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High national prevalence of SARS-CoV-2 with regional variability in England, REACT-1 survey finds

The REACT-1 survey conducted in the United Kingdom demonstrates a high average prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in England during January 2021. The survey also indicates that a sustained reduction in infection prevalence is urgently needed to avoid burden on healthcare systems and reduce coronavirus disease 2019 (COVID-19)-related mortality.

1 Feb 2021

Inhaling unfragmented hyaluronan improves lung function in COPD patients

Researchers at the National Institutes of Health and their collaborators found that inhaling unfragmented hyaluronan improves lung function in patients suffering from severe exacerbation of chronic obstructive pulmonary disease (COPD).

1 Feb 2021

New WHO essential diagnostics list expands the suite of tests to promote better health

To address the lack of access to tests and testing services in multiple countries, WHO since 2018 has published a yearly essential diagnostics list (EDL), a basket of recommended in vitro diagnostics that should be available at point-of-care and in laboratories in all countries to increase timely and life-saving diagnoses.

1 Feb 2021

Study evaluates the performance and acceptability of HPV self-sampling

A study led by Queen Mary University of London has compared the performance and acceptability of a urine test and four different vaginal self-sampling collection devices to detect high risk Human Papilloma Virus (HPV).

1 Feb 2021

Granulocyte changes could help predict patient outcomes in COVID-19

Researchers in Sweden have provided a comprehensive characterization of circulating granulocytes in people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

1 Feb 2021

Adoption of care delivery, cost reduction and quality improvement to improve access to care

The American College of Cardiology's Cardiovascular Summit will feature several poster presentations on care delivery, cost reduction and quality improvement that offer innovative concepts to combat access to care, especially during the ongoing COVID-19 pandemic and as the broader health care system works to improve health equity.

1 Feb 2021

When your chance for a covid shot comes, don’t worry about the numbers

When getting vaccinated against covid-19, there's no sense being picky. You should take the first authorized vaccine that's offered, experts say.

1 Feb 2021

Can metformin reduce mortality in diabetic individuals with severe COVID-19?

A new study by researchers in China and the U.S. describes a round-up of the effects of commonly used hypoglycemic drugs on the outcomes of COVID-19 in diabetic patients.

1 Feb 2021

How a bounty of vaccines flooded a small hospital and its nearby college

When administrators at Hillsdale College, a conservative liberal-arts school in Michigan, heard its local hospital didn't have a way to store the Pfizer-BioNTech covid vaccine, they offered the use of its science department's ultra-low temperature freezer. The vaccine must be stored at minus 94 degrees Fahrenheit.

1 Feb 2021

Older adults without family or friends lag in race to get vaccines

A divide between "haves" and "have-nots" is emerging as older adults across the country struggle to get covid-19 vaccines.

1 Feb 2021

New policy guidance outlines the benefits of Post-Fracture Care Coordination Programs

By 2025 some 500 million people will be living with osteoporosis, a chronic disease which weakens bones and leaves older adults at risk of a fragility fracture - a broken bone which typically occurs after a low-trauma fall. As a result, an estimated 13.5 million fragility fractures will occur worldwide.

1 Feb 2021

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Protein alteration in the family of lamins causes several diseases, known as laminopathies, such as progeria or precocious aging.

1 Feb 2021

Researchers develop mobile EKG device that can identify patients at risk of sudden cardiac death

Researchers from Mayo Clinic and AliveCor Inc. have been using artificial intelligence (AI) to develop a mobile device that can identify certain patients at risk of sudden cardiac death.

1 Feb 2021

Complication of severe SARS-CoV-2 pneumonia results in persistent cortical blindness: Case report

A study recently published in the journal Cureus has described a case report of a coronavirus disease 2019 (COVID-19) patient who presented with pneumonia, posterior reversible encephalopathy syndrome (PRES), and persistent cortical blindness. A detailed clinical presentation of the patient is provided in the report.

31 Jan 2021

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

A phase III study examining whether messenger (m)RNA expression correlated with sensitivity or resistance to chemotherapy did not confer a statistically significant advantage in overall survival for patients with resected stage II-III non-small cell lung cancer (NSCLC), according to research presented at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.

31 Jan 2021

Lung mechanics and hypoxemia in COVID-19 patients with ARDS

To better understand how low blood oxygen level, or hypoxemia, and lung compliance varies in COVIDARDS and how they relate to disease outcomes, researchers developed a dataset of using more than 11,000 COVID-19 patients admitted to the hospital. A research paper published on the medRxiv* preprint server reports their results.

31 Jan 2021

Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression

Researchers at National Taiwan University Hospital in Taipei have conducted a study demonstrating the potential effectiveness of a novel drug combination at reducing morbidity and mortality in coronavirus disease 2019 (COVID-19).

31 Jan 2021

Experts predict 125,000 fewer COVID deaths if 50% of U.S. population initiate vaccination by March 1

A new report combining forecasting and expert prediction data, predicts that 125,000 lives could be saved by the end of 2021 if 50% or more of the U.S. population initiated COVID vaccination by March 1, 2021.

30 Jan 2021

Study reveals effective therapeutic strategy to prevent colorectal cancer progression

Nagoya University researchers and colleagues have revealed that colorectal cancer tissues contain at least two types of fibroblasts (a type of cells found in connective tissue), namely, cancer-promoting fibroblasts and cancer-restraining fibroblasts, and that the balance between them is largely involved in the progression of colorectal cancer.

30 Jan 2021

DSMB recommends continuation of Phase 2/3 study of opaganib for severe COVID-19

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced that the independent Data Safety Monitoring Board (DSMB) for the global Phase 2/3 study of opaganib in patients with severe COVID-19, unanimously recommended to continue the study following a pre-scheduled futility review of unblinded efficacy data from the first 135 patients treated in the study and safety data from the first 175 patients.

30 Jan 2021

Hospital News and Research

High national prevalence of SARS-CoV-2 with regional variability in England, REACT-1 survey finds

Inhaling unfragmented hyaluronan improves lung function in COPD patients

New WHO essential diagnostics list expands the suite of tests to promote better health

Study evaluates the performance and acceptability of HPV self-sampling

Granulocyte changes could help predict patient outcomes in COVID-19

Adoption of care delivery, cost reduction and quality improvement to improve access to care

When your chance for a covid shot comes, don’t worry about the numbers

Can metformin reduce mortality in diabetic individuals with severe COVID-19?

How a bounty of vaccines flooded a small hospital and its nearby college

Older adults without family or friends lag in race to get vaccines

New policy guidance outlines the benefits of Post-Fracture Care Coordination Programs

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Researchers develop mobile EKG device that can identify patients at risk of sudden cardiac death

Complication of severe SARS-CoV-2 pneumonia results in persistent cortical blindness: Case report

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

Lung mechanics and hypoxemia in COVID-19 patients with ARDS

Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression

Experts predict 125,000 fewer COVID deaths if 50% of U.S. population initiate vaccination by March 1

Study reveals effective therapeutic strategy to prevent colorectal cancer progression

DSMB recommends continuation of Phase 2/3 study of opaganib for severe COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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