Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

New drug cocktail may show promise in NSCLC patients

A drug approved by the Food and Drug Administration for melanoma in combination with a common cholesterol-lowering drug may show promise in controlling cancer growth in patients with non-small cell lung cancer (NSCLC), according to new research from the Icahn School of Medicine at Mount Sinai.

3 Feb 2016

Researchers use new method to assess quality of colonoscopies performed in outpatient facilities

Colonoscopies are now a routine preventive diagnostic test for millions of Americans each year. While rates are low, complications like perforation, bleeding, and anesthesia-related heart failure can occur. Yale School of Medicine researchers have now developed a quality measure that uses follow-up hospital visits to track the variation in colonoscopy quality among outpatient facilities.

2 Feb 2016

Mount Sinai researchers report new method to restore microbiome of newborns delivered via C-section

Scientists from the Icahn Institute for Genomics and Multiscale Biology at the Icahn School of Medicine at Mount Sinai, collaborating with NYU Langone Medical Center and a multi-center team of researchers, demonstrated for the first time that the microbiome of newborn babies delivered via cesarean section (C-section) can be partially restored to resemble that of vaginally delivered infants.

2 Feb 2016

Allergan and AstraZeneca partner to develop, commercialize ATM-AVI for MBL-producing pathogens

Allergan plc today announced that it has entered into a global agreement with AstraZeneca to develop and commercialize ATM-AVI, an investigational, fixed-dose antibiotic combining aztreonam and avibactam.

30 Jan 2016

Allergan's investigational medication rapastinel granted FDA Breakthrough Therapy designation

Allergan plc., a leading global pharmaceutical company today announced that its Phase III ready investigational medication rapastinel (GLYX-13) received Breakthrough Therapy designation from the U.S. Food and Drug Administration for adjunctive treatment of Major Depressive Disorder (MDD).

29 Jan 2016

10 million of us lack sunshine vitamin

Health pioneers BetterYou have welcomed the views of Nutritionist Marilyn Glenville, that ‘oil based supplements can help you get your recommended dose of vitamin D’.

From BetterYou Ltd 27 Jan 2016

FDA approves Allergan's sNDA to update label for DALVANCE (dalbavancin) for injection

Allergan plc, a leading global pharmaceutical company, today announced the U.S. Food and Drug Administration has approved the company's supplemental new drug application (sNDA) to update the label for DALVANCE (dalbavancin) for injection.

21 Jan 2016

Allergan announces publication of VIBERZI Phase III trial results in The New England Journal of Medicine

Allergan plc announced today the publication of the positive results of the Phase III trials of VIBERZITM C IV (eluxadoline) for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in the January 21 issue of The New England Journal of Medicine.

21 Jan 2016

Endoscopic sleeve gastroplasty treatment may offer new solution for obese patients

In the fight against obesity, bariatric surgery is currently the most effective treatment; however, only 1 to 2 percent of qualified patients receive this surgery due to limited access, patient choice, associated risks and the high costs. A novel treatment method -- endoscopic sleeve gastroplasty -- might offer a new solution for obese patients.

21 Jan 2016

Age of gluten introduction does not reduce risk of celiac disease in at-risk infants

Based on new evidence, the age of introduction of gluten into the infant diet -- or the practice of introducing gluten during breast-feeding -- does not reduce the risk of celiac disease in infants at risk, according to a Position Paper of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition.

20 Jan 2016

Rapastinel demonstrates pro-cognitive benefits in animal model of cognitive impairment

Allergan plc, a leading global pharmaceutical company, announced today that new data on the investigational medication rapastinel (GLYX-13) and its lack of impairment on cognitive function were published in the peer-reviewed journal Behavioural Brain Research.

19 Jan 2016

Mount Sinai Heart starts TANSNIP-PESA study to determine how workplace-based lifestyle intervention reduces CV risk

World-renowned cardiologist Valentin Fuster, MD, PhD, Director of Mount Sinai Heart and Physician-in-Chief of The Mount Sinai Hospital, is undertaking a three-year study, known as the TANSNIP-PESA study, to determine whether a workplace-based lifestyle intervention, accompanied by imaging data, will lead to a reduction in the prevalence of cardiovascular (CV) disease risk factors related to lifestyle.

19 Jan 2016

First trials of smart gas sensing pills offer new clues for development of gut disorder treatments

Researchers have conducted the first ever trials of smart pills that can measure intestinal gases inside the body, with surprising results revealing some unexpected ways that fibre affects the gut.

13 Jan 2016

Minority and ethnic groups diagnosed with colorectal cancer at younger ages

Colorectal cancer is the third most common form of cancer and the second most common cause of cancer deaths in the United States. The chance of developing colorectal cancer increases with age. Now, a study by University of Missouri School of Medicine researchers shows that minority and ethnic groups are being diagnosed with colorectal cancer at younger ages and more advanced stages than non-Hispanic whites.

12 Jan 2016

Chromoendoscopy superior to other surveillance methods in detecting dysplasia in IBD patients

Chromoendoscopy is superior to random biopsy or white-light colonoscopy in detecting dysplasia in patients with inflammatory bowel diseases (IBD), according to a long-term surveillance study led by James F. Marion, MD, Professor of Medicine at Icahn School of Medicine at Mount Sinai, and Director of Education and Outreach at The Susan and Leonard Feinstein Inflammatory Bowel Disease Clinical Center at The Mount Sinai Hospital, published online in the journal Clinical Gastroenterology and Hepatology.

11 Jan 2016

Head-down yoga positions fatal for glaucoma patients

Glaucoma patients may experience increased eye pressure as the result of performing several different head-down positions while practicing yoga, according to a new study published by researchers at New York Eye and Ear Infirmary of Mount Sinai in the journal PLOS ONE.

11 Jan 2016

Largest real world study to date demonstrate effectiveness of biosimilar infliximab in patients with inflammatory bowel diseases who have been switched from reference infliximab

Data from the PRospective Observational cohort Study on patients with Inflammatory bowel disease receiving Therapy with BIOsimilars (PROSIT-BIO) in patients with ulcerative colitis (UC) and Crohn’s disease (CD) has been presented at the Italian Group for the Study of IBD (IG-IBD), VII National Congress, Palermo, Italy.

7 Jan 2016

Palliative care improves care quality, reduces costs for advanced cancer patients with comorbidities

Patients with incurable cancer and numerous other serious health conditions who consulted with a palliative care team within two days of hospitalization had significant savings in hospital costs, according to a new study led by researchers at the Icahn School of Medicine at Mount Sinai.

7 Jan 2016

Naturally occurring changes in brain wiring can help patients avert onset of bipolar disorder

Naturally occurring changes in brain wiring can help patients at high genetic risk of developing bipolar disorder avert the onset of the illness, according to a new study led by researchers at the Icahn School of Medicine at Mount Sinai and published online today in the journal Translational Psychiatry.

6 Jan 2016

UC San Diego School of Medicine study compares payments among different specialties

The Physician Payments Sunshine Act, passed under the Affordable Care Act, requires all pharmaceutical and medical device companies to report payments to physicians, including consulting fees, gifts, speaking fees, meals, travel and research grants. This information is searchable to the public on a database called Open Payments, managed by the Centers for Medicare & Medical Services.

6 Jan 2016

Gastroenterology News and Research

Further Reading

New drug cocktail may show promise in NSCLC patients

Researchers use new method to assess quality of colonoscopies performed in outpatient facilities

Mount Sinai researchers report new method to restore microbiome of newborns delivered via C-section

Allergan and AstraZeneca partner to develop, commercialize ATM-AVI for MBL-producing pathogens

Allergan's investigational medication rapastinel granted FDA Breakthrough Therapy designation

10 million of us lack sunshine vitamin

FDA approves Allergan's sNDA to update label for DALVANCE (dalbavancin) for injection

Allergan announces publication of VIBERZI Phase III trial results in The New England Journal of Medicine

Endoscopic sleeve gastroplasty treatment may offer new solution for obese patients

Age of gluten introduction does not reduce risk of celiac disease in at-risk infants

Rapastinel demonstrates pro-cognitive benefits in animal model of cognitive impairment

Mount Sinai Heart starts TANSNIP-PESA study to determine how workplace-based lifestyle intervention reduces CV risk

First trials of smart gas sensing pills offer new clues for development of gut disorder treatments

Minority and ethnic groups diagnosed with colorectal cancer at younger ages

Chromoendoscopy superior to other surveillance methods in detecting dysplasia in IBD patients

Head-down yoga positions fatal for glaucoma patients

Largest real world study to date demonstrate effectiveness of biosimilar infliximab in patients with inflammatory bowel diseases who have been switched from reference infliximab

Palliative care improves care quality, reduces costs for advanced cancer patients with comorbidities

Naturally occurring changes in brain wiring can help patients avert onset of bipolar disorder

UC San Diego School of Medicine study compares payments among different specialties

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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