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A deeper look at COVID-19 transmission and fetal health

A new Cleveland Clinic-led study published in The EMBO Journal shows that mild and asymptomatic SARS-CoV-2 infections can trigger immune responses in a pregnant individual that may cause serious inflammatory responses in the developing fetus.

17 Oct 2024

New test developed to simplify the diagnosis of allergies

Researchers at the University of Bern and Bern University Hospital have developed a test to simplify the diagnosis of allergies.

15 Oct 2024

Exploring the role of gut microbes in the aging process

Aging is a universal and complex process affecting all organisms, characterized by several genetic hallmarks such as telomere attrition, genomic instability, and epigenetic changes.

9 Oct 2024

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Researchers used stem-cell derived organoids from Crohn's disease patients to identify two molecular subtypes, paving the way for personalized treatments targeting specific disease characteristics.

2 Oct 2024

Long-lived plasma cells fail to establish after COVID mRNA vaccination, limiting long-term antibody response

Researchers found that SARS-CoV-2-specific plasma cells were largely excluded from the long-lived plasma cell compartment in the bone marrow after mRNA vaccination, explaining the short-lived antibody response.

2 Oct 2024

Cleveland Clinic identifies bacterium that weakens gut immune defense

Cleveland Clinic researchers have discovered a new bacterium that weakens the immune system in the gut, potentially contributing to certain inflammatory and infectious gut diseases.

26 Sep 2024

Johnson & Johnson seeks first approval of nipocalimab to treat broadest population living with antibody positive generalized myasthenia gravis

The BLA submission for nipocalimab marks a significant advancement in treating generalized myasthenia gravis, showing improved MG-ADL scores in clinical trials.

From Johnson & Johnson 24 Sep 2024

Key triggers for food allergies in children after organ transplants

Study reviews transplant-acquired food allergies, focusing on pediatric patients, particularly liver transplant recipients. It explores immune system dysfunction, immunosuppressive agents, and gut microbiota changes as contributors to the rise of food allergies after organ transplants.

23 Sep 2024

How plant-based, Mediterranean, and Western diets affect gut microbiota and disease

Researchers examine how different dietary components affect the gut microbiome and development of non-communicable diseases.

20 Sep 2024

Immune proteins in tooth enamel provide clues about ancient human health

A new way of looking at tooth enamel could give scientists a path to deeper understanding of the health of human populations, from the ancient to the modern.

19 Sep 2024

Long COVID patients maintain robust immune memory two years after infection

Researchers discovered that SARS-CoV-2-specific T and B cells in long COVID patients are maintained for two years, similar to fully recovered individuals, offering insights into long-term immunity.

17 Sep 2024

Mucosal COVID-19 boosters outperform mRNA shots in preventing upper airway infections

Aerosolized mucosal vaccines show promise in controlling SARS-CoV-2, offering greater protection and immune response than intramuscular bivalent mRNA boosters.

5 Sep 2024

New insights into stiff-person syndrome, advancing diagnosis and treatment

Research explores the complexities of diagnosing and treating stiff-person syndrome, emphasizing the uncertain role of GAD antibodies and the promise of novel therapies.

5 Sep 2024

Early viral activity plays critical role in long COVID, study suggests

Findings on early viral and immune markers provide insights into the pathogenesis of post-acute sequelae of SARS-CoV-2, informing future research and therapies.

2 Sep 2024

Intranasal vaccine shows broad SARS-CoV-2 variant protection

Study demonstrates that a single-dose intranasal live-attenuated vaccine, CDO-7N-1, provides broad protection against SARS-CoV-2 and its variants by inducing potent immune responses, including neutralizing antibodies and T-cell activity, in animal models.

1 Sep 2024

CDC study reveals critical gaps in hantavirus detection across the U.S. due to inconsistent testing standards

Researchers map the prevalence and genotype distribution of hantavirus in the U.S., highlighting significant regional differences and the need for standardized testing

25 Aug 2024

Octavalent intranasal flu vaccine proves effective in neutralizing both existing and emerging strains

A new octavalent intranasal vaccine shows promising results in providing broad immunity against both seasonal and pre-pandemic influenza strains by eliciting strong mucosal and systemic immune responses in ferrets.

25 Aug 2024

Engineered human cardiac tissue reveals how lupus autoantibodies damage the heart

Study demonstrates that autoantibodies in systemic lupus erythematosus (SLE) patients contribute to myocardial injury by binding to and impairing stressed cardiac cells, offering insights into potential therapeutic targets.

25 Aug 2024

How the MIND diet may protect against dementia

Researchers utilize transcriptomic data to examine the protective effects of the MIND diet in reducing the risk of dementia and slowing cognitive decline.

20 Aug 2024

New targets for improved cancer immunotherapy

In the past two decades, immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, showing promising results against various solid tumors. This study reviews recent developments in ICIs, focusing on new targets like T cell immunoreceptors with Ig and ITIM domains (TIGIT), T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), and lymphocyte activation gene-3 (LAG-3). These targets aim to overcome resistance mechanisms limiting the effectiveness of current therapies, such as anti-PD-1 and anti-CTLA-4. By identifying and developing these new ICIs, researchers hope to improve treatment outcomes and provide new therapeutic options for cancer patients.

14 Aug 2024

Immunoglobulin News and Research

A deeper look at COVID-19 transmission and fetal health

New test developed to simplify the diagnosis of allergies

Exploring the role of gut microbes in the aging process

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Long-lived plasma cells fail to establish after COVID mRNA vaccination, limiting long-term antibody response

Cleveland Clinic identifies bacterium that weakens gut immune defense

Johnson & Johnson seeks first approval of nipocalimab to treat broadest population living with antibody positive generalized myasthenia gravis

Key triggers for food allergies in children after organ transplants

How plant-based, Mediterranean, and Western diets affect gut microbiota and disease

Immune proteins in tooth enamel provide clues about ancient human health

Long COVID patients maintain robust immune memory two years after infection

Mucosal COVID-19 boosters outperform mRNA shots in preventing upper airway infections

New insights into stiff-person syndrome, advancing diagnosis and treatment

Early viral activity plays critical role in long COVID, study suggests

Intranasal vaccine shows broad SARS-CoV-2 variant protection

CDC study reveals critical gaps in hantavirus detection across the U.S. due to inconsistent testing standards

Octavalent intranasal flu vaccine proves effective in neutralizing both existing and emerging strains

Engineered human cardiac tissue reveals how lupus autoantibodies damage the heart

How the MIND diet may protect against dementia

New targets for improved cancer immunotherapy

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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