Neurodegenerative Disease News and Research

RSS

Study: Mouse gene uncovers new strategy for treating Alzheimer's disease

A new study reveals that a previously undiscovered mouse gene reduces the two major pathological perturbations commonly associated with Alzheimer's disease (AD). The research, published by Cell Press in the November 12 issue of the journal Neuron, finds that the novel gene interacts with a key cellular enzyme previously linked with AD pathology, thereby uncovering a new strategy for treating this devastating disorder.

12 Nov 2009

Researchers identify mouse gene that reduces the accumulation Alzheimer's plaques and tangles

Investigators at Burnham Institute for Medical Research (Burnham) and colleagues have identified a novel mouse gene (Rps23r1) that reduces the accumulation of two toxic proteins that are major players in Alzheimer's disease: amyloid beta and tau. The amyloid and tau lowering functions of this gene were demonstrated in both human and mouse cells.

12 Nov 2009

Aethlon Medical begins collaborative biomarker program to study neurodegenerative disease

Aethlon Medical, Inc. (OTC Bulletin Board: AEMD) announced today that it has initiated a collaborative biomarker discovery program with the Center for the Study of Traumatic Encephalopathy (CSTE) at Boston University School of Medicine and the Sports Legacy Institute (SLI).

3 Nov 2009

Researchers show Simvastatin prevents Parkinson's disease from progressing further

Simvastatin, a commonly used, cholesterol-lowering drug, may prevent Parkinson's disease from progressing further. Neurological researchers at Rush University Medical Center conducted a study examining the use of the FDA-approved medication in mice with Parkinson's disease and found that the drug successfully reverses the biochemical, cellular and anatomical changes caused by the disease.

30 Oct 2009

CytRx study reveals potential of molecular chaperones in design of anti-aging pharmaceuticals

CytRx Corporation, a biopharmaceutical company and a leader in molecular chaperone regulation technology, today announced that a paper published in the peer-reviewed journal Gerontology concluded that molecular chaperone amplification may represent a “significant strategy” in the future design of anti-aging pharmaceuticals.

29 Oct 2009

CTE cases are misdiagnosed as Alzheimer's disease, says CSTE researchers

The Center for the Study of Traumatic Encephalopathy (CSTE) at Boston University School of Medicine (BUSM) announced today that a recently deceased member of the NFL Hall of Fame suffered from the degenerative brain disease Chronic Traumatic Encephalopathy (CTE) when he died, becoming the 10th former NFL player diagnosed with the disease.

29 Oct 2009

CIRM awards Salk Institute $10.8M grant to develop stem-cell based therapy for Lou Gehrig's Disease

The Salk Institute has been awarded a $10.8 million grant by the California Institute for Regenerative Medicine (CIRM) for translational research focusing on developing a novel stem-cell based therapy for Amyotrophic Lateral Sclerosis (ALS) - or Lou Gehrig's Disease.

29 Oct 2009

Intellectual property covering compounds that have utility in treating SMA licensed

Repligen Corporation announced today that it has entered into an exclusive license agreement with Families of Spinal Muscular Atrophy (FSMA) for intellectual property covering compounds which may have utility in treating Spinal Muscular Atrophy (SMA).

23 Oct 2009

Stemedica completes pre-IND meeting with the FDA concerning allogeneic mesenchymal bone marrow cells

Stemedica Cell Technologies, Inc., a world leader in stem cell research and manufacturing, announced that it completed its pre-IND meeting with the U.S. Food and Drug Administration (FDA) regarding a proposed IND (Investigative New Drug) to evaluate the safety and efficacy of Stemedica's high potency proprietary allogeneic mesenchymal bone marrow-derived stem cells (adult human) as a treatment for ischemic stroke.

20 Oct 2009

NIH awards a $2.2M grant to biochemist for a high-resolution electron microscope

Waltham, MA-Researchers' ability to rapidly detect the macromolecular protein clumps implicated in Alzheimer's and other neurodegenerative diseases will soon get a sizable boost in the lab of biochemist and Howard Hughes Medical Investigator Nikolaus Grigorieff. The National Institutes of Health has just awarded Grigorieff a $2.2 million grant for a second high-resolution electron microscope (EM) in his lab.

8 Oct 2009

HDSA honors outstanding contributors against Huntington's Disease

The Huntington's Disease Society of America (HDSA), will recognize the outstanding contributions to improving the quality of life of people with Huntington's Disease (HD) by several individuals and two organizations at the 13th annual Guthrie Awards Dinner this Thursday.

7 Oct 2009

New software to detect multiple sclerosis before brain damage occurs

Researchers of the Unit for Systems Biology of the University of Jaén, led by Francisco J. Esteban, are developing a software for clinical use to detect multiple sclerosis even before the typical brain damage of this neurodegenerative disease appear. In order to do so, this scientific multidisciplinary team is calculating the fractal dimension of the brain images registered on magnetic resonance imaging.

1 Oct 2009

Gene variant discovery could lead to future glaucoma treatments

An international team, led by researchers from the University of California, San Diego School of Medicine and the National Eye Institute, has discovered gene variants for glaucoma in a black population. The finding could lead to future treatments or a cure for this disease, which leads to blindness in two million Americans each year.

22 Sep 2009

FDA approves Neuralstem's IND for commencing a stem cell trial to treat Amyotrophic Lateral Sclerosis

Neuralstem, Inc. (NYSE Amex: CUR) today announced that the U.S. Food and Drug Administration (FDA) has approved its Investigational New Drug (IND) application to commence a Phase I trial to treat Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's disease) with its spinal cord stem cells.

21 Sep 2009

Alnylam and Medtronic announce pre-clinical research findings from their Huntington’s disease program

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, and Medtronic, Inc. (NYSE: MDT), the world’s leading developer of medical devices, announced today the presentation of new pre-clinical research findings from their Huntington’s disease program at the 2009 World Congress on Huntington’s Disease held September 12-15, 2009 in Vancouver, British Columbia.

15 Sep 2009

Mild cognitive impairment is a risk factor for dementia

Among individuals with mild cognitive impairment, often considered a transitional state between normal cognitive function and Alzheimer's dementia, those who have more difficulties performing routine activities appear more likely to progress quickly to dementia, according to a report in the September issue of Archives of Neurology, one of the JAMA/Archives journals.

15 Sep 2009

Parkinson Society Canada's SuperWalk raises record amount

SuperWalk for Parkinson's raised a record $2.46 million this year. Lauren Collins, star of Degrassi: The Next Generation, unveiled the new look SuperWalk for 2010 at this year's Toronto walk. Collins, left, walked with her mother, Sari, for her father who has had Parkinson's for over 20 years.

14 Sep 2009

Applications invited from scientists for LBD Biomarker Research Award

The Alzheimer's Drug Discovery Foundation (ADDF) and the Lewy Body Dementia Association (LBDA) invite scientists from the biotechnology industry and academia worldwide to apply for a new collaborative research grant award entitled Lewy Body Dementia Biomarker Research Award.

8 Sep 2009

Higher education levels associated with an earlier need for symptomatic treatment of Parkinson's disease

Individuals who have higher levels of education and who are more impaired by Parkinson's disease appear to require treatment for their symptoms earlier than do other patients, according to a report posted online today that will appear in the September print issue of Archives of Neurology, one of the JAMA/Archives journals.

2 Sep 2009

$3 million grant to help Parkinson's Institute and Clinical Center to continue cutting-edge research

The Parkinson's Institute and Clinical Center (PI) is very excited to announce the receipt of a $3 million challenge grant from the Brin Foundation as the lead gift in the PI's $15 million Capital Campaign - "A Campaign to Conquer Parkinson's Disease." The "Challenge" feature of the grant invites individuals, foundations and corporations to partner with the Brin Foundation in support of Parkinson's research.

28 Aug 2009

Neurodegenerative Disease News and Research

Study: Mouse gene uncovers new strategy for treating Alzheimer's disease

Researchers identify mouse gene that reduces the accumulation Alzheimer's plaques and tangles

Aethlon Medical begins collaborative biomarker program to study neurodegenerative disease

Researchers show Simvastatin prevents Parkinson's disease from progressing further

CytRx study reveals potential of molecular chaperones in design of anti-aging pharmaceuticals

CTE cases are misdiagnosed as Alzheimer's disease, says CSTE researchers

CIRM awards Salk Institute $10.8M grant to develop stem-cell based therapy for Lou Gehrig's Disease

Intellectual property covering compounds that have utility in treating SMA licensed

Stemedica completes pre-IND meeting with the FDA concerning allogeneic mesenchymal bone marrow cells

NIH awards a $2.2M grant to biochemist for a high-resolution electron microscope

HDSA honors outstanding contributors against Huntington's Disease

New software to detect multiple sclerosis before brain damage occurs

Gene variant discovery could lead to future glaucoma treatments

FDA approves Neuralstem's IND for commencing a stem cell trial to treat Amyotrophic Lateral Sclerosis

Alnylam and Medtronic announce pre-clinical research findings from their Huntington’s disease program

Mild cognitive impairment is a risk factor for dementia

Parkinson Society Canada's SuperWalk raises record amount

Applications invited from scientists for LBD Biomarker Research Award

Higher education levels associated with an earlier need for symptomatic treatment of Parkinson's disease

$3 million grant to help Parkinson's Institute and Clinical Center to continue cutting-edge research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News