Endocrine News and Research

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BRCA1/2 mutations may alter endometrial, ovarian function

Scientists have detected significant differences in endometrial thickness and hormone levels in women with and without BRCA1/2 mutations that may play a role in cancer susceptibility or development.

22 Oct 2013

Study finds no evidence that stem cell therapy improves vision for children with ONH

A study performed at Children's Hospital Los Angeles found no evidence that stem cell therapy improves vision for children with optic nerve hypoplasia. Their results are reported in the Journal of the American Association for Pediatric Ophthalmology and Strabismus.

22 Oct 2013

Risk for breast cancer: Key prevention awareness tips for young women

Breast cancer prevention needs to become a shared conversation among women of all ages as it can strike at any age, and is generally more aggressive when diagnosed in women under the age of 50. With hopes to spark that discussion, Isabelle Mercier, PhD, a research assistant professor at University of the Sciences, compiled some key prevention awareness tips for young women.

22 Oct 2013

Ultrasound prior to thyroidectomy important for planning surgery

Ultrasound imaging is commonly used to diagnose and evaluate patients with differentiated thyroid cancer, and to determine whether the disease has spread to lymph nodes in the neck that should be removed at the time of thyroidectomy.

17 Oct 2013

BRAF inhibitor vemurafenib effective for patients with papillary thyroid cancer

Mutations in a gene that codes for the enzyme BRAF kinase have been associated with increased risk for papillary thyroid cancer. An early-stage clinical trial of the BRAF inhibitor vemurafenib resulted in either a partial response or stable disease in patients with PTC and BRAF mutations.

17 Oct 2013

Study explores advantages of minimally invasive parathyroidectomy for treating hyperparathyroidism

An open surgical procedure called bilateral neck exploration has been the gold standard operation for treating patients with primary hyperparathyroidism. But the development of a minimally invasive procedure to remove the parathyroid gland now offers a new option.

17 Oct 2013

Cdk5 protein may play crucial role in deadly form of thyroid cancer

A specific protein once thought to exist only in the brain may play a crucial role in a deadly form of thyroid cancer, as well as other cancers, and provide a fresh target for researchers seeking ways to stop its progression, UT Southwestern Medical Center researchers report today in Cancer Cell.

15 Oct 2013

Depression impairs sleep in breast cancer, but being married helps

Women with metastatic breast cancer are more likely to experience sleep disturbances if they are depressed or single, researchers report.

8 Oct 2013

General surgeon receives Distinguished Service Award from ACS

Last night the Board of Regents of the American College of Surgeons (ACS) presented Barbara Lee Bass, MD, FACS, Houston, TX, with the ACS Distinguished Service Award at the Convocation ceremony preceding the official opening of the 2013 Clinical Congress of the American College of Surgeons.

7 Oct 2013

CHOP’s 22q and You Center plays major role in brain and behavior consortium

Genetics experts from The Children's Hospital of Philadelphia (CHOP) are among the top leaders of a major international collaboration researching why patients with chromosome 22q11.2 deletion syndrome have an elevated risk of schizophrenia and other psychiatric illnesses.

4 Oct 2013

UCSD surgeons perform first robotic gastrectomy for gastric cancer treatment

Surgeons at UC San Diego Health System have performed the region's first robotic gastrectomy, a potentially lifesaving procedure to remove a section of the stomach after a diagnosis of gastric cancer. Aided by a da Vinci robot, surgeons remove the diseased tissue, perform a delicate reconstruction and remove local lymph nodes for further testing.

3 Oct 2013

Research on bone-derived hormone could lead to new treatments for memory loss, depression

Researchers from Columbia University Medical Center (CUMC) have found that the skeleton, acting through the bone-derived hormone osteocalcin, exerts a powerful influence on prenatal brain development and cognitive functions such as learning, memory, anxiety, and depression in adult mice.

27 Sep 2013

EDCs pose threat to human health, say endocrine experts

In an editorial published in Endocrinology, a journal of The Endocrine Society, endocrine experts agreed that endocrine-disrupting chemicals pose a threat to human health and to the ecosystems of the earth.

20 Sep 2013

Hyperthyroidism sounds urinary problem alarm

Physicians should be alert to urinary problems in women with hyperthyroidism, say researchers who found an association between the endocrine disorder and bladder pain syndrome/interstitial cystitis.

16 Sep 2013

Tips for parents of children with cancer

September is Childhood Cancer Awareness Month, and Lisa Diller, MD, chief medical officer of Dana-Farber/Boston Children's Cancer and Blood Disorders Center, advises parents to remain positive if their child is among the 12,000 children in the United States diagnosed with cancer each year.

13 Sep 2013

Pancreatic protein essential for maintaining functional state of beta cells

Researchers at the Pediatric Diabetes Research Center (PDRC) at the University of California, San Diego School of Medicine have shown that the pancreatic protein Nkx6.1 - a beta-cell enriched transcription factor - is essential to maintaining the functional state of beta cells.

13 Sep 2013

New open access Journal of Clinical and Translational Endocrinology from Elsevier

Elsevier, a world-leading provider of scientific, technical and medical information products and services, is pleased to announce the launch of a new open access research publication - Journal of Clinical and Translational Endocrinology (JCTE).

12 Sep 2013

Hormonal disorder causes irregular periods among teenage girls

While irregular periods are common among teenage girls, an underlying hormonal disorder may be to blame if this problem persists.

12 Sep 2013

Gender warns of bipolar I disorder risks

Researchers have confirmed several features that differ between men and women with bipolar disorder, which may impact on the course and treatment of the condition.

11 Sep 2013

MicroBiome Therapeutics' NM504 eliminates diarrhea caused by metformin in type 2 diabetes patient

MicroBiome Therapeutics LLC, a biotechnology company developing pharmaceutical and medical food products that shift the human microbiome in specific ways for improved health, today reported publication of a case report suggesting a potentially important new application for its lead product, NM504. NM504 is in clinical development to promote healthy blood glucose levels and metabolic fitness in prediabetic and diabetic populations.

11 Sep 2013