Biochemistry News and Research

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UV light induces new types of DNA damage that may cause malignant melanoma

Studies conducted in yeast show that exposure to ultraviolet light (UV) induces new types of DNA damage that may cause the deadliest form of skin cancer, malignant melanoma.

17 Nov 2020

New technology to diagnose fatal disease in preemies granted FDA's Breakthrough Device Designation

A technology to diagnose a potentially fatal disease in premature infants invented by Sunyoung Kim, PhD, Professor of Biochemistry & Molecular Biology at LSU Health New Orleans School of Medicine, has been granted a Breakthrough Device Designation by the Food and Drug Administration.

16 Nov 2020

New antibody fragment helps reduce Aβ levels in old mice with Alzheimer’s disease

Alzheimer's disease is the most common dementia worldwide and it is characterized by learning impairment, memory loss, disorientation, and anxiety, among other behavioral and psychological symptoms.

16 Nov 2020

Researchers use aerosolized molecules to shut down proteins generated by coronavirus

Researchers at Georgetown University Medical Center have successfully used molecules comprised of small strands of RNA to shut down the production of destructive proteins generated by the COVID-19 virus.

16 Nov 2020

Study: Effect of diabetes medication can be blocked by a molecule from gut bacteria

The action of metformin, the classic drug used to treat diabetes by stabilizing blood sugar, can be blocked by a molecule from the bacteria in our intestines, a University of Gothenburg study shows.

11 Nov 2020

Two paralogous androgen receptor genes control social dominance

Rank in social hierarchy is a condition not solely claimed by humans. In the animal kingdom, male peacocks exhibit brightly colored plumes to illustrate dominance, and underwater, male fish show pops of bright colors to do the same.

11 Nov 2020

How SARS-CoV-2 blocks immune response

An international research team has confirmed the mechanism by which the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). Their article titled, “SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling,” is published in the journal Proceedings of the National Academy of Sciences.

11 Nov 2020

ERC Synergy project explores causes of drug tolerance in intractable fungal infections

Over the next six years, research groups at Charité - Universitätsmedizin Berlin and Tel Aviv University will study how invasive fungal pathogens are able to evade treatments and develop tolerance to antifungal drugs.

10 Nov 2020

Flinders University receives funding for new brain cancer research project

The human brain’s biochemistry may be a stumbling block that has been preventing an effective cure for brain cancer.

10 Nov 2020

Virginia Tech student receives NSERC award to develop minimally invasive treatment for glioblastoma

The Natural Sciences and Engineering Research Council of Canada (NSERC) supports research that results in "breakthrough answers to timeless questions." When choosing awardees, the council looks for creativity and innovation, two qualities they see at the heart of all research advances.

6 Nov 2020

Study may help develop effective drugs against COVID-19

Scientists at the University of Cambridge, in collaboration with Justus-Liebig University, Germany, have uncovered how the genome of SARS-CoV-2 - the coronavirus that causes COVID-19 - uses genome origami to infect and replicate successfully inside host cells.

5 Nov 2020

Researchers pioneer new approach to treating life-threatening snake bites

A new approach of treating life-threatening snake bites responsible for around 100,000 deaths globally each year is being pioneered by an international research consortium led by University of Bristol scientists.

5 Nov 2020

Insulin has met an evolutionary cul-de-sac making most people vulnerable to Type 2 diabetes

Scientists have found that insulin has met an evolutionary cul-de-sac, limiting its ability to adapt to obesity and thereby rendering most people vulnerable to Type 2 diabetes.

5 Nov 2020

Study describes the effects of a DPP3-knockout on the renin-angiotensin system

The role of the enzyme dipeptidyl peptidase 3 in the blood pressure-regulating renin-angiotensin system was investigated in the inter-university cooperation project BioTechMed-Graz. The results could pave the way for new therapies for cardio-renal diseases.

5 Nov 2020

Novel insights on a common protein could have broad biomedical applications

A new University of Colorado Boulder-led study sheds light on a protein key to controlling how cells grow, proliferate and function and long implicated in tumor development.

4 Nov 2020

New, effective CRISPR-based gene drive approach to control transmission of malaria parasites

Employing a strategy known as "population modification," which involves using a CRISPR-Cas9 gene drive system to introduce genes preventing parasite transmission into mosquito chromosomes, University of California researchers have made a major advance in the use of genetic technologies to control the transmission of malaria parasites.

3 Nov 2020

Study finds new clues for disarming antibiotic-resistant bacteria

A virus can stop bacteria from sharing genes for antibiotic resistance among themselves, Texas A&M AgriLife researchers have discovered. The results hint at new ways to treat infections and describe a new feature of a highly diverse, largely unexplored part of the biosphere.

3 Nov 2020

Researchers use new approach to study the mechanisms of cellular uptake of amyloid beta

One of the hallmarks of Alzheimer's disease is the formation of amyloid plaques--sticky clumps of a protein called amyloid beta--that collect between neurons in the brain.

3 Nov 2020

Researchers reveal mechanisms that help C. difficile pathogen to survive in low oxygen levels

Researchers from ITQB NOVA, in collaboration with the Institut Pasteur in Paris, have shed light on the mechanisms that allow Clostridioides difficile, a pathogen that can only grow in oxygen-free environments, to be able to survive low oxygen levels.

3 Nov 2020

Two studies find age as a primary factor in melanoma treatment resistance

Age may cause identical cancer cells with the same mutations to behave differently. In animal and laboratory models of melanoma cells, age was a primary factor in treatment response.

2 Nov 2020

Biochemistry News and Research

UV light induces new types of DNA damage that may cause malignant melanoma

New technology to diagnose fatal disease in preemies granted FDA's Breakthrough Device Designation

New antibody fragment helps reduce Aβ levels in old mice with Alzheimer’s disease

Researchers use aerosolized molecules to shut down proteins generated by coronavirus

Study: Effect of diabetes medication can be blocked by a molecule from gut bacteria

Two paralogous androgen receptor genes control social dominance

How SARS-CoV-2 blocks immune response

ERC Synergy project explores causes of drug tolerance in intractable fungal infections

Flinders University receives funding for new brain cancer research project

Virginia Tech student receives NSERC award to develop minimally invasive treatment for glioblastoma

Study may help develop effective drugs against COVID-19

Researchers pioneer new approach to treating life-threatening snake bites

Insulin has met an evolutionary cul-de-sac making most people vulnerable to Type 2 diabetes

Study describes the effects of a DPP3-knockout on the renin-angiotensin system

Novel insights on a common protein could have broad biomedical applications

New, effective CRISPR-based gene drive approach to control transmission of malaria parasites

Study finds new clues for disarming antibiotic-resistant bacteria

Researchers use new approach to study the mechanisms of cellular uptake of amyloid beta

Researchers reveal mechanisms that help C. difficile pathogen to survive in low oxygen levels

Two studies find age as a primary factor in melanoma treatment resistance

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