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New platform for gene editing may change the landscape of CRISPR-based therapeutics

A team of researchers at Northwestern University has devised a new platform for gene editing that could inform the future application of a near-limitless library of CRISPR-based therapeutics.

7 Oct 2022

Clinical trials of novel COVID-19 vaccine developed in Brazil to begin soon

Testing on humans of a novel COVID-19 vaccine developed in Brazil will begin this year. It performed well in animal trials, as reported in an article published in August in Nature Communications.

6 Oct 2022

Intranasal vaccine represents an effective broad-spectrum COVID-19 vaccine strategy

Researchers evaluated the efficacy of dNS1-RBD, a novel intranasal COVID-19 vaccine.

6 Oct 2022

Detecting microplastics in human samples

A new study discusses how microplastics exposure to humans can be examined, preventative measures, and future possibilities in microplastics research.

6 Oct 2022

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Researchers engineered biparatopic nanobodies against SARS-CoV-2.

5 Oct 2022

Particle radioactivity enhances PM2.5 toxicity and increases risk of cardiovascular disease mortality

Particle radioactivity, a characteristic of air pollution that reflects the colorless, odorless gas radon found in fine particulate matter (PM2.5) air pollution, enhances PM2.5 toxicity and increases risk of death from cardiovascular disease, especially from heart attack or stroke, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

5 Oct 2022

Multi-organ chip directly measures the biological impact of nanoparticles

What happens when we breathe in nanoparticles emitted by a laser printer, for example? Could these nanoparticles damage the respiratory tract or perhaps even other organs? To answer these questions, Fraunhofer researchers are developing the "NanoCube" exposure device.

5 Oct 2022

Viagra and Cialis may not be suitable candidates for treating dementia, NIH DREAM study shows

Results from the National Institutes of Health's Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study show that sildenafil (Viagra) and tadalafil (Cialis) may not be suitable candidates for treating dementia.

4 Oct 2022

Early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis begins

Enrollment has begun in an early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis (CF) who carry Pseudomonas aeruginosa (P. aeruginosa) in their lungs.

4 Oct 2022

Multiomic comparison shows a reduction in circulating monocytes correlated with persistent post-COVID-19 pulmonary fibrosis

In a new study, researchers identified distinguishing immune features of coronavirus disease 2019 (COVID-19) in patients with late-resolving pulmonary fibrosis (LR COVID-PF) and early-resolving (ER COVID-PF).

4 Oct 2022

Immune cell defect tied to the risk of developing rare bacterial infection

Everyone breathes in Mycobacterium avium complex (MAC) bacteria from time to time, but most people don't get sick.

3 Oct 2022

Fungal involvement in tumors may drive worse cancer outcomes

The presence of some fungal species in tumors predicts - and may even help drive - worse cancer outcomes, according to a study from Weill Cornell Medicine and Duke University researchers.

3 Oct 2022

Brazilian study reveals the effects of SARS-CoV-2 infection on the central nervous system

A Brazilian study published in the journal PNAS describes some of the effects infection by SARS-CoV-2 can have on the central nervous system.

30 Sep 2022

Research may lead to safer ways to care for patients impacted by blood clots

A nanoparticle therapy developed by investigators at University Hospitals (UH) and Case Western Reserve University targets overactive neutrophils, a specific kind of white blood cell, to prevent almost all types of blood clots while causing no increased risk for bleeding.

30 Sep 2022

Simple nasal wash can prevent hospitalization and deaths from COVID-19

Simple nasal washes with mild saline water can prevent hospitalization and deaths from COVID-19, if applied twice daily following a positive diagnosis, according to research led by the US-based Augusta University.

30 Sep 2022

The compositional and functional diversity of the gut fungal microbiome

Researchers assessed the role of gut bacterial microbiome assembly and the gut mycobiome in relation to health, pathology, and clinical applications.

30 Sep 2022

Patients with scleroderma have reduced levels of Cathepsin L

Much of the research on scleroderma, a connective tissue disease that causes scarring, or fibrosis, has focused on the increased number of proteins promoting fibrosis in these patients. A Medical University of South Carolina (MUSC) research team took a different tact and measured the levels of an antifibrotic protein, Cathepsin L, in these patients.

30 Sep 2022

New screening tool accurately identifies patients at high risk of idiopathic pulmonary fibrosis

A new screening tool for electronic medical records accurately identifies patients who are at high risk of having or developing progressive scarring of the lungs, a condition called idiopathic pulmonary fibrosis, according to investigators from Weill Cornell Medicine, NewYork-Presbyterian, the University of Chicago, Brigham and Women's Hospital and Mayo Clinic.

29 Sep 2022

uPAR may be a promising target for therapy in patients with neuroendocrine neoplasms

A novel PET radiotracer can accurately assess the presence of a biomarker that indicates the level of tumor aggressiveness in neuroendocrine neoplasms (NENs).

28 Sep 2022

Study aims to understand how SARS-CoV-2 affects the brain long-term

Researchers formulate a method to identify the molecular and systemic factors linking COVID-19 to short- and long-term neurologic illness.

28 Sep 2022

Lungs News and Research

New platform for gene editing may change the landscape of CRISPR-based therapeutics

Clinical trials of novel COVID-19 vaccine developed in Brazil to begin soon

Intranasal vaccine represents an effective broad-spectrum COVID-19 vaccine strategy

Detecting microplastics in human samples

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Particle radioactivity enhances PM2.5 toxicity and increases risk of cardiovascular disease mortality

Multi-organ chip directly measures the biological impact of nanoparticles

Viagra and Cialis may not be suitable candidates for treating dementia, NIH DREAM study shows

Early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis begins

Multiomic comparison shows a reduction in circulating monocytes correlated with persistent post-COVID-19 pulmonary fibrosis

Immune cell defect tied to the risk of developing rare bacterial infection

Fungal involvement in tumors may drive worse cancer outcomes

Brazilian study reveals the effects of SARS-CoV-2 infection on the central nervous system

Research may lead to safer ways to care for patients impacted by blood clots

Simple nasal wash can prevent hospitalization and deaths from COVID-19

The compositional and functional diversity of the gut fungal microbiome

Patients with scleroderma have reduced levels of Cathepsin L

New screening tool accurately identifies patients at high risk of idiopathic pulmonary fibrosis

uPAR may be a promising target for therapy in patients with neuroendocrine neoplasms

Study aims to understand how SARS-CoV-2 affects the brain long-term

The ultimate guide to lung research tools and protocols eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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