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ECMO life-support therapy can increase odds of survival for critically-ill COVID-19 patients

COVID-19 has caused more than 2 million deaths worldwide since the World Health Organization declared it a pandemic in March 2020.

2 Feb 2021

Study finds link between lack of ICU beds and patient mortality during COVID-19 pandemic

A new study by Yale researchers found a significant association between the availability of hospital resources -- particularly ICU beds -- and patient mortality during the early weeks of the COVID-19 pandemic.

2 Feb 2021

Automated method identifies and tracks harmful tau deposits involved in Alzheimer's disease

Amyloid-beta and tau are the two key abnormal protein deposits that accumulate in the brain during the development of Alzheimer's disease, and detecting their buildup at an early stage may allow clinicians to intervene before the condition has a chance to take hold.

2 Feb 2021

Immune dysregulation can affect the efficacy of CAR T therapy in some lymphoma patients

Chimeric antigen receptor T-cell therapy, or CAR T, has been a breakthrough in the treatment of blood cancers such as acute lymphoblastic leukemia and diffuse large B-cell lymphoma.

2 Feb 2021

CoCID project aims to develop soft X-ray microscope for visualizing cellular origin of diseases

CoCID (Compact Cell Imaging Device), a €5.7 million, four-year, pan-European research and innovation project, funded through Horizon 2020, has officially commenced.

2 Feb 2021

Study identifies triggers for acute decompensation of liver cirrhosis

Chronic liver disease and even cirrhosis can go unnoticed for a long time because many patients have no symptoms: the liver suffers silently.

2 Feb 2021

Study examines the link between walnut metabolites and risk of cardiometabolic diseases

Researchers, from the Harvard T.H. Chan School of Public Health in collaboration with investigators from Rovira i Virgili University and the University of Navarra, Spain, used machine learning models, a subset of artificial intelligence, to identify more precisely the components in walnuts that may be responsible for potentially reducing the risk of type 2 diabetes and cardiovascular diseases - two of the leading causes of death in the U.S.

2 Feb 2021

Study shows link between periodontitis and COVID-19 complications

COVID-19 patients are at least three times more likely to experience complications if they also have gum disease, according to research published today in the Journal of Clinical Periodontology, the official publication of the European Federation of Periodontology.

2 Feb 2021

MCRI specialists create Australia's and New Zealand's first set of child head injury guidelines

Australia's and New Zealand's first set of clinical guidelines for children's head injuries has been created by a network of specialists based at the Murdoch Children's Research Institute.

2 Feb 2021

Zinc supplementation bolsters repurposed antivirals against SARS-CoV-2

A new preprint reports the efficacy of two repurposed drugs that could be useful against SARS-CoV-2 when supplemented with zinc.

2 Feb 2021

ACE2 agonist C21 relieves respiratory difficulty in COVID-19

A new study describes a pilot study on the efficacy of a molecule called C21, which enhances the activity of the angiotensin-converting enzyme 2 (ACE2), the host cell receptor that facilitates viral entry.

2 Feb 2021

Game theory used to model the impact of earlier stockpiling and increased PPE storage during COVID-19

Kingston University London researchers have used a mathematical model known as a game theory to explore how the challenge of securing sufficient levels of vital personal protective equipment (PPE) for healthcare workers during the peak of the COVID-19 pandemic could have been mitigated.

2 Feb 2021

Could ultra-low dose radiotherapy treat COVID-19-related pneumonia?

Researchers at the Department of Radiation Oncology, La Milagrosa Hospital, GenesisCare, Madrid, Spain, showed the potential benefit of treating COVID-19 pneumonia with ultra-low doses of radiotherapy.

2 Feb 2021

Differences in immune response to SARS-CoV-2 determine disease severity, study finds

Researchers investigate host responses to SARS-CoV-2, respiratory syncytial virus (RSV), and influenza virus (IV) in the nasal mucosa in children and adults.

2 Feb 2021

Study explores merits and risks of bariatric surgery in younger teens

Obesity and its duration are significant risk factors for type 2 diabetes, cardiovascular events, multiple cancers, and decreased quality of life. According to the Centers for Disease Control and Prevention, obesity affects 20.6% of adolescents ages 12-19 in the United States, meaning a potential lifetime of dealing with this condition.

2 Feb 2021

Intensive BP lowering reduces cardiovascular risk in patients exposed to air pollution

Evidence suggests particulate matter is the air pollutant which poses the greatest threat to global health. Studies have shown that exposure to particulate matter smaller than 2.5 microns is associated with acute and chronic elevations in blood pressure (BP) as well as hypertension.

2 Feb 2021

Researchers discover novel metabolic gatekeeper mechanism for leukemia

In a new study led by Yale Cancer Center, researchers have discovered a novel metabolic gatekeeper mechanism for leukemia.

1 Feb 2021

SARS-CoV-2 triggers development of new-onset IgG autoantibodies in hospitalized COVID-19 patients

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent for coronavirus disease 2019 (COVID-19), is associated with several clinical features common in autoimmune diseases as myalgias, arthralgias, fatigue, and rashes. COVID-19 patients also exhibit less common autoimmunity manifestations such as myositis, thrombosis, myocarditis, encephalitis, vasculitis, and arthritis.

1 Feb 2021

Study explains why people of African descent are less likely to find bone marrow donors

A paper by a multidisciplinary team of scientists affiliated with various Brazilian institutions, including the University of São Paulo (USP) and the National Cancer Institute (INCA), shows that people of African descent are less likely to find a donor in the National Register of Voluntary Bone Marrow Donors (REDOME) than people with predominantly European ancestry.

1 Feb 2021

Urinary shedding of spike protein in COVID-19 patients

A team of scientists from the United States has recently revealed that about 25% of people with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop renal complications and that the viral spike protein can be detected in the urine samples of these patients. The study is currently available on the medRxiv* preprint server.

1 Feb 2021

Hospital News and Research

ECMO life-support therapy can increase odds of survival for critically-ill COVID-19 patients

Study finds link between lack of ICU beds and patient mortality during COVID-19 pandemic

Automated method identifies and tracks harmful tau deposits involved in Alzheimer's disease

Immune dysregulation can affect the efficacy of CAR T therapy in some lymphoma patients

CoCID project aims to develop soft X-ray microscope for visualizing cellular origin of diseases

Study identifies triggers for acute decompensation of liver cirrhosis

Study examines the link between walnut metabolites and risk of cardiometabolic diseases

Study shows link between periodontitis and COVID-19 complications

MCRI specialists create Australia's and New Zealand's first set of child head injury guidelines

Zinc supplementation bolsters repurposed antivirals against SARS-CoV-2

ACE2 agonist C21 relieves respiratory difficulty in COVID-19

Game theory used to model the impact of earlier stockpiling and increased PPE storage during COVID-19

Could ultra-low dose radiotherapy treat COVID-19-related pneumonia?

Differences in immune response to SARS-CoV-2 determine disease severity, study finds

Study explores merits and risks of bariatric surgery in younger teens

Intensive BP lowering reduces cardiovascular risk in patients exposed to air pollution

Researchers discover novel metabolic gatekeeper mechanism for leukemia

SARS-CoV-2 triggers development of new-onset IgG autoantibodies in hospitalized COVID-19 patients

Study explains why people of African descent are less likely to find bone marrow donors

Urinary shedding of spike protein in COVID-19 patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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