Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

AIDS Research Center earns $7.5 million grant renewal

The University of Alabama at Birmingham (UAB) Center for AIDS Research (CFAR) has won a $7.5 million grant to continue its work in the research, prevention and treatment of human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS).

11 Aug 2009

Aethlon Medical tests Hemopurifier against H1N1 virus

Aethlon Medical, Inc. today disclosed that researchers have initiated testing of its Hemopurifier(R) as a candidate treatment against the H1N1 Swine Flu Virus. The Hemopurifier(R) is the first-in-class medical device to selectively adsorb viruses and immunosuppressive toxins from the bloodstream.

10 Aug 2009

New kind of “molecular condom” to protect women from AIDS

University of Utah scientists developed a new kind of “molecular condom” to protect women from AIDS in Africa and other impoverished areas. Before sex, women would insert a vaginal gel that turns semisolid in the presence of semen, trapping AIDS virus particles in a microscopic mesh so they can’t infect vaginal cells.

10 Aug 2009

Defendants in $10.9 million Medicare fraud HIV infusion scheme sentenced to 63 months in prison

Miami physician Keith Russell, 65, and physician's assistant Jorge Luis Pacheco, 50, were each sentenced to 97 months in prison, and physician's assistant Eda Marietta Milanes, 43, was sentenced to 63 months in prison, for their roles in fraud schemes that involved billing Medicare for $10,903,509 worth of unnecessary HIV infusion treatments, Assistant Attorney General Lanny A. Breuer of the Criminal Division; Acting U.S. Attorney Jeffrey H. Sloman of the Southern District of Florida; and Daniel R. Levinson, Inspector General of the Department of Health & Human Services (HHS) announced today.

9 Aug 2009

Novel approach for developing an AIDS vaccine

Researchers at the Yerkes National Primate Research Center, Emory University, believe conventional vaccine strategies should not be the only avenue explored in the development of an effective AIDS vaccine.

7 Aug 2009

Protein DNA repair complex key to avoiding DNA repair mistakes

As the body creates antibodies to fight invaders, a three-protein DNA repair complex called MRN is crucial for a normal gene-shuffling process to proceed properly, University of Michigan research shows.

5 Aug 2009

The extremes of BMI a cause for concern in liver transplantation

A recent study by doctors at the University of Washington explained that patients who are significantly underweight or very severely obese prior to liver transplantation are at increased risk of death following transplantation surgery.

4 Aug 2009

Researchers map how staph infections alter immune system

Infectious disease specialists at UT Southwestern Medical Center have mapped the gene profiles of children with severe Staphylococcus aureus infections, providing crucial insight into how the human immune system is programmed to respond to this pathogen and opening new doors for improved therapeutic interventions.

14 Jul 2009

Cryo-electron tomography shows immature HIV in 3D

Scientists at the European Molecular Biology Laboratory (EMBL) and the University Clinic Heidelberg, Germany, have produced a three-dimensional reconstruction of HIV (Human Immunodeficiency Virus), which shows the structure of the immature form of the virus at unprecedented detail. Immature HIV is a precursor of the infectious virus, which can cause AIDS.

23 Jun 2009

Structure of the HIV protein shell revealed

New research by scientists at The Scripps Research Institute and other institutions provides a close-up look at the cone-shaped shell that is the hallmark of human immunodeficiency virus (HIV), revealing how it is held together - and possible ways to break it apart.

13 Jun 2009

The 'hijacking mechanism' of HIV-1 pinpointed

Researchers at McGill University and the affiliated Lady Davis Institute for Medical Research at Montreal's Jewish General Hospital - along with colleagues at the University of Manitoba and the University of British Columbia - may have found a chink in the armour of the human immunodeficiency virus type 1 (HIV-1), the microorganism which causes AIDS. They have pinpointed the key cellular machinery co-opted by HIV-1 to hijack the human cell for its own benefit.

10 Jun 2009

Antiretroviral therapy earlier yields better clinical outcomes

A clinical trial has demonstrated that HIV-infected adults in a resource-limited setting are more likely to survive if they start antiretroviral therapy (ART) before their immune systems are severely compromised.

9 Jun 2009

Gene transfer technology may lead to an HIV vaccine

A research team may have broken the stubborn impasse that has frustrated the invention of an effective HIV vaccine, by using an approach that bypasses the usual path followed by vaccine developers.

17 May 2009

Chronic infection clearly linked to key immunity protein

The reason deadly infections like human immunodeficiency virus (HIV) and hepatitis C never go away is because these viruses disarm the body's defense system.

15 May 2009

Clues about how blood forms could yield new strategies for treating blood diseases

Biologists have long wondered why the embryonic heart begins beating so early, before the tissues actually need to be infused with blood.

13 May 2009

Caribbean success story - drop in HIV infections in the Dominican Republic

The last decade has seen a sharp drop in HIV infections in the Dominican Republic, resulting largely from reductions in risky sexual behavior, according to a paper in a supplement to the May 1 issue of JAIDS: Journal of Acquired Immune Deficiency Syndromes.

4 May 2009

HIV/AIDS expert urges routine HIV testing

Two influential medical organizations, along with researchers at the University of Alabama at Birmingham (UAB), have announced they strongly recommend universal and routine testing for human immunodeficiency virus (HIV) to help curb the AIDS epidemic. HIV infects more than 30 million globally; during last year alone, more than 2 million worldwide died from AIDS, which is caused by HIV.

3 May 2009

Early initiation of antiretroviral therapy improves HIV survival rates, study says

The New York Times on Thursday examined a study that found asymptomatic HIV-positive people who delayed antiretroviral treatment until their disease reached an advanced stage faced higher mortality rates than those who initiated treatment earlier.

30 Apr 2009

Australian researchers win bumper grant from Bill Gates for HIV research

Australian researchers have won themselves a bumper grant from the Bill & Melinda Gates Foundation to examine the best way of using drugs to treat HIV.

27 Apr 2009

Circumcision reduces risk of contracting HIV without reducing sexual pleasure

Two studies presented at the 104th Annual Scientific Meeting of the American Urological Association (AUA) show that adult circumcision reduces the risk of contracting the human immunodeficiency virus (HIV) and the risk of coital injury without reducing pleasure or causing sexual dysfunction.

26 Apr 2009