Genetic News and Research

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Toddlers with ASD display emotional vulnerabilities signaling risk for affective, behavioral problems

At the time when autism spectrum disorder can be first reliably diagnosed, toddlers affected by ASD are already displaying emotional vulnerabilities potentially foreshadowing the emergence of co-morbid affective and behavioral conditions highly prevalent in older children, reports a study published in the Journal of the American Academy of Child and Adolescent Psychiatry.

7 Nov 2018

Fish-rich and vegetarian diet may reduce hypertension-related heart disease symptoms

Elevated levels of trimethylamine N-oxide--a compound linked with the consumption of fish, seafood and a primarily vegetarian diet--may reduce hypertension-related heart disease symptoms.

7 Nov 2018

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved LORBRENA, a third-generation anaplastic lymphoma kinase tyrosine kinase inhibitor for patients with ALK-positive metastatic non-small cell lung cancer whose disease has progressed on crizotinib and at least one other ALK inhibitor for metastatic disease; or whose disease has progressed on alectinib or ceritinib as the first ALK inhibitor therapy for metastatic disease.

5 Nov 2018

TGen and City of Hope announce letter of intent to develop new cell therapy manufacturing facility

City of Hope, a world-renowned independent cancer research and treatment center, and its affiliate, Translational Genomics Research Institute, have announced a letter of intent to develop a state-of-the-art cell therapy manufacturing facility in the Phoenix Metropolitan Area, a move that would improve the speed at which stem cell research and cancer treatment is delivered.

5 Nov 2018

Genetics can be used to predict schizophrenic patient's response to antipsychotic drugs

Genetics can be used to predict a patient's response to antipsychotic drug treatment for schizophrenia, according to a recent study by investigators at The Feinstein Institute for Medical Research. The findings were published online today in the American Journal of Psychiatry.

5 Nov 2018

Researchers identify genetic variation that may influence severity of CTE disease

Researchers have identified a genetic variation that may influence chronic traumatic encephalopathy disease severity.

5 Nov 2018

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of neurological disease, today announced data demonstrating that genetic inhibition of SARM1 prevents axonal degeneration in the central, ocular and peripheral nervous systems.

5 Nov 2018

Genetic factors linked to obesity may lower metabolic risk

Experts believe that where on the body people store surplus fat, whether round their middle or round the liver, may be genetically determined.

2 Nov 2018

Scientists discover biomarkers for Zika-related birth defects

Scientists at USC have discovered biomarkers for fetal birth defects in the blood of pregnant women infected with Zika.

2 Nov 2018

UCV researchers discover the influence of exosomes on age-related macular degeneration

Researchers of the Neurobiology and Neurophysiology team of the Medicine Faculty at Valencia Catholic University, headed by Jorge Bacia, have discovered that exosomes - microscopic extracellular vesicles that are released by all cells - from the retinal pigment epithelium lead to cases of neovascularization, a finding which could be closely related to similar processes in age-related macular degeneration.

2 Nov 2018

Study reveals how cancer-causing HPVs evolved

Cancer-causing human papillomaviruses diverged from their most recent common ancestors approximately half a million years ago, roughly coinciding with the timing of the split between archaic Neanderthals and modern Homo sapiens, according to a study published November 1 in the open-access journal PLOS Pathogens by Zigui Chen of the Chinese University of Hong Kong, Robert Burk of the Albert Einstein College of Medicine, and colleagues.

2 Nov 2018

Illumina signs agreement to acquire Pacific Biosciences

Illumina, Inc. and Pacific Biosciences today announced they have signed an agreement for Illumina to acquire Pacific Biosciences at a price of $8.00 per Pacific Biosciences share in an all-cash transaction.

2 Nov 2018

C-Path, CHDI and CDISC announce availability of Huntington's Disease Therapeutic Area User Guide

The Huntington's Disease Regulatory Science Consortium, launched in March 2018 by the Critical Path Institute and CHDI Foundation, today, along with the Clinical Data Interchange Standards Consortium, announce the open availability of a newly developed Huntington's Disease Therapeutic Area User Guide

2 Nov 2018

TGen, City of Hope to develop cell therapy manufacturing facility in Phoenix

City of Hope, a world-renowned independent cancer research and treatment center, and its affiliate, Translational Genomics Research Institute (TGen), have announced a letter of intent to develop a state-of-the-art cell therapy manufacturing facility in the Phoenix Metropolitan Area, a move that would improve the speed at which stem cell research and cancer treatment is delivered.

2 Nov 2018

Antibiotic found in dirt can destroy mutant mycobacteria responsible for TB, study suggests

For decades, doctors have been using antibiotics to fight tuberculosis. And consistently, the microbe responsible for the disease, Mycobacterium tuberculosis, has been fighting back. When confronted with current drugs, such as the antibiotic rifamycin, the bacterium often mutates in ways that make it resistant to the treatment.

1 Nov 2018

New form of therapy may stop or reverse progressive vision loss

A new form of therapy may halt or even reverse a form of progressive vision loss that, until now, has inevitably led to blindness.

1 Nov 2018

MCG selected as designated laboratory for NCI-MATCH trial

The Georgia Esoteric and Molecular Laboratory at the Medical College of Georgia at Augusta University has been selected as a designated laboratory for the National Cancer Institute's Molecular Analysis for Therapy Choice, or MATCH trial, which is assessing the effectiveness of targeting cancer-causing gene changes rather than cancer type.

1 Nov 2018

UCLA researchers investigate how a protein factor contributes to cancer cell migration

UCLA researchers have discovered a new protein factor that contributes to a fibroblast cell's ability to migrate to a wound and participate in its healing process. The study's results could help scientists prevent cancer cells from using the same mechanisms to move throughout the body and spread.

1 Nov 2018

Researchers uncover confusion and gaps in study participants’ understanding of genetic privacy

Confusion and ambiguity in how U.S. patients and researchers perceive genetic privacy is uncovered by a study published October 31, 2018 in the open-access journal PLOS ONE by Ellen W. Clayton from Vanderbilt University, USA, and colleagues.

1 Nov 2018

UA scientists aim to identify drug targets for rare pediatric cancer

Rhabdomyosarcoma is a rare cancer of the skeletal muscle that primarily affects pediatric patients. After diagnosis, about 3 out of 4 patients are cured with standard treatment. Survival rates drop to 17 percent if the disease comes back (recurs) and to 30 percent if it spreads (metastasizes).

1 Nov 2018

Genetic News and Research

Toddlers with ASD display emotional vulnerabilities signaling risk for affective, behavioral problems

Fish-rich and vegetarian diet may reduce hypertension-related heart disease symptoms

FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

TGen and City of Hope announce letter of intent to develop new cell therapy manufacturing facility

Genetics can be used to predict schizophrenic patient's response to antipsychotic drugs

Researchers identify genetic variation that may influence severity of CTE disease

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Genetic factors linked to obesity may lower metabolic risk

Scientists discover biomarkers for Zika-related birth defects

UCV researchers discover the influence of exosomes on age-related macular degeneration

Study reveals how cancer-causing HPVs evolved

Illumina signs agreement to acquire Pacific Biosciences

C-Path, CHDI and CDISC announce availability of Huntington's Disease Therapeutic Area User Guide

TGen, City of Hope to develop cell therapy manufacturing facility in Phoenix

Antibiotic found in dirt can destroy mutant mycobacteria responsible for TB, study suggests

New form of therapy may stop or reverse progressive vision loss

MCG selected as designated laboratory for NCI-MATCH trial

UCLA researchers investigate how a protein factor contributes to cancer cell migration

Researchers uncover confusion and gaps in study participants’ understanding of genetic privacy

UA scientists aim to identify drug targets for rare pediatric cancer

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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