Lungs News and Research

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Avian influenza and the U.S

If a virulent strain of avian influenza ever struck the U.S. poultry industry, this country probably would fare better than many other nations due to careful biosecurity procedures in force.

9 Oct 2005

Minimally invasive needle breast biopsies and sentinel node biopsies should be performed more routinely than they currently are

Physicians should strive to replace traditional, invasive procedures for diagnosing breast cancer with proven, less-invasive diagnostic methods, according to an international panel of breast cancer experts convened at the Keck School of Medicine of the University of Southern California.

9 Oct 2005

New role for the blood protein serum amyloid P in the body's response to medical materials

Using a technique called proteomics, the researchers identified many of the blood proteins that stick (adsorb) to the surfaces of medical devices. Blood proteins that adsorb to the surfaces of materials unfold and can be recognized by the body, which then mounts a response against the device.

5 Oct 2005

Deadly 1918 Spanish flue virus has been reconstructed and characterized

This research, reported in this week's issue of Science, is part of a larger research initiative being led by Adolfo Garcia-Sastre, PhD, Professor of Microbiology and Peter Palese, PhD, Professor and Chairman of Microbiology at Mount Sinai School of Medicine.

5 Oct 2005

Particular versions of the TGFb1 gene are largely responsible for how badly the illness affects patients' lungs

Subtle differences in other genes -- besides the defective gene known to cause the illness cystic fibrosis -- can significantly modify the inherited disease's severity, a large new multi-center national study has concluded.

5 Oct 2005

PACs should not be used routinely in patients in intensive care units with severe heart failure

The use of a pulmonary artery catheter (PAC) -- a device used for more than 30 years to assess cardiovascular health and to help guide the treatment of critically ill patients -- does not appear to improve outcomes nor confer added risks to patients.

4 Oct 2005

Divalent metal transporter-1 decreases metal-related injury in the lung

Multi-vitamin products, nutritional supplements and parents tout the need for such mineral elements as calcium, zinc, phosphorus, iron and others.

4 Oct 2005

Cancer incidence among women has increased slightly

Overall rates of cancer death for both men and women have declined in the United States, and cancer incidence has remained stable among men. However, overall cancer incidence among women has increased slightly, according to a special article that appears in the October 5 issue of the Journal of the National Cancer Institute.

4 Oct 2005

Americans' risk of dying from cancer continues to decline

The nation's leading cancer organizations report that Americans' risk of dying from cancer continues to decline and that the rate of new cancers is holding steady. The "Annual Report to the Nation on the Status of Cancer, 1975-2002," published in the Oct. 5, 2005, issue of the Journal of the National Cancer Institute, shows observed cancer death rates from all cancers combined dropped 1.1 percent per year from 1993 to 2002.

4 Oct 2005

Hospitalized patients with severe congestive heart failure did not experience a benefit from use of pulmonary artery catheterization

Advances in medical therapy have improved outcomes for many ambulatory patients with heart failure and low ejection fraction (EF; a measure of how much blood the left ventricle of the heart pumps out with each contraction), according to background information in the article.

4 Oct 2005

Researchers identify gene defect in mice that causes cyclical hair loss and skin cancer

Researchers at Jefferson Medical College and at the Wadsworth Center in New York have identified a gene defect in mice resulting in a range of abnormalities, from cyclical hair loss and skin cancer to severe problems in normal skin development.

4 Oct 2005

Discovery of molecular roots of asthma, arthritis, and multiple sclerosis

The molecular roots of inflammatory and autoimmune diseases such as asthma, arthritis, and multiple sclerosis (MS) have been discovered by a team of researchers led by The University of Texas M. D. Anderson Cancer Center. They say their findings may point to ways to effectively treat these diseases - if not stop them before they start.

4 Oct 2005

Role of asymmetric dimethylarginine in damaged blood vessels

A substance found naturally in the blood vessel lining is thought to contribute towards diseases associated with the circulation system, such as heart failure, high blood pressure, stroke and kidney disease.

4 Oct 2005

Gleevec's uses might expand even further

Gleevec (Imatinib) is a representative of the newest generation of cancer drugs. The substance conveys its potent anti-proliferative effect by selectively supressing the tyrosine kinase pathway. The Giessen lung researchers now issue a first report of this substance as a new target therapy for pulmonary hypertension

4 Oct 2005

Johns Hopkins awarded $12 million to study how stem cell therapies can be used to treat hearts damaged by heart attack

Heart specialists at Johns Hopkins Heart Institute have been awarded more than $12 million from the National Heart, Lung, and Blood Institute (NHLBI) to study how stem cell therapies can be used to treat hearts damaged by heart attack or heart failure.

4 Oct 2005

United States has a major weight problem and it will get worse

A large, community-based study -- considered the first study to assess the long-term risk of developing overweight and obesity in adults -- found that over 30 years, nine out of 10 men and seven out of 10 women were overweight or became overweight. In addition, more than one in three were obese or became obese.

4 Oct 2005

Lack of oxygen in body tissues creates a defect of red blood cells that further exacerbates the condition by constricting blood vessels in the lung

What's more, the team demonstrated through studies in people and animals that inhalation of a 'souped up' form of nitric oxide, which targets red blood cells, reverses the blood abnormality to restore normal lung pressure.

3 Oct 2005

Music helps people with chronic obstructive pulmonary disease focus on their breathing

Before the music can begin, the harmonica teacher makes sure everyone is in position. "Sit up straight. Feet on the floor. Try to breathe from the belly," she says.

28 Sep 2005

New Stat1 and interferon findings

By altering a molecule called Stat1, which is involved in cellular immune signaling, scientists have succeeded in making the molecule more responsive and thus more efficient. This old protein with a new twist may eventually be used to improve the body's defense against infection.

28 Sep 2005

Combination HRT appears to double the breast cancer risk in women who smoke

Older women who have smoked for 11 or more "pack years" - the lifetime equivalent of a pack a day for at least 11 years - face a 30 percent to 40 percent increased risk of developing breast cancer as compared to women who've never smoked, according to new findings from researchers at Fred Hutchinson Cancer Research Center.

28 Sep 2005

Lungs News and Research

Avian influenza and the U.S

Minimally invasive needle breast biopsies and sentinel node biopsies should be performed more routinely than they currently are

New role for the blood protein serum amyloid P in the body's response to medical materials

Deadly 1918 Spanish flue virus has been reconstructed and characterized

Particular versions of the TGFb1 gene are largely responsible for how badly the illness affects patients' lungs

PACs should not be used routinely in patients in intensive care units with severe heart failure

Divalent metal transporter-1 decreases metal-related injury in the lung

Cancer incidence among women has increased slightly

Americans' risk of dying from cancer continues to decline

Hospitalized patients with severe congestive heart failure did not experience a benefit from use of pulmonary artery catheterization

Researchers identify gene defect in mice that causes cyclical hair loss and skin cancer

Discovery of molecular roots of asthma, arthritis, and multiple sclerosis

Role of asymmetric dimethylarginine in damaged blood vessels

Gleevec's uses might expand even further

Johns Hopkins awarded $12 million to study how stem cell therapies can be used to treat hearts damaged by heart attack

United States has a major weight problem and it will get worse

Lack of oxygen in body tissues creates a defect of red blood cells that further exacerbates the condition by constricting blood vessels in the lung

Music helps people with chronic obstructive pulmonary disease focus on their breathing

New Stat1 and interferon findings

Combination HRT appears to double the breast cancer risk in women who smoke

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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