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Novel device uses tiny worms to detect lung cancer cells

Dogs can use their incredible sense of smell to sniff out various forms of cancer in human breath, blood and urine samples.

20 Mar 2022

Study: Targeting astrocytes reduces tau-related brain damage and inflammation in mice

Alzheimer's disease is the most common and best known of the tauopathies, a set of neurodegenerative brain diseases caused by toxic tangles of the protein tau.

18 Mar 2022

Huddersfield researchers demonstrate how coronavirus activates the brain's immune response

Huddersfield researchers were among the first to demonstrate how the induction of brain inflammation accounts for neurological damage in COVID19 patients and now, their findings have been published in a peer-reviewed medical journal.

17 Mar 2022

Impact of B-cell depletion therapy on hospitalized COVID-19 patients

Researchers assessed the clinical outcomes in patients hospitalized with SARS-CoV-2 infections who were previously treated with B-cell depletion therapy.

17 Mar 2022

Penn State professor receives $2.8 million NIH grant to investigate lower jaw development

How the lower jaw - mandible - develops and consequently how and why some developmental birth defects occur is the focus of a five-year, $2.8 million grant to Joan Richtsmeier, distinguished professor of anthropology, Penn State, from the National Institutes of Health's National Institute of Dental & Craniofacial Research.

16 Mar 2022

Acacetin shows potency against SARS-CoV-2 spike protein

Researchers use molecular docking to screen phytocompounds and evaluate their binding affinity with SARS-CoV-2.

15 Mar 2022

Malaria drug could help treat chemotherapy-resistant head and neck cancers

A new study suggests that the malaria drug hydroxychloroquine inhibits pathways that drive resistance to the chemotherapy agent cisplatin in head and neck cancers and restores tumor-killing effects of cisplatin in animal models.

14 Mar 2022

In silico screening of natural ACE2 inhibitors

Researchers identify potential ACE2 inhibitors through a virtual screening protocol.

14 Mar 2022

Researchers develop new cranial window system for long-term studies of brain activity

Bilal Haider is studying how multiple areas of the brain work together for visual perception. This could help researchers understand if neural activity "traffic jams" underlie all kinds of visual impairments: from running a red light when visual attention is elsewhere, to shedding light on the autism-affected brain.

11 Mar 2022

Aminoglycoside antibiotic geneticin shows selective antiviral effect against SARS-CoV-2

Researchers elucidated antiviral activities of aminoglycoside geneticin against seven SARS-CoV-2 variants using different cell lines and respiratory tissues.

11 Mar 2022

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Researchers discovered and optimized cysteine-reactive pyrazoline-based covalent inhibitors for several coronaviruses' Mpro, including SARS-CoV-2.

11 Mar 2022

Active compound in Chinese herbs prevents colon cancer in mice

The active compound in Chinese herbs called emodin can prevent colon cancer in mice, according to researchers at the University of South Carolina School of Medicine.

9 Mar 2022

Researchers exploit cancer cells' appetite for iron to treat tough tumors

Researchers at the University of California, San Francisco, have successfully leveraged an FDA-approved drug to halt growth of tumors driven by mutations in the RAS gene, which are famously difficult to treat and account for about one in four cancer deaths.

9 Mar 2022

New analysis method to identify interacting proteins in a protein degrader-dependent manner

Protein degraders, which induce the protein degradation of target proteins, are expected to be the "next-generation drugs" because they can remove disease-related proteins from cells.

8 Mar 2022

Identification of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding

Researchers discovered compounds able to inhibit SARS-CoV-2 macrodomain 1 and adenosine diphosphate-ribose binding via high throughput screening.

7 Mar 2022

CD4 T-cell immunity active six months into COVID-19 convalescence

A new paper explores the presence of CD4 T-cell-mediated adaptive immunity against SARS-CoV-2 in late convalescence.

6 Mar 2022

Texas A&M team continues research on the potential cure for Menkes disease

A life-saving cure solution for Menkes Disease, a copper deficiency in young children, is at the center of a licensing agreement by the The Texas A&M University System, through the Intellectual Property and Commercialization office of Texas A&M AgriLife Research, and a California-based biopharmaceutical company, Engrail Therapeutics.

3 Mar 2022

Study shows targeting DDX3 with RK-33 reduced the viral load in four isolates of SARS-CoV-2

A new study has focused on developing a novel anti-SARS-CoV-2 therapy using HTA directed against the human host DEAD-box RNA helicase.

3 Mar 2022

World's first Microhub makes spatial context accessible for all

New Mica imaging platform from Leica Microsystems brings previously inaccessible experiments to all life science researchers

From Leica Microsystems GmbH 3 Mar 2022

Discovery provides a more precise picture of the retina's optical properties

Researchers at the National Eye Institute (NEI) have discovered that power-producing organelles in the eye's photoreceptor cells, called mitochondria, function as microlenses that help channel light to these cells' outer segments where it's converted into nerve signals.

2 Mar 2022

Compound News and Research

Novel device uses tiny worms to detect lung cancer cells

Study: Targeting astrocytes reduces tau-related brain damage and inflammation in mice

Huddersfield researchers demonstrate how coronavirus activates the brain's immune response

Impact of B-cell depletion therapy on hospitalized COVID-19 patients

Penn State professor receives $2.8 million NIH grant to investigate lower jaw development

Acacetin shows potency against SARS-CoV-2 spike protein

Malaria drug could help treat chemotherapy-resistant head and neck cancers

In silico screening of natural ACE2 inhibitors

Researchers develop new cranial window system for long-term studies of brain activity

Aminoglycoside antibiotic geneticin shows selective antiviral effect against SARS-CoV-2

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Active compound in Chinese herbs prevents colon cancer in mice

Researchers exploit cancer cells' appetite for iron to treat tough tumors

New analysis method to identify interacting proteins in a protein degrader-dependent manner

Identification of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding

CD4 T-cell immunity active six months into COVID-19 convalescence

Texas A&M team continues research on the potential cure for Menkes disease

Study shows targeting DDX3 with RK-33 reduced the viral load in four isolates of SARS-CoV-2

World's first Microhub makes spatial context accessible for all

Discovery provides a more precise picture of the retina's optical properties

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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