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Modified herpes simplex virus shows promise in early clinical trial

A virus that has been specifically designed by scientists to be safe to normal tissue but deadly to cancer is showing early promise in a preliminary study, researchers said at the ESMO Conference Lugano (ECLU), Switzerland.

9 Jul 2007

Genome detectives reveal gene suspect for bowel cancer

Scientists in Britain have identified a gene they say increases the risk of bowel cancer by 20%.

8 Jul 2007

Discovery of new gene with links to childhood asthma

New treatments for childhood asthma could be in the pipeline following the discovery of a gene associated with the condition.

5 Jul 2007

Breakthrough new asthma gene found

In a large-scale study conducted with 2,643 children, international researchers with the participation of the Department of Experimental Pneumology of Ruhr-University Bochum (RUB), Germany (Prof. Dr. Albrecht Bufe), have discovered a gene variant that contributes significantly to the risk of childhood asthma.

5 Jul 2007

Study shows inaccuracies in cardiac PET-CT imaging

Current PET-CT scanners with standard commercial software designed to provide images of the heart are falsely indicating coronary artery disease in as many as 40 percent of patients, according to a study published today on the cover page of the Journal of Nuclear Medicine.

4 Jul 2007

Antidepressants not linked to birth defects

Two research studies published in The New England Journal of Medicine found taking SSRIs (selective serotonin reuptake inhibitors), anti-depression drugs, during pregnancy did not significantly increase the overall risk for most birth defects.

4 Jul 2007

Lung cancer patients taking Tarceva who develop a rash fair better

The appearance of a rash in cancer patients treated with erlotinib (Tarceva) is strongly associated with longer survival, according to researchers from the drug's developer, OSI Pharmaceuticals, Inc.

4 Jul 2007

Central command system for pulmonary hypertension discovered

Researchers at the University of Alberta have identified a "central command system" for pulmonary hypertension, a disease that currently has no cure and kills thousands each year.

4 Jul 2007

Are we looking at cancer vaccine trials the wrong way?

Ongoing therapeutic cancer vaccine trials have yet to show evidence of vaccines spurring a patient's immune system to shrink tumors -- yet patients who receive these vaccines in trials tend to live longer and respond better to subsequent treatment.

4 Jul 2007

Variations in two genes related to inflammation may be a risk factor for lung cancer

Variations in two genes related to inflammation may be a major risk factor for developing lung cancer, according to a team of scientists from the National Cancer Institute and the University of Texas M. D. Anderson Cancer Center.

4 Jul 2007

Cardiac surgery in patients with liver cirrhosis

A new study on the outcome of cardiac surgery in patients with liver cirrhosis found that the surgery can safely be performed in patients with milder disease, while those with more severe cirrhosis are less likely to survive.

4 Jul 2007

Biomira files NDA for novel inhibitor of hypoxia-inducible factor-1 alpha

Biomira Inc. has announced that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration for PX-478. PX-478 has been shown in preclinical studies to inhibit hypoxia-inducible factor (HIF)-1 alpha, a protein that controls the transcription of a number of genes whose products are important for tumor growth and survival.

4 Jul 2007

Asthma gene found

A gene that is strongly associated with a risk of developing childhood onset asthma was identified by an international team of scientists, whose findings are published in the journal Nature.

4 Jul 2007

Genetic mutation that may alter response to cancer therapeutics found

Researchers from Eli Lilly & Company and the Phoenix-based Translational Genomics Research Institute (TGen) today announced finding a novel recurring mutation of the gene AKT1 in breast, colorectal and ovarian cancers.

4 Jul 2007

Chocolate lovers rejoice - it lowers the blood pressure!

Chocolate lovers have a good reason to rejoice - new research says dark chocolate helps to keep the blood pressure down.

4 Jul 2007

TB jetsetter not as dangerous as first thought

It seems the jet setting air traveller with tuberculosis (TB) is not quite as dangerous as first thought. According to a federal health official, American lawyer Andrew Speaker has a less severe form of TB than previously diagnosed.

4 Jul 2007

Skin rash actually signifies better outcomes for pancreatic and lung cancer patients

The appearance of a rash in cancer patients treated with erlotinib (Tarceva) is strongly associated with longer survival, according to researchers from the drug's developer, OSI Pharmaceuticals, Inc.

3 Jul 2007

Rethinking therapeutic cancer vaccine trials

3 Jul 2007

Discovery of method to identify how cancer evades the immune system

One of the fundamental traits of a tumor - how it avoids the immune system - might become its greatest vulnerability, according to researchers from the University of Southern California. Their findings, demonstrated in human breast and colorectal cancers, indicate that a technique for determining a tumor's "immune signature," could be useful for diagnosing and treating specific cancers.

3 Jul 2007

Embryos screened to reduce the risk of twins

Japanese researchers say women undergoing fertility treatment may soon be able to have their embryos screened to reduce their chances of giving birth to twins.

3 Jul 2007