Endocrine News and Research

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Endocrine Society releases new guideline to help diagnose and treat hypothalamic amenorrhea

Female athletes and women who have eating disorders are prone to developing a condition called hypothalamic amenorrhea that causes them to stop menstruating. The Endocrine Society today issued a Clinical Practice Guideline advising healthcare providers on ways to diagnose and treat this condition.

22 Mar 2017

Penn scientists discover method that appears to provide early warning of transplant rejection

Approximately 30,000 organ transplants occur in the United States each year. However, between 20 and 50 percent—depending on the organ type—of the transplanted organs fail within five years, most often because the recipient's immune system attacks, or "rejects," the donated organ.

21 Mar 2017

Scientists identify molecules that may be key to drug resistance in estrogen-driven breast cancers

Three-quarters of all breast cancer tumors are driven by the hormone estrogen. These tumors are frequently treated with drugs to suppress estrogen receptor activity, but unfortunately, at least half of patients do not respond to these treatments, leaving them with drug-resistant tumors and few options.

20 Mar 2017

Circadian misalignments may favor diabetes development

Like almost all light-sensitive living beings, human beings follow biological rhythms set on a period of about 24 hours.

20 Mar 2017

Study: Phthalate exposure during early pregnancy can alter hormone levels in developing fetuses

Exposure during early pregnancy to some phthalates—man-made chemicals commonly found in household plastics, food and personal care products—can have adverse impacts on developing fetuses, according to a new study led by Dr. Sheela Sathyanarayana, a pediatric environmental health specialist at Seattle Children's Research Institute and associate professor at the University of Washington.

16 Mar 2017

Early morning ‘Coffee and Cases’ session seeks to develop clinical skills

The sun is just beginning to rise in the sky as about 25 first- and second-year medical students file into a classroom in Evans Hall.

16 Mar 2017

Whole-body vibration can mimic muscle, bone health benefits of regular exercise in mice

A less strenuous form of exercise known as whole-body vibration can mimic the muscle and bone health benefits of regular exercise in mice, according to a new study published in the Endocrine Society's journal Endocrinology.

16 Mar 2017

Type 2 diabetes can be reversed with intensive medical treatment, study shows

Type 2 diabetes can be reversed with intensive medical treatment using oral medications, insulin and lifestyle therapies, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

15 Mar 2017

Exposure to EDCs alters thyroid hormone signalling, early brain development in frog embryos

Findings published today provide evidence that exposure to endocrine disrupting chemicals (EDCs) causes changes in thyroid hormone signalling, which disturbs brain development.

13 Mar 2017

Hormone secreted by bone cells can suppress appetite, mice study reveals

A hormone secreted by bone cells can suppress appetite, according to mouse studies conducted by Columbia University Medical Center researchers.

8 Mar 2017

Isoflavone consumption linked to decrease in mortality for some breast cancer patients

An epidemiological analysis of data from more than 6,000 American and Canadian women with breast cancer finds that post-diagnosis consumption of foods containing isoflavones—estrogen-like compounds primarily found in soy food—is associated with a 21 percent decrease in all-cause mortality.

6 Mar 2017

Dietary soy products could be safe, beneficial for women diagnosed with breast cancer

New research indicates that dietary soy products are safe and even beneficial for women diagnosed with breast cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings may help resolve controversies over soy's potential link to breast cancer outcomes.

6 Mar 2017

Exercise-induced irisin could regulate bone metabolism by autocrine mechanisms

Two weeks of voluntary wheel running induces higher expression of irisin--a fat-burning hormone that is released during exercise--in bone tissue in mice.

3 Mar 2017

TOXIC COCKTAIL: New book provides insights into how chemical pollution affects brain development

Today, everyone carries a toxic load of industrially-produced chemicals in their bloodstream: pesticides, plasticizers, disinfectant products, flame-retardants, surfactants, and UV filters. These chemicals are harmful to everyone, but they are particularly dangerous to pregnant women and their developing fetuses.

3 Mar 2017

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

A team led by Pr. Marina Cavazzana conducted at Necker Children's Hospital, AP-HP and the Imagine Institute in October 2014 gene therapy in the context of a phase I clinical trial / II in a patient 13 years with severe sickle cell disease.

2 Mar 2017

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

A Japanese research group has discovered that a newly-identified autoimmune endocrine disease that leads to hypopituitarism is caused by thymomas (a type of tumor originating from the thymic gland).

2 Mar 2017

FDA approves new treatment for wide range of patients with Duchenne muscular dystrophy

The U.S. Food and Drug Administration today approved Emflaza (deflazacort) tablets and oral suspension to treat patients age 5 years and older with Duchenne muscular dystrophy (DMD), a rare genetic disorder that causes progressive muscle deterioration and weakness.

9 Feb 2017

Scientists identify beliefs that may influence South Asian patients from taking diabetes medication

The social stigma associated with diabetes and a fear of being poisoned by medical drugs may contribute to patients of South Asian origin failing to take their medication, a new study shows.

8 Feb 2017

New study sheds light on how prenatal BPA exposure increases obesity risk

An expectant mother's exposure to the endocrine-disrupting chemical bisphenol A (BPA) can raise her offspring's risk of obesity by reducing sensitivity to a hormone responsible for controlling appetite, according to a mouse study published in the Endocrine Society's journal Endocrinology.

8 Feb 2017

Study sheds light on role of Armc5 protein in foetal development and T-cell immune responses

Genetic mutations of the Armc5 gene disrupt foetal development and compromise the immune response.

8 Feb 2017

Endocrine News and Research

Endocrine Society releases new guideline to help diagnose and treat hypothalamic amenorrhea

Penn scientists discover method that appears to provide early warning of transplant rejection

Scientists identify molecules that may be key to drug resistance in estrogen-driven breast cancers

Circadian misalignments may favor diabetes development

Study: Phthalate exposure during early pregnancy can alter hormone levels in developing fetuses

Early morning ‘Coffee and Cases’ session seeks to develop clinical skills

Whole-body vibration can mimic muscle, bone health benefits of regular exercise in mice

Type 2 diabetes can be reversed with intensive medical treatment, study shows

Exposure to EDCs alters thyroid hormone signalling, early brain development in frog embryos

Hormone secreted by bone cells can suppress appetite, mice study reveals

Isoflavone consumption linked to decrease in mortality for some breast cancer patients

Dietary soy products could be safe, beneficial for women diagnosed with breast cancer

Exercise-induced irisin could regulate bone metabolism by autocrine mechanisms

TOXIC COCKTAIL: New book provides insights into how chemical pollution affects brain development

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

FDA approves new treatment for wide range of patients with Duchenne muscular dystrophy

Scientists identify beliefs that may influence South Asian patients from taking diabetes medication

New study sheds light on how prenatal BPA exposure increases obesity risk

Study sheds light on role of Armc5 protein in foetal development and T-cell immune responses

Industry Focus eBook - Cell biology (5th edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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