heart defect deemed as being at high risk for developmental disorders are treated under a “medical home” model of care.

3 Aug 2012

Kids with congenital heart defect should receive early evaluation for developmental disorders

Children born with a congenital heart defect should receive early evaluation, prompt treatment and ongoing follow-up for related developmental disorders affecting brain function, according to a new American Heart Association scientific statement published in Circulation.

31 Jul 2012

Heart defects at birth linked to workplace exposure to solvents

Workplace exposure to organic solvents is linked to several types of heart defects at birth, indicates research published online in Occupational and Environmental Medicine.

18 Jul 2012

BCVI introduces comprehensive program for patients with BAV

Bicuspid aortic valve (BAV) disease is the most common congenital heart defect, occurring in approximately one to two percent of the population. The condition is present when the aortic valve, the valve that connects the heart to the main artery that distributes blood to the body, contains two leaflets instead of three, which open and close to regulate blood flow. As a result, the valve does not function properly, which can cause strain on the heart over time and may lead to serious health complications.

4 Jul 2012

TCFC completes two in-utero fetal cardiac interventions to treat HLHS

The team at Texas Children's Fetal Center, a national leader for treating fetal anomalies, has successfully completed two in-utero fetal cardiac interventions to treat hypoplastic left heart syndrome (HLHS), a congenital heart defect that is one of the most complex heart defects to treat.

5 May 2012

Enrollment complete for In-tunnel SeptRx European PFO Trial in Europe

SeptRx, an emerging medical device company that has developed the SeptRx Intrapocket PFO Occluder (IPO), reported today that it has completed enrollment for its "InterSEPT" (In-tunnel SeptRx European PFO Trial) clinical trial in Europe, and has entered into a partnership with CoRRect Medical GmbH for commercial distribution in Germany and Switzerland of the SeptRx IPO.

23 Apr 2012

March of Dimes selects UTMB scientist to receive Basil O'Connor Starter Scholar Award

The March of Dimes Foundation has chosen University of Texas Medical Branch at Galveston assistant professor Muge Kuyumcu-Martinez to receive a two-year, $150,000 Basil O'Connor Starter Scholar Award. The grant will support her research on congenital heart defects, the most common type of major birth defect.

21 Apr 2012

Innate patient factors, overall morbidity affect neurodevelopment in infants with single-ventricle disease

In the largest multicenter clinical trial of children undergoing early-stage surgery for single-ventricle heart defects, differences in intraoperative management did not significantly affect neurodevelopmental outcomes at 14 months of age. Instead, the strongest influences were innate patient characteristics and general medical morbidity during the child's first year of life.

6 Apr 2012