Neglected Tropical Disease News and Research

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Calcium receptor – potential drug target for sleeping sickness

While its common name may make it sound almost whimsical, sleeping sickness, or African trypanosomiasis, is in reality a potentially fatal parasitic infection that has ravaged populations in sub-Saharan Africa for decades, and it continues to infect thousands of people every year.

19 Jan 2013

MSF, DNDi analysis shows increased investment in NTDs but low number of new therapy approvals

"Over the past decade, neglected diseases have attracted increased attention and larger investments in research," but "a new analysis by Medecins Sans Frontieres (MSF) and the Drugs for Neglected Diseases Initiative (DNDi) finds that the rate of approvals for new compounds over the past decade is roughly the same as it was during the previous two-and-a-half decades, when the diseases received little attention," Nature Medicine reports.

10 Jan 2013

Reviewing G-FINDER report findings

Nick Chapman, a policy analyst at Policy Cures, writes in a guest post on the Global Health Technologies Coalition's "Breakthroughs" blog about "the results of the latest G-FINDER survey on global funding of [research and development (R&D)] for neglected diseases."

21 Dec 2012

Blogs respond to attacks against polio workers in Pakistan

The following blog posts were published in response to a series of attacks against polio workers in Pakistan this week, which have left eight dead since Monday.

21 Dec 2012

Blogs discuss conference on neglected diseases

Several blogs recently reported on issues discussed last week during a conference sponsored by Medecins Sans Frontieres (MSF), the Drugs for Neglected Diseases initiative (DNDi), and the Mount Sinai School of Medicine in New York, titled "Lives in the Balance: Delivering Medical Innovations for Neglected Patients and Populations."

18 Dec 2012

Conference addresses issues of innovation for neglected diseases

Medecins Sans Frontieres, the Drugs for Neglected Diseases initiative, and the Mount Sinai School of Medicine this week are hosting a conference in New York, titled "Lives in the Balance: Delivering Medical Innovations for Neglected Patients and Populations," the Philadelphia Inquirer reports.

15 Dec 2012

Fatal imbalance between global disease burden and drug development

Despite important progress in research and development (R&D) for global health over the past decade, only a small fraction of new medicines developed between 2000 and 2011 were for the treatment of neglected diseases, highlighting the 'fatal imbalance' between global disease burden and drug development for some of the world most devastating illnesses, said Doctors Without Borders/M-decins Sans Fronti-res (MSF) and the Drugs for Neglected Diseases initiative (DNDi), in an analysis to be presented today at an international conference aimed at spurring medical innovations for these diseases.

13 Dec 2012

TU Darmstadt’s biosensor can diagnose African sleeping sickness before it breaks out

African sleeping sickness is an infectious disease that is widespread south of the Sahara Desert. Although the around sixty million people residing in tropical Africa run the risk of becoming infected with the disease every day, only around four million of them are monitored for the disease by disease-control authorities.

13 Dec 2012

Drugs for Neglected Diseases receives UNITAID grant for paediatric HIV programme

The Drugs for Neglected Diseases initiative welcomes the announcement by UNITAID to grant up to USD 17.3 million to the organization for its paediatric HIV programme.

12 Dec 2012

Fexinidazole enters Phase II/III clinical study to treat sleeping sickness

A new oral-only treatment for sleeping sickness has entered Phase II/III clinical study in patients with late-stage sleeping sickness in the Democratic Republic of the Congo (DRC) and soon in Central African Republic (CAR).

6 Dec 2012

Examining the definition of neglected diseases

"There's no generally accepted definition" for what characterizes a neglected disease, Kaitlin Christenson, coalition director for the Global Health Technologies Coalition (GHTC), writes in the Results for Development Institute's "Center for Global Health R&D Policy Assessment" blog.

6 Dec 2012

Report examines international funding for neglected diseases

"International financial support aimed at counteracting the world's 'neglected diseases' increased by nearly a half-billion dollars over the past five years, according to new research released Monday, but changing funding dynamics could already be having a negative impact on the development of cures for diseases that affect a substantial proportion of the world's poor," Inter Press Service reports.

5 Dec 2012

Childhood HIV risks becoming neglected disease as fewer children born with HIV, experts warn

"The success in reducing the number of children born with HIV is in danger of leaving children who already have the disease with poor access to treatment, experts in HIV and AIDS have warned," BMJ reports.

4 Dec 2012

Malaria Box helps identify three chemical series that target treatment of NTDs

The Drugs for Neglected Diseases initiative (DNDi) and Medicines for Malaria Venture (MMV) announce today the identification of three chemical series targeting the treatment of deadly neglected tropical diseases (NTDs), through DNDi's screening of MMV's open access Malaria Box.

14 Nov 2012

Financial Times features special report on NTDs

The Financial Times has published a special report on neglected tropical diseases (NTDs) featuring 10 articles examining issues including prevention, research, and treatment.

12 Oct 2012

Grand Challenges Canada funds 15 new projects to improve mental health diagnosis and care

Grand Challenges Canada, which is funded by the Government of Canada, today announced a landmark $19.4 million in support of 15 innovative, pioneering projects designed to improve mental health diagnosis and care in developing countries, many of them nations ravaged by conflict and disaster as well as poverty.

11 Oct 2012

GSK, Aeras to advance clinical development of TB vaccine

Aeras announces that it has signed an agreement with GlaxoSmithKline Vaccines, S.A. (GSK) to jointly advance the clinical development of an investigational tuberculosis (TB) vaccine containing GSK's proprietary M72 antigen and AS01E adjuvant.

10 Oct 2012

Combination pill to treat malaria pre-approved by WHO

"A malaria drug made by India's Cipla has been pre-qualified by the World Health Organization (WHO), an important step towards its roll-out across Asia, where millions of people are infected with the mosquito-borne disease every year," Reuters reports.

6 Oct 2012

Funding neglected disease R&D beneficial to Europe, developing countries, report says

In this bulletin from Science Business, Karen Hoehn, vice executive director and director of international affairs at the German Foundation for World Population, highlights "a study by the independent research group Policy Cures, 'Saving Lives and Creating Impact: E.U. Investment in Poverty-Related and Neglected Disease.'"

29 Sep 2012

New partnership to provide access to contraceptives for more than 27M women

A new partnership announced today at the United Nations will make a safe, effective, long-acting, reversible method of contraception available to more than 27 million women in the world's poorest nations.

28 Sep 2012