Infectious Diseases News and Research

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RARα receptor plays unexpected role in T cell activation

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd - but very important - to help them fight pathogens and destroy cancer cells.

18 Aug 2023

Severe COVID-19 causes long-lasting changes to immune system stem cells

Severe COVID-19 infection triggers changes that affect gene expression in immune system stem cells, causing long-lasting alterations in the body's immune response, according to a new study by Weill Cornell Medicine and Jackson Laboratory investigators.

18 Aug 2023

Medicaid expansion increases cancer clinical trial participation

The Medicaid expansion under the Patient Protection and Affordable Care Act resulted in a 19% annual increase in Medicaid-insured cancer patients participating in publicly funded clinical trials, according to researchers from Fred Hutchinson Cancer Center, the SWOG Statistics and Data Management Center and Columbia University.

18 Aug 2023

Immune cells present in people months before influenza infection, finds study

St. Jude Children's Research Hospital scientists, in collaboration with the Institute of Environmental Science and Research (ESR) Limited, found that immune cells present in people months before influenza (flu) infection could more accurately predict if an individual would develop symptoms than current methods which primarily rely on antibody levels.

18 Aug 2023

New findings could develop effective vaccines or treatments for chikungunya fever

Researchers at Albert Einstein College of Medicine have found that the virus responsible for chikungunya fever can spread directly from cell to cell - perhaps solving the longstanding mystery of how the virus, now emerging as a major health threat, can manage to escape antibodies circulating in the bloodstream.

18 Aug 2023

Databases, techniques for variant forecasting and early warning of emerging infectious diseases

The coronavirus disease 2019 (COVID-19) pandemic has dramatically increased the awareness of emerging infectious diseases.

17 Aug 2023

STING gene variant linked to increased risk of severe group A strep infections

Group A streptococci are fairly common bacteria that can cause, among other things, strep throat or impetigo.

17 Aug 2023

Wristbands can harbor harmful bacteria, study finds

The COVID-19 pandemic took disinfecting to new heights. Now, a new study examining a commonly used item might convince you not to let your guard down just yet.

16 Aug 2023

Most infants admitted to ICU for RSV were previously healthy, study finds

Most infants admitted to the intensive care or high acuity unit for respiratory syncytial virus (RSV) infections during fall 2022 were previously healthy and born at term, according to a new study reported in JAMA Network Open.

16 Aug 2023

Human challenge trials: A game-changer in vaccine development? Examining their role in shaping the pandemic response

The history of using human challenge trials in developing vaccines.

15 Aug 2023

UAB researchers identify cell-surface marker that indicates fate of T cells

Follicular helper T cells, or Tfh cells, have a crucial role in immune defense. Without Tfh cells, B cells cannot form germinal center, or GC, responses during which high-affinity antibodies are generated.

14 Aug 2023

New insights into how coronaviruses invade cells

Unexpected new insights into how COVID-19 infects cells may help explain why coronaviruses are so good at jumping from species to species and will help scientists better predict how COVID-19 will evolve.

14 Aug 2023

Advanced maternal age increases the risk of maternal mortality in Japan

Researchers investigate the relationship between advanced maternal age and maternal mortality in Japan.

14 Aug 2023

Significant association found between the rs1205 T-Dom genotype and risk of COVID-19 death or hospitalization among American Indians

Researchers identify an association between the C-reactive protein gene variant rs1205 and COVID-19 severity.

14 Aug 2023

Parents and clinicians reach consensus on pediatric decision-making

How should others make decisions for pediatric patients? For decades, there has been debate in academic literature about the ethical principles that govern medical decision-making for children.

11 Aug 2023

Scientists leverage machine learning and AI to guide vaccine development

From tackling homework challenges to drafting emails, people are discovering a vast array of applications for natural language processing tools like generative artificial intelligence (AI) engines.

11 Aug 2023

COVID-19 mRNA vaccine or booster during pregnancy benefits mother and baby, study finds

Receiving a COVID-19 mRNA vaccine or booster during pregnancy can benefit pregnant people and their newborn infants, according to findings recently published in Vaccine.

11 Aug 2023

Discontinuation of pandemic-related food assistance benefits led to substantial increase in food insufficiency in the U.S.

The recent discontinuation of pandemic-related food assistance benefits, known as the Supplemental Food Assistance Program (SNAP) Emergency Allotments, led to a substantial increase in food insufficiency in the United States, according to a new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania.

11 Aug 2023

COVID-19 lockdown may have led to waning immunity to gastrointestinal viruses

Following the first stay-at-home orders issued in the U.S. to curb the spread of COVID-19, gastrointestinal viruses such as norovirus, rotavirus and adenovirus all but disappeared from California communities, and remained at very low levels for nearly 2 years.

11 Aug 2023

A third dose boosted cross-protection against SARS-CoV-2 viral variants, finds study

Transplant recipients must take life-long immunosuppressive medications to prevent rejection, but these drugs can compromise the effectiveness of vaccines.

11 Aug 2023

Infectious Diseases News and Research

RARα receptor plays unexpected role in T cell activation

Severe COVID-19 causes long-lasting changes to immune system stem cells

Medicaid expansion increases cancer clinical trial participation

Immune cells present in people months before influenza infection, finds study

New findings could develop effective vaccines or treatments for chikungunya fever

Databases, techniques for variant forecasting and early warning of emerging infectious diseases

STING gene variant linked to increased risk of severe group A strep infections

Wristbands can harbor harmful bacteria, study finds

Most infants admitted to ICU for RSV were previously healthy, study finds

Human challenge trials: A game-changer in vaccine development? Examining their role in shaping the pandemic response

UAB researchers identify cell-surface marker that indicates fate of T cells

New insights into how coronaviruses invade cells

Advanced maternal age increases the risk of maternal mortality in Japan

Significant association found between the rs1205 T-Dom genotype and risk of COVID-19 death or hospitalization among American Indians

Parents and clinicians reach consensus on pediatric decision-making

Scientists leverage machine learning and AI to guide vaccine development

COVID-19 mRNA vaccine or booster during pregnancy benefits mother and baby, study finds

Discontinuation of pandemic-related food assistance benefits led to substantial increase in food insufficiency in the U.S.

COVID-19 lockdown may have led to waning immunity to gastrointestinal viruses

A third dose boosted cross-protection against SARS-CoV-2 viral variants, finds study

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