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Breakthrough in the treatment of Restless Legs Syndrome

New research published in The Journal of Physiology presents a breakthrough in the treatment of Restless Legs Syndrome.

13 Nov 2018

Advanced AI and big data methods to tackle dementia

Sports concussions, Parkinson's disease, and hormone therapy for cancer - all can have memory loss as symptoms. But do the biochemical processes of each type of memory loss have anything to reveal about the memory loss that is part of Alzheimer's disease?

13 Nov 2018

Higher body mass index could cause depression even without health problems

A largescale genomic analysis has found the strongest evidence yet that being overweight causes depression, even in the absence of other health problems.

13 Nov 2018

Wishes can help pediatric patients to get better over time

Cimone Stills, 15, has a medical condition that has caused her to have multiple seizures a day for most of her life. Specifically, she has treatment-resistant generalized epilepsy because of a genetic variation. Like many patients with such a serious illness, it affects her daily life and as a result, she was diagnosed with clinical depression.

13 Nov 2018

Small-stature in rainforest populations may be linked to cardiac adaptations

African and Asian rainforest hunter-gatherers share short stature, and now an international team of researchers has shown that this is an example of convergent adaptation that may also be linked to changes in cardiac development pathways.

13 Nov 2018

First bifacial molecule can invade double-stranded DNA or RNA

Carnegie Mellon University researchers have developed a synthetic molecule that can recognize and bind to double-stranded DNA or RNA under normal physiological conditions. The molecule could provide a new platform for developing methods for the diagnosis and treatment of genetic conditions.

13 Nov 2018

Study provides new clues to origin and development of multiple sclerosis

Mapping of a certain group of cells, known as oligodendrocytes, in the central nervous system of a mouse model of multiple sclerosis, shows that they might have a significant role in the development of the disease.

12 Nov 2018

Growth and spread of deadly eye tumor suppressed in cells, animals

By comparing genetic sequences in the eye tumors of children whose cancers spread with tumors that didn't spread, Johns Hopkins Medicine researchers report new evidence that a domino effect in cells is responsible for the cancer spreading.

12 Nov 2018

Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Experimenting with lab-grown brain cancer cells, Johns Hopkins Medicine researchers have added to evidence that a shortage of specific tiny molecules that silence certain genes is linked to the development and growth of pediatric brain tumors known as low-grade gliomas.

12 Nov 2018

Research finds strongest evidence yet that obesity causes depression

New research released today from the University of South Australia and University of Exeter in the UK has found the strongest evidence yet that obesity causes depression, even in the absence of other health problems.

12 Nov 2018

Failed DNA repair triggers chromosomal chaos in cancer cells

Researchers have established the trigger for catastrophic events that occur within the chromosomes of cancer cells and lead to cancer cell death.

12 Nov 2018

Cholesterol control revised in the latest AHA/ACC guidelines

The American Heart Association and the American College of Cardiology have released their latest 121 page guidelines on risk assessment and management of high cholesterol for people who are at a greater risk of heart attacks or strokes.

11 Nov 2018

Saliva-based RNA test could improve ability to accurately identify children with ASD

Newly published research shows that a saliva-based biomarker panel and associated algorithm could improve the ability to accurately identify children with autism spectrum disorder (ASD) in its earliest stages, announced Quadrant Biosciences Inc.

9 Nov 2018

Common bacteria that cause foodborne diseases found to be resistant to antibiotics

Brazil's Ministry of Health received reports of 11,524 outbreaks of foodborne diseases between 2000 and 2015, with 219,909 individuals falling sick and 167 dying from the diseases in question.

9 Nov 2018

Cardiovascular and Alzheimer's disease share common genetics in some individuals, study shows

Genetics may predispose some people to both Alzheimer's disease and high levels of blood lipids such as cholesterol, a common feature of cardiovascular disease, according to a new study by an international team of researchers led by scientists at UC San Francisco and Washington University School of Medicine in St. Louis.

9 Nov 2018

Mitochondrial DNA may have strong influence on cellular metabolism and disease susceptibility

About 1.5 billion years ago, tiny visitors came to live inside the cells that later evolved into all plant and animal life -- including humans.

9 Nov 2018

UCI researchers accelerate and simplify directed evolution bioengineering technique

In a process known as directed evolution, scientists reengineer biomolecules to find ones that perform beneficial new functions. The field is revolutionizing drug development, chemical engineering and other applications, but to realize its promise involves painstaking and time-consuming laboratory work.

9 Nov 2018

Newly designed mice emulate severe form of kidney damage in humans with diabetes

Scientists led by Duke-NUS Medical School have designed mice that successfully emulate a severe form of kidney damage in humans with diabetes, called diabetic nephropathy.

9 Nov 2018

ChromDesign project trains budding scientists in 3D architecture of genome

How does the three-dimensional architecture of our genes affect the differentiation of cells and development of diseases? This is the question behind the European Innovation Training Network "ChromDesign- Chromatin and Design".

8 Nov 2018

Salk researchers solve genetic 'whodunnit' for cancer gene

Long thought to suppress cancer by slowing cellular metabolism, the protein complex AMPK also seemed to help some tumors grow, confounding researchers. Now, Salk Institute researchers have solved the long-standing mystery around why AMPK can both hinder and help cancer.

8 Nov 2018