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Study reveals how tau tangles spread from one brain region to another in Alzheimer's

Alzheimer's disease is a progressive neurodegenerative disorder that slowly impairs memory, affects thinking skills, and eventually interferes with daily functioning.

8 Apr 2026

RNA barcoding maps neural connections with unprecedented resolution

By tagging neurons with molecular "barcodes," researchers mapped connections among thousands of neurons in the mouse brain with unprecedented speed and resolution.

7 Apr 2026

Calcium channel mutations disrupt early brain development and cause epilepsy

Researchers at Baylor College of Medicine have uncovered a previously unrecognized mechanism by which inherited calcium channel mutations disrupt early brain development and predispose children to epilepsy and related cognitive challenges.

3 Apr 2026

Researchers uncover a chain of molecular events behind early brain changes in Alzheimer's

For the millions of people who carry the gene APOE4, the strongest known genetic risk factor for Alzheimer's disease, their brain activity may begin changing long before any memory problems appear.

3 Apr 2026

Researchers settle 60-year debate on the fundamental mechanisms of visual perception

A scientific dispute spanning six decades about fundamental mechanisms of visual perception in mammals has now been settled. Researchers at TUM have succeeded in observing the visual information flow from neuron to neuron.

2 Apr 2026

Where digital holographic microscopy complements fluorescence microscopy

Integrating Digital Holographic Microscopy with fluorescence techniques enhances live-cell imaging, preserving cellular integrity and improving assay accuracy.

From Park Systems 2 Apr 2026

Internal embodiment could be the key to safer AI systems

When a person reaches across a table to pass the salt, their brain is doing something far more complex than recognizing a request and executing a movement.

1 Apr 2026

Molecular switch in neurons found to limit the regrowth of damaged axonal fibers

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that limits the regrowth of damaged axonal fibers.

1 Apr 2026

DNA damage in gray matter neurons linked to MS progression

For decades, multiple sclerosis research has focused on myelin, the insulation around the brain's wiring. Scientists paid less attention to another loss that was happening in parallel: neurons in the cortex, the seat of higher thinking and cognition, were quietly dying.

1 Apr 2026

Scientists use living muscle to reanimate paralyzed organs

What if a technology could reanimate parts of the body that have lost their connection to the brain - like a bladder that can no longer empty due to a spinal cord injury, or intestines that can't push food forward due to Crohn's disease? What if this technology could also send sensations such as hunger or touch back to the brain?

31 Mar 2026

Retinal organoid study identifies pathways and compounds to protect cone cells

Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) and collaborators have identified genetic pathways and compounds capable of protecting cone photoreceptors from the degeneration that underlies conditions like age-related macular degeneration.

30 Mar 2026

APOE4 alters brain immunity and cognition differently in females and males

APOE4 drove sex-specific changes in meningeal immunity, lymphatic drainage, brain lipids, neuroinflammation, and cognition in mouse models, with females showing greater inflammatory and cognitive vulnerability. Suppressing innate immunity improved some cognitive outcomes in female E4/E4 mice but worsened them in male E4/E4 mice, underscoring the need for sex-tailored approaches.

29 Mar 2026

New neural organoid system improves scalability and reproducibility for research

Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields.

27 Mar 2026

Early testosterone surge triggers rare muscle disease

Spinal and Bulbar Muscular Atrophy (SBMA) is a rare inherited disease that causes progressive muscle weakness and wasting in men.

27 Mar 2026

Study identifies rare genetic disorder linked to premature aging and cognition

Scientists at Sanford Burnham Prebys Medical Discovery Institute and an international team of collaborators have defined a new genetic disease marked by premature aging and deficits in brain function.

24 Mar 2026

Mild hypoxia in preterm infants linked to lifelong memory issues

During intensive care after preterm births, babies can experience low oxygen in their tissue and cells-or hypoxia.

23 Mar 2026

Scientists identify new target to slow Huntington’s disease progression

Huntington's disease is a devastating brain disorder that slowly robs people of movement, memory and personality.

23 Mar 2026

Early biomarker predicts cognitive impairment after out-of-hospital cardiac arrest

Routine early measurement of neurofilament light chain could help improve prediction of cognitive impairment after out-of-hospital cardiac arrest, according to a study presented today at ESC Acute CardioVascular Care 2026, the annual congress of the Association for Acute CardioVascular Care (ACVC), a branch of the European Society of Cardiology (ESC).

23 Mar 2026

Study identifies protein biomarker and potential treatment for schizophrenia

Current schizophrenia medications treat symptoms such as hallucinations and delusions, but do little for cognitive symptoms like disorganized thinking or executive dysfunction.

19 Mar 2026

Synaptic wiring reveals neuronal identity without relying on morphology

Recent technological advances facilitate the reconstruction of complete brain connectomes in small organisms and partial connectomes in mammals, involving the mapping of the network of neurons and synaptic connections.

19 Mar 2026