Malignant News and Research

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New nanomaterial kills cancer cells via oxidative stress

Scientists at Oregon State University have developed a new nanomaterial that triggers a pair of chemical reactions inside cancer cells, killing the cells via oxidative stress while leaving healthy tissues alone.

28 Jan 2026

Physical behavior reveals aggressive cancer cells in a simple new approach

New study shows that aggressive cancer cells can be identified in a simple, new way; by how they physically behave, not just by their genes.

26 Jan 2026

Metabolic reprogramming drives prostate cancer progression and treatment resistance

Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer (CRPC).

24 Jan 2026

Cigarette compound exposure drives sorafenib resistance in hepatocellular carcinoma

A research team led by Professor Yuan Li at Nanjing Medical University published a research paper entitled "A Cigarette Compound-Induced Tumor Microenvironment Promotes Sorafenib Resistance in Hepatocellular Carcinoma via the 14-3-3η-Modified Tumor-Associated Proteome" in the Chinese Medical Journal.

23 Jan 2026

FDA warns consumers about fake cancer cures sold online

Beware of products claiming to cure cancer on websites or social media platforms, such as Facebook and Instagram. According to Nicole Kornspan, M.P.H., a consumer safety officer at the U.S. Food and Drug Administration (FDA), they're rampant these days.

22 Jan 2026

Customizable protein platforms offer new hope for cancer treatment

Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at the University of Massachusetts Amherst, could have applications beyond cancer to a wide range of immunological diseases, members of the interdisciplinary research team say.

20 Jan 2026

Bio-detection dogs can sniff out hemangiosarcoma

Cancer is a leading cause of death in both humans and pets; studies suggest that between one-third and one-half of all dogs will develop cancer during their lifetime.

20 Jan 2026

Single-cell technique maps pre-malignant gene mutations in solid tissues

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the New York Genome Center.

16 Jan 2026

Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial

A recent publication in Nature Medicine describes a novel immunotherapy targeting pancreatic cancer that has shown promising results in a first in-human phase 1/2 trial.

13 Jan 2026

Targeting IDO1 for cancer: Novel degraders show promise in preclinical studies

Cancer cells employ a variety of strategies to evade the immune system, and modern immunotherapies aim precisely at these escape mechanisms.

9 Jan 2026

Immune cell atlas may improve survival predictions, guide treatment decisions in multiple myeloma

aps the immune cell landscape of bone marrow in patients with multiple myeloma, a rare cancer that develops in the plasma cells of the bone marrow and has no cure.

9 Jan 2026

Unveiling IDH-mutant glioma's roots: A new path for early diagnosis

IDH-mutant glioma, caused by abnormalities in a specific gene (IDH), is the most common malignant brain tumor among young adults under the age of 50.

8 Jan 2026

Novel approach uncovers possible drugs based on specific cellular targets for treating glioblastoma

Researchers have developed a new computational approach that uncovers possible drugs for specific cellular targets for treating glioblastoma, a lethal brain tumor.

7 Jan 2026

AI-powered optical imaging helps surgeons identify thyroid cancer in real time

Thyroid cancer is the most common endocrine cancer, affecting more people each year as detection rates continue to rise.

6 Jan 2026

Using contrast-enhanced ultrasound to distinguish hepatic PEComa from HCC without high-risk factors

Announcing a new article publication for BIO Integration journal. Hepatic perivascular epithelioid cell tumor (PEComa) is a rare tumor with malignant potential that is frequently misdiagnosed as hepatocellular carcinoma (HCC), despite requiring distinct treatment approaches.

6 Jan 2026

Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer

A new study published today in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in patients with an aggressive subtype of triple-negative breast cancer.

26 Dec 2025

Combination therapy shows promise to treat a rare, catastrophic pediatric brain cancer

St. Jude Children's Research Hospital scientists identified a promising combination approach to treat a rare, but catastrophic pediatric brain cancer called atypical teratoid rhabdoid tumor (ATRT).

16 Dec 2025

Bifunctional biomaterials for postoperative management of osteosarcoma

Osteosarcoma is the most prevalent primary malignant bone tumor in children and adolescents. The current standard treatment involves a combination of chemotherapy and radical surgical resection.

16 Dec 2025

Indoor tanning loads normal skin with mutations linked to melanoma

Indoor tanning is associated with markedly higher mutation burdens and cancer-driving genetic changes in melanocytes taken from normal-appearing skin, including areas usually protected from sunlight. These molecular alterations provide a biological explanation for the higher odds of melanoma and multiple primary tumors seen in heavy tanning bed users.

15 Dec 2025

New insights into alcohol-related DNA damage and cancer risk

Alcohol consumption leads to the formation of a toxic compound called acetaldehyde, which damages DNA.