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Investigational drug ameliorates neuronal DNA damage and inflammation in Alzheimer's model

Accumulation of DNA damage in the brain's neurons may contribute to the development of Alzheimer's disease.

8 Jul 2026

New gene therapy strategy uses the brain's own glymphatic transport system for drug delivery

A new study describes a gene therapy strategy that uses the brain's own glymphatic transport system to distribute engineered viral vectors throughout the brain.

8 Jul 2026

Study uncovers genetic clues behind sex differences in Parkinson's disease

New research presented today (Wednesday) at the Federation of European Neuroscience Societies (FENS) Forum 2026 has discovered some of the genetic changes in brain cells that may help to explain why more men than women develop Parkinson's disease.

7 Jul 2026

Study offers insight into how long-term inflammation may contribute to cognitive decline

The King's College London study, published in Nature Communications, offers insight into how long-term inflammation may contribute to cognitive decline in disorders such as Alzheimer's disease, aging, depression, and the lingering neurological effects of viral infections.

7 Jul 2026

Single cocaine exposure causes lasting brain cell changes in mice

Researchers studying the impact of cocaine in mice have found that just one exposure to the drug can create changes in brain cells that persist for at least two weeks.

6 Jul 2026

Study compares different light therapies for treating Alzheimer's disease

The researchers treated 5‑month‑old 5xFAD mice – a model with aggressive amyloid deposition – with 810‑nm light (25 mW/cm² at the scalp, ~6.25 mW/cm² brain dose for CW, and half that for 40‑Hz due to 50% duty cycle) for 10 minutes daily over 37 days.

6 Jul 2026

Study provides new insights into biological processes linked to Huntington’s disease

A study conducted by the Sant Pau Research Institute (IR Sant Pau) and Hospital de Sant Pau has identified for the first time in living individuals a brain pattern related to the tau protein that changes according to the stage of Huntington's disease.

6 Jul 2026

Experimental drug shields nerve cells from damage caused by ALS

Amyotrophic Lateral Sclerosis, or ALS, received widespread awareness in the summer of 2014 thanks to an Ice Bucket Challenge. Millions of people participated in the challenge, drenching themselves in ice cold water to bring visibility to this devastating neurodegenerative disease and generate charitable donations for research.

3 Jul 2026

Prenatal high fructose exposure impairs brain development and memory

Nutritional imbalance during pregnancy can have long-lasting effects on the health status and disease susceptibility of the offspring.

2 Jul 2026

Lung tumors hijack nervous system to drive cancer-related cachexia

According to the Cleveland Clinic, a quarter of cancer deaths can be attributed to one source: cachexia. Cachexia is a syndrome that accompanies underlying chronic illness and causes unwanted muscle and fat loss, reducing quality of life and sometimes even limiting treatment options.

2 Jul 2026

Study reveals hidden brain circuit behind flexible visual thinking

Nuttida Rungratsameetaweemana is challenging a story neuroscience has told for decades. According to the conventional account, our eyes collect raw information and relay it through a series of nerves and waystations that lead deep into the brain, eventually reaching the cortex.

2 Jul 2026

Scientists map how chronic stress alters somatostatin levels in the brain

Consider the brake. Not the engine, which gets all the attention, but the brake, the quiet thing that decides how fast a system is allowed to go.

1 Jul 2026

Sleep protects complex neural networks from drifting into states of permanent instability

Every animal that has ever been studied closely, from the fruit fly to the philosopher, surrenders each day to a state that looks, from the outside, like a small rehearsal for death.

1 Jul 2026

Blood biomarker may predict Alzheimer's progression differently in men

A blood test does not lie, exactly. It reports a number. The question raised by a new mini-review in Brain Medicine, which gathers and weighs a decade of scattered findings, is whether clinicians have been reading the same number in two different ways without realizing it.

30 Jun 2026

Duke engineers grow retinal blood vessel cells from pluripotent stem cells

Biomedical engineers at Duke University have used induced pluripotent stem cells (iPSCs) to grow specialized blood vessel cells critical to retinal health for the first time.

30 Jun 2026

New diagnostic tool bypasses blood-brain barrier to detect autism early

A study published in NeuroMarkers showed that a nanosensor can measure nitric oxide (NO) from patient-derived stem cells to distinguish autism spectrum disorder (ASD) from intellectual disability (ID), even when both conditions share the exact same genetic mutation.

30 Jun 2026

Anti-inflammatory molecule reduces excessive alcohol consumption in female mice

The drugs that keep rheumatoid arthritis in check may one day help people stop drinking. A new Scripps Research study shows that an anti-inflammatory molecule, already approved by the U.S. Food and Drug Administration to treat autoimmune diseases, reduces excessive alcohol consumption in alcohol-dependent female mice.

29 Jun 2026

New drug candidate reduces toxic protein clumps of Huntington's disease

An experimental drug has been shown to alleviate symptoms of Huntington's disease and extend lifespan in mouse models. Further studies are required to determine whether these results may also apply to humans.

29 Jun 2026

Scientists discover how Arc protein spreads Alzheimer's brain pathology

Alzheimer's disease is driven by a buildup of a toxic protein called Tau that kills neurons. As toxic Tau spreads to new regions of the brain, symptoms become worse and ultimately fatal.

29 Jun 2026

Iron overload gradually increases neurons' vulnerability to neurodegeneration

Neurodegenerative diseases affect tens of millions of people worldwide. Among these, Alzheimer's and Parkinson's diseases are the most common; in the United States alone, the Alzheimer's Disease Association and Parkinson's Foundation report roughly 7 million people with Alzheimer's and another million with Parkinson's.

25 Jun 2026