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Study characterizes cisplatin-induced hearing loss in pediatric cancer patients

Cisplatin is one of the most effective chemotherapy agents, used in just under half of pediatric cancer cases.

13 Feb 2021

Scientists characterize genomic profile of 84 pediatric therapy-related myeloid neoplasms

Children treated for cancer with approaches such as chemotherapy can develop therapy-related myeloid neoplasms (a second type of cancer) with a dismal prognosis.

13 Feb 2021

Revolutionary drug combination shows potential for treatment of fatal childhood cancer

Every year around 20 Australian children die from the incurable brain tumor, Diffuse Intrinsic Pontine Glioma (DIPG). The average age of diagnosis for DIPG is just seven years.

13 Feb 2021

Targeted drug combined with immunotherapy prolongs survival in patients with advanced kidney cancer

Patients with advanced kidney cancer, who received a targeted drug combined with a checkpoint-blocker immunotherapy agent had longer survival than patients treated with the standard targeted drug, said an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial.

13 Feb 2021

Akkure Genomics raises €1.2 million to accelerate roll-out of its next-generation clinical trials platform

Akkure Genomics, an Irish digital health scaleup which is developing a disruptive MedTech platform for the global clinical trials industry, has raised just over €1.2 million in a crowdfunding campaign from 318 investors.

13 Feb 2021

New Cochrane Review: Hydroxychloroquine does not reduce deaths from COVID-19

Hydroxychloroquine does not reduce deaths from COVID-19, and probably does not reduce the number of people needing mechanical ventilation, state the authors of a new Cochrane Review.

13 Feb 2021

S.D. governor gives state high marks in handling the pandemic. Are they deserved?

Covid-19 has pushed states to adopt unique approaches to protect their residents, but few have garnered as much scrutiny as South Dakota.

12 Feb 2021

Active lifestyle associated with lower risk of death from a heart attack

An active lifestyle is linked with a lower chance of dying immediately from a heart attack, according to a study published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology.

12 Feb 2021

A novel approach to suppress the growth of glioblastoma cells

Inhibiting a key enzyme that controls a large network of proteins important in cell division and growth paves the way for a new class of drugs that could stop glioblastoma, a deadly brain cancer, from growing.

12 Feb 2021

$1 million funding for Australian-first plan to boost primary care research

An Australian-first plan to boost primary care research and drive improved patient outcomes, has been backed by $1 million in grant funding.

12 Feb 2021

Lessons learnt from the annual influenza season

Australian researchers have come up with two key recommendations from studies of the annual influenza season - one highlighting the benefits of antivirals in reducing repeat hospitalisation, and the other to watch for underlying cardiovascular disease.

12 Feb 2021

Study reveals detailed map of glioblastoma in genetic, molecular detail

Glioblastoma is among the most aggressive and devastating of cancers. While rare compared with other cancers, it's the most common type of brain cancer.

12 Feb 2021

Reparations before COVID-19 pandemic could have reduced infections, deaths in the U.S.

Civil rights activists have long called for monetary reparations to the Black descendants of Africans enslaved in the United States as a financial, moral, and ethical form of restitution for the injustices of slavery.

12 Feb 2021

Study addresses multiple challenges of the pathogenesis of Huntington's disease

Recent genetic data from patients with Huntington's disease (HD) show that DNA repair is an important factor that determines how early or late the disease occurs in individuals who carry the expanded CAG repeat in the HTT gene that causes HD.

12 Feb 2021

Non-symptomatic cases contribute to at least 50% of SARS-CoV-2 infection

A new study out of the University of Chicago has found that during the initial wave of the COVID-19 outbreak in New York City, only 1 in 5 to 1 in 7 cases of the virus was symptomatic.

11 Feb 2021

Statins shown to reduce COVID-19 severity and lower mortality

Much attention has been focused on ways to reduce the deadly exaggeration of normal inflammatory reactions to this pathogen. A new research paper posted to the medRxiv* preprint server describes the alleviation of hyper-inflammatory phenomena following the administration of statins, drugs more widely known for their use in reducing blood cholesterol levels, to patients with COVID-19.

11 Feb 2021

The impact of SARS-CoV-2 on pregnancy in Nordic countries

Population-based studies are essential to gain knowledge of the spread and management of this disease. However, most studies on pregnancy during COVID-19 have not been broadly applicable to Nordic populations, like most current COVID-19 research in general.

11 Feb 2021

New SARS-CoV-2 variant found in newborn child with seizures in the United States

Researchers at a hospital in Washington D.C. found a new mutant strain of the virus in a neonatal patient with high viral loads. According to the authors, this strain could be spreading in the United States mid-Atlantic population and needs monitoring.

11 Feb 2021

STING activation may be a new approach to reduce graft-versus-host disease

MUSC Hollings Cancer Center researcher Yongxia Wu, Ph.D., identified a new target molecule in the fight against graft-versus-host disease (GVHD).

11 Feb 2021

Use of mobile stroke units linked to improved clinical outcomes

STEMOs (Stroke-Einsatz-Mobile) have been serving Berlin for ten years. The specialized stroke emergency response vehicles allow physicians to start treating stroke patients before they reach hospital.

11 Feb 2021