Hepatitis B Virus News and Research

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New AI blood testing technology detects more than 80% of liver cancers

A novel artificial intelligence blood testing technology developed and used by Johns Hopkins Kimmel Cancer Center researchers to successfully detect lung cancer in a 2021 study has now detected more than 80% of liver cancers in a new study of 724 people.

20 Nov 2022

Bispecific antibodies neutralize Sarbecoviruses with increased breadth and potency

In a recent study posted to the bioRxiv* preprint server, researchers developed bispecific antibodies (bsAbs), neutralizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.

17 Nov 2022

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

A new study aimed to analyze the molecular interactions between the hCypA protein and the SARS-CoV-2 variants to determine the impact of variants on the blocking and binding potential of the hCypA–S protein complex with the ACE2 receptor.

2 Nov 2022

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

A team led by scientists at Scripps Research and the University of Amsterdam has achieved an important goal in virology: mapping, at high resolution, critical proteins that stud the surface of the Hepatitis C virus (HCV) and enable it to enter host cells.

20 Oct 2022

Three-dose course of the hepatitis B vaccine fully protects adults living with HIV

A three-dose course of the hepatitis B vaccine HEPLISAV-B fully protected adults living with HIV who had never been vaccinated against or infected with the hepatitis B virus (HBV), according to study findings presented today at the IDWeek conference in Washington, D.C.

20 Oct 2022

Inhalation therapeutics against COVID-19

A recent study published in the Pulmonary Pharmacology & Therapeutics journal described different inhalation therapeutic agents for treating respiratory viral infections like coronavirus disease 2019 (COVID-19).

17 Oct 2022

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

A new paper reviews current knowledge of RdRp inhibitors that could be developed further to provide broadly effective antivirals against SARS-CoV-2 in particular and CoVs in general.

10 Oct 2022

Chronic liver disease in COVID-19 patients

A recent study summarizes the clinical outcomes of COVID-19 patients with chronic liver disease.

10 Oct 2022

The involvement of minor intron-containing gene-encoded proteins in viral infections

Researchers explored the role of the minor intron-containing gene (MIG)-encoded proteins (MIG-Ps) depending on minor spliceosome-MiG excision to be expressed in infections by pathogenic viruses.

6 Oct 2022

Global burden of liver cancer could rise by more than 55% by 2040, analysis reveals

A new analysis reveals that primary liver cancer was among the top three causes of cancer death in 46 countries in 2020 and the number of people diagnosed with or dying from primary liver cancer per year could rise by more than 55% by 2040.

5 Oct 2022

BU investigator wins highly competitive awards to study the role of proteases in regulation of cellular defenses

Mohsan Saeed, PhD, assistant professor of biochemistry at Boston University School of Medicine (BUSM), has received a five-year, $2 million R35 grant from the National Institute of General Medical Sciences, as well as a five-year, $2.5 million R01 grant from the National Institute of Allergy and Infectious Diseases.

20 Sep 2022

Altered T-cell response in hemodialysis patients following third COVID-19 vaccine dose

Scientists define the immune responses against COVID-19 in HD patients who received three mRNA COVID-19 vaccine doses.

13 Sep 2022

NIH animal study combines Paxlovid with Lagevrio against SARS-CoV-2 Delta

In a recent study posted to the bioRxiv* preprint server, researchers at the U.S National Institutes of Health demonstrated the efficacy of molnupiravir and nirmatrelvir, two oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals in the rhesus macaque model, the closest proxy to humans.

7 Sep 2022

The currently available evidence on viral-induced parkinsonism

A new review attempts to summarize all known about the relationship between viral illness and parkinsonian disorders to facilitate further research.

31 Aug 2022

New immunological treatment against hepatitis B and D viruses shows promising results in animal models

A new immunological treatment against hepatitis B and D viruses, both of which can cause liver cancer, shows promising results in animal models.

26 Aug 2022

Immune therapy may be an alternate therapeutic approach for treating chronic hepatitis B

Hepatitis B virus (HBV) infection is global in nature and induces several incredible liver diseases, such as chronic hepatitis B (CHB), cirrhosis of the liver (LC) and hepatocellular carcinoma (HCC). A total of 882,000 patients died of HBV-related liver diseases in 2019.

25 Aug 2022

The safety, tolerability, and pharmacokinetics of a muco-trapping monoclonal antibody delivered by inhalation

Researchers conducted a phase I clinical trial of IN-006, an inhaled monoclonal antibody treatment for COVID-19.

24 Aug 2022

Direct acting antiviral medications for hepatitis C may improve PTSD symptoms

More than six percent of Americans will develop posttraumatic stress disorder (PTSD) in their lifetime. This potentially chronic condition disrupts lives, and can lead to or exacerbate existing health issues such as depression, anxiety, eating disorders, and suicidal thoughts.

22 Aug 2022

Study provides insights into understanding the biology of circulating Hepatitis E variants

Over three million people are infected with the hepatitis E virus every year. So far, no effective treatment is available. An international team has investigated which factors are important for the virus in the course of its replication cycle and how it manages to maintain the infection.

17 Aug 2022

Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

Researchers investigated the susceptibility of naturally-occurring severe acute respiratory syndrome coronavirus 2 main protease variants to protease inhibitor drugs, including nirmatrelvir and ensitrelvir.

11 Aug 2022