Therapy News and Research

RSS

Research reveals genomic basis of acute erythroid leukemia

Acute erythroid leukemia is a high-risk cancer with a dismal prognosis, uncertain genetic basis and controversy surrounding the diagnosis. That is changing, thanks to research led by St. Jude Children's Research Hospital that appears today in the journal Nature Genetics.

30 Mar 2019

Research demonstrates clinical utility of ddPCR-powered liquid biopsy at 2019 AACR Annual Meeting

New research demonstrating the clinical utility of Bio-Rad's Droplet Digital PCR powered liquid biopsy will be presented this week during the 2019 American Association for Cancer Research Annual Meeting in Atlanta, March 29-April 3.

30 Mar 2019

New combination therapy found to be well tolerated in patients with aggressive brain tumor

A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients.

30 Mar 2019

Educating doctors alone may not have a noticeable effect on prescribing rates, study shows

Purely educating doctors about the importance of prescribing certain therapies may not be enough to make a meaningful impact, according to a new Penn Medicine study.

29 Mar 2019

FDA approves new oral drug to treat relapsing forms of multiple sclerosis

The U.S. Food and Drug Administration today approved Mavenclad (cladribine) tablets to treat relapsing forms of multiple sclerosis (MS) in adults, to include relapsing-remitting disease and active secondary progressive disease.

29 Mar 2019

WHO guidelines for chronic hepatitis B fail to detect half of the patients in Ethiopia needing treatment

Current World Health Organization (WHO) guidelines for chronic hepatitis B (CHB) fail to detect half of the patients in need of treatment in Ethiopia, report scientists in the Journal of Hepatology, published by Elsevier.

29 Mar 2019

New targetable vulnerability in breast cancer cells discovered

Researchers at the University of Helsinki and Karolinska Institutet have discovered new molecular mechanisms of breast cancer cell signaling that contribute to aggressive behavior of cancer cells.

29 Mar 2019

Queen’s University Belfast and Domainex identify novel first-in-class FLIP inhibitors

Queen’s University Belfast and Domainex are pleased to announce that their joint project team has successfully identified novel first-in-class small molecule inhibitors of the anti-apoptotic protein FLIP.

29 Mar 2019

Johns Hopkins surgeons perform first-ever living donor HIV-to-HIV kidney transplant

For the first time, a person living with HIV has donated a kidney to a transplant recipient also living with HIV. A multidisciplinary team from Johns Hopkins Medicine completed the living donor HIV-to-HIV kidney transplant on Mar. 25. The doctors say both the donor and the recipient are doing well.

29 Mar 2019

Breakthrough study could lead to new treatments for sickle cell disease

In a breakthrough study of sickle cell disease, biomedical engineers in the University of Minnesota College of Science and Engineering have revealed that the building blocks of the disease are much less efficient at organizing than previously thought.

29 Mar 2019

Scientists target metastasis in the battle against cancer

An experimental combination drug therapy attacking the DNA integrity of cancer cells is showing promise for a possible new cancer therapy in the future.

29 Mar 2019

Promising new way to thwart tricky Mtb pathogen

Tuberculosis, an ancient and notoriously difficult disease to treat, has killed millions through the course of human history; and the antibiotics that have been used to fight the disease in recent history are becoming less and less effective.

29 Mar 2019

Columbia receives award for piloting Opioid Education and Naloxone Training on College Campuses

Rachel Shelton, ScD, MPH, Columbia Mailman School of Public Health assistant professor of Sociomedical Sciences, and Lisa Rosen-Metsch, PhD, dean of Columbia University's School of General Studies, received a planning grant award to focus on piloting Opioid Education and Naloxone Training on College Campuses.

29 Mar 2019

Study provides framework for developing Ebola virus therapeutic under FDA Animal Rule

The U.S. Army Medical Research Institute of Infectious Diseases today announced that, for the first time, the U.S. Food and Drug Administration has provided formal regulatory agreement for use of an animal model to support development of a drug candidate, remdesivir, for treating deadly Ebola virus infections.

29 Mar 2019

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most common inherited blood diseases -- sickle cell disease and beta thalassemia -- applying CRISPR-Cas9 gene editing to patients' own blood stem cells.

29 Mar 2019

FDA approves treatment for adults with non-radiographic axial spondyloarthritis

The U.S. Food and Drug Administration today approved Cimzia (certolizumab pegol) injection for treatment of adults with a certain type of inflammatory arthritis called non-radiographic axial spondyloarthritis (nr-axSpA), with objective signs of inflammation. This is the first time that the FDA has approved a treatment for nr-axSpA.

28 Mar 2019

New strategy for potential treatment of HBV associated liver cancer

Researchers from Duke-NUS Medical School, Singapore General Hospital and Lion TCR have demonstrated that they were able to engineer HBV-specific T cells, a type of immune cells found in the body, to treat Hepatocellular carcinoma, a commonly occurring liver cancer.

28 Mar 2019

Tumor biomarker EpCAM shown to be promising target for cancer immunotherapy

Researchers have shown that cancer immunotherapy targeting the tumor biomarker epithelial cell adhesion molecule is safe and nontoxic in mice and can significantly delay tumor formation and growth.

28 Mar 2019

Researchers describe mathematical model as key to developing effective drugs for brain disorders

A collaboration between researchers from the UAB Institute of Neurosciences and the pharmaceutical company GlaxoSmithKline, published in March in Trends in Pharmacological Sciences, describes a mathematical model to quantify the activity of biased G-protein-coupled receptors.

28 Mar 2019

Low-dose radiation therapy may increase uptake of therapeutic nanoparticles by brain tumors

A new study led by Massachusetts General Hospital (MGH) investigators finds that radiation therapy may increase the uptake of therapeutic nanoparticles by glioblastomas, raising the possibility of using both growth-factor-targeted and immune-system-based therapies against the deadly brain tumor.

28 Mar 2019

Therapy News and Research

Research reveals genomic basis of acute erythroid leukemia

Research demonstrates clinical utility of ddPCR-powered liquid biopsy at 2019 AACR Annual Meeting

New combination therapy found to be well tolerated in patients with aggressive brain tumor

Educating doctors alone may not have a noticeable effect on prescribing rates, study shows

FDA approves new oral drug to treat relapsing forms of multiple sclerosis

WHO guidelines for chronic hepatitis B fail to detect half of the patients in Ethiopia needing treatment

New targetable vulnerability in breast cancer cells discovered

Queen’s University Belfast and Domainex identify novel first-in-class FLIP inhibitors

Johns Hopkins surgeons perform first-ever living donor HIV-to-HIV kidney transplant

Breakthrough study could lead to new treatments for sickle cell disease

Scientists target metastasis in the battle against cancer

Promising new way to thwart tricky Mtb pathogen

Columbia receives award for piloting Opioid Education and Naloxone Training on College Campuses

Study provides framework for developing Ebola virus therapeutic under FDA Animal Rule

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

FDA approves treatment for adults with non-radiographic axial spondyloarthritis

New strategy for potential treatment of HBV associated liver cancer

Tumor biomarker EpCAM shown to be promising target for cancer immunotherapy

Researchers describe mathematical model as key to developing effective drugs for brain disorders

Low-dose radiation therapy may increase uptake of therapeutic nanoparticles by brain tumors

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

Latest News