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Pitt, CMU researchers to develop all-in-one implantable device to record neural activity

The brain is a complex organ full of neurons that work together to help us move, feel, think, and more. A multidisciplinary group from the University of Pittsburgh and Carnegie Mellon University is working to expand the amount of information researchers can receive from a neural interface device and received two grants from the National Science Foundation for their collaborative effort.

29 Oct 2019

Patterns of Alzheimer's-related damage differ by subtype and age of onset, study finds

Despite decades of scientific scrutiny, Alzheimer's disease researchers have yet to work out its cause or treatment. Understanding what underlies its three distinct subtypes is thought to be a promising new research avenue.

29 Oct 2019

How the SETD1A gene produces schizophrenia in mice

A new study published in the journal Neuron on October 9, 2019 reports that scientists have unlocked part of the secrets of the SETD1A gene – how mutations in the gene put the individual at risk for the condition.

26 Oct 2019

High-salt diet may trigger dementia

We’ve all heard that taking too much salt can damage your blood vessels, and now a new study published in the journal Nature on October 23, 2019, says it’s true – a diet rich in salt reduces the levels of nitric oxide, which in turn alters the tau protein within the neuron, triggering a fall in cognitive processing by the brain.

24 Oct 2019

Gene linked to schizophrenia likely confers risk for illness

Researchers have discovered in mice how one of the few genes definitively linked to schizophrenia, called SETD1A, likely confers risk for the illness. Mice genetically engineered to lack a functioning version of the enzyme-coding gene showed abnormalities in working memory, mimicking those commonly seen in schizophrenia patients.

24 Oct 2019

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

Neuroscientists at Georgetown University Medical Center say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson's and Alzheimer's diseases, and improves cognitive and motor behavior.

23 Oct 2019

MIT neuroscientists find a way to reverse noise hypersensitivity in mice

People with autism often experience hypersensitivity to noise and other sensory input. MIT neuroscientists have now identified two brain circuits that help tune out distracting sensory information, and they have found a way to reverse noise hypersensitivity in mice by boosting the activity of those circuits.

23 Oct 2019

Taste neurons could be controlling feeding behaviour find researchers

Researchers from the University of California, Riverside used a common fruit fly (Drosophila melanogaster) to find the association between taste neurons and control of feeding behaviours. They noted that if they genetically modulated these flies, they could make them selectively avoid certain chemicals including acids, bitter compounds, salty substances etc. The results of their study appeared in the October issue of the journal Cell Reports.

22 Oct 2019

Immune cells rewire, repair brain while we sleep, study shows

Science tells us that a lot of good things happen in our brains while we sleep - learning and memories are consolidated and waste is removed, among other things.

21 Oct 2019

Salk scientists receive NIH funding to map brain circuitry for movement

A team of Salk scientists led by Professor Martyn Goulding has been awarded $14.3 million over five years by the National Institutes of Health to create a high-resolution atlas of how the mouse brain generates and controls skilled forelimb movements, such as reaching and grasping.

18 Oct 2019

New NIH BRAIN Initiative awards accelerate the pace of neuroscience research

Scientists have been developing astounding new tools for exploring neural circuits that underlie brain function throughout the first five years of the National Institutes of Health's Brain Research through Advancing Innovative Neurotechnologies Initiative.

18 Oct 2019

Neuroscientists to introduce new approach to assess brain damage in Parkinson's patients

TSU neuroscientists and their colleagues from SibSMU plan to introduce a new approach to studying brain damage in patients with Parkinson's disease

18 Oct 2019

Newly introduced BARseq technology can be used to expand the brain map

Cold Spring Harbor Laboratory Professor Anthony Zador has taken the next step in his quest to solve exactly how the brain is wired.

17 Oct 2019

Researchers identify targeted therapy for adolescent patients with neuroblastoma

Mount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who would otherwise have no treatment options, according to a study published in October in Cancer Cell.

17 Oct 2019

Researchers identify neural pathways that underlie hunger-induced changes in taste preferences

Why does everything taste better when we're hungry? According to new findings from the National Institute for Physiological Sciences in Japan, not only does food taste sweeter when our stomachs are rumbling, but bitter food also becomes less difficult to eat--and both effects are moderated by a neural circuit in the hypothalamus.

16 Oct 2019

Scientists decipher assembly line of glutamate receptors

Rapid communication of neurons in the brain, as well as the ability to learn, fundamentally rely on neurotransmitter receptors located in the contact sites of neurons, the synapses. The most important receptors in the mammalian brain are glutamate receptors of the AMPA-type that generate the electrical signal required for fast communication between neurons.

16 Oct 2019

New technique reveals how the brain responds to light signals received by the retina

In recent decades, scientists have learned a great deal about how different neurons connect and send signals to each other. But it's been difficult to trace the activity of individual nerve fibers known as axons, some of which can extend from the tip of the toe to the head.

15 Oct 2019

How dementia spreads: new study says it’s through neural networks

Scientists have found out a way to forecast the spread of brain atrophy, using prior research that shows how brain networks connect with each other to form a continuously linked pathway.

14 Oct 2019

Dementia spreads via synaptic connections between brain networks

In a new study, UC San Francisco scientists used maps of brain connections to predict how brain atrophy would spread in individual patients with frontotemporal dementia, adding to growing evidence that the loss of brain cells associated with dementia spreads via the synaptic connections between established brain networks.

14 Oct 2019

Researchers shed light on abnormal neuronal activities caused by myelin impairment

The neural circuit basis for motor learning tasks when myelination is impaired has been illuminated for the first time by an international collaboration of university research teams.

11 Oct 2019

Neuron News and Research

Pitt, CMU researchers to develop all-in-one implantable device to record neural activity

Patterns of Alzheimer's-related damage differ by subtype and age of onset, study finds

How the SETD1A gene produces schizophrenia in mice

High-salt diet may trigger dementia

Gene linked to schizophrenia likely confers risk for illness

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

MIT neuroscientists find a way to reverse noise hypersensitivity in mice

Taste neurons could be controlling feeding behaviour find researchers

Immune cells rewire, repair brain while we sleep, study shows

Salk scientists receive NIH funding to map brain circuitry for movement

New NIH BRAIN Initiative awards accelerate the pace of neuroscience research

Neuroscientists to introduce new approach to assess brain damage in Parkinson's patients

Newly introduced BARseq technology can be used to expand the brain map

Researchers identify targeted therapy for adolescent patients with neuroblastoma

Researchers identify neural pathways that underlie hunger-induced changes in taste preferences

Scientists decipher assembly line of glutamate receptors

New technique reveals how the brain responds to light signals received by the retina

How dementia spreads: new study says it’s through neural networks

Dementia spreads via synaptic connections between brain networks

Researchers shed light on abnormal neuronal activities caused by myelin impairment

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