Brain Cell News and Research

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Nanoparticle drug delivery shows promise for the future of brain tumour therapy

A nanoparticle drug delivery system designed for brain tumour therapy has shown promising tumour cell selectivity in a novel cell culture model devised by scientists at The University of Nottingham. The project, conducted jointly by the Schools of Pharmacy, Biomedical Sciences and Human Development, will be featured in the September issue of the Experimental Biology and Medicine.

3 Sep 2007

A drug-sensitive 'traffic cop' tells potassium channels to get lost

Our brains are buzzing with electrical activity created by sodium and potassium ions moving in and out of neurons through specialized pores. To prevent the constant chatter from descending into chaos the activity of these ion channels has to be tightly regulated.

3 Sep 2007

Microfluidic chambers advance the science of growing neurons

Researchers at the University of Illinois have developed a method for culturing mammalian neurons in chambers not much larger than the neurons themselves.

30 Aug 2007

Brain's impaired ability to sense glucose might play role in type 2 diabetes

New findings from studies in mice suggest that defects in the brain's ability to respond to glucose play a role in the development of non-insulin dependent (type 2) diabetes, and that a high-fat diet may contribute to impairing brain cells' ability to regulate glucose throughout the body.

30 Aug 2007

Early surgical removal of the ovaries increases a woman's risk of neurological disorders

New research suggests that premenopausal women who have their ovaries removed have an increased risk of developing neurological disorders such as dementia and Parkinsonism.

30 Aug 2007

Binding up iron in the brain to combat Parkinson's and Alzheimer's

Duke University chemists are developing ways to bind up iron in the brain to combat the neurological devastation of Parkinson's and Alzheimer's diseases.

24 Aug 2007

Nanoparticle drug delivery system for brain tumor therapy shows promise

A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists.

24 Aug 2007

Potential new strategies for treating obsessive compulsive disorder

Using genetic engineering, researchers have created an obsessive-compulsive disorder (OCD) - like set of behaviors in mice and reversed them with antidepressants and genetic targeting of a key brain circuit.

24 Aug 2007

Insight into autism's origin in the brain

In the first study of its kind, researchers have discovered that in autistic individuals, connections between brain cells may be deficient within single regions, and not just between regions, as was previously believed.

23 Aug 2007

Vaccine suppresses aggregates of tau protein - implications for Alzheimer's

A new study by NYU Medical Center researchers shows for the first time that the immune system can combat the pathological form of tau protein, a key protein implicated in Alzheimer's disease.

22 Aug 2007

Natural protection provides possible new treatments for stroke

Two substances that occur naturally in the brain act to protect the brain during a stroke. This is the conclusion of a dissertation published at the Sahlgrenska Academy, and the discovery may lead to new treatments for stroke patients.

21 Aug 2007

New prion protein 'Shadoo' discovered - may offer insight into mad cow disease

Scientists have discovered a new protein that may offer fresh insights into brain function in mad cow disease.

17 Aug 2007

HIV protein both causes brain injury and prevents its repair

New evidence reported in the August issue of Cell Stem Cell, a publication of Cell Press, offers a novel perspective on how the HIV/AIDS virus leads to learning and memory deficits, a condition known as HIV-associated dementia.

17 Aug 2007

New insight into fragile X tremor/ataxia syndrome

Researchers have reported new insight into the pathology underlying a recently identified neurological disorder that strikes middle-aged adults that is caused by alterations in the same gene that causes fragile X syndrome.

17 Aug 2007

Overexposure to metals and Alzheimer's disease

A multi-institutional team of researchers led by Emory University has defined for the first time how metal ions bind to amyloid fibrils in the brain in a way that appears toxic to neurons.

7 Aug 2007

Electricity - a new weapon for stalling the progression of cancer

Low-intensity electric fields can disrupt the division of cancer cells and slow the growth of brain tumors, suggest laboratory experiments and a small human trial, raising hopes that electric fields will become a new weapon for stalling the progression of cancer.

3 Aug 2007

Gene variation makes people with depression more likely to respond to the medication citalopram

A variation in a gene called GRIK4 appears to make people with depression more likely to respond to the medication citalopram (Celexa) than are people without the variation, a study by the National Institute of Mental Health (NIMH), part of the National Institutes of Health, has found.

3 Aug 2007

Stem cell therapy rescues motor neurons in ALS model

In a study that demonstrates the promise of cell-based therapies for diseases that have proved intractable to modern medicine, a team of scientists from the University of Wisconsin-Madison has shown it is possible to rescue the dying neurons characteristic of amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder also known as Lou Gehrig's disease.

3 Aug 2007

Autonomous glial mechanism may drive circadian rhythms

Glial cells of the nervous system, once thought to function strictly as support cells for neurons, are now thought to actively modulate them.

2 Aug 2007

Scientists discover brain cell development process implicated in mental retardation

New Brunswick, N.J. , Scientists at Rutgers, The State University of New Jersey, have discovered a biological process in brain cell development that may help explain some causes of mental retardation.

1 Aug 2007