Kidney Failure News and Research

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Eating disorders a growing problem in U.S.

The number of men and women hospitalized due to eating disorders that caused anemia, kidney failure, erratic heart rhythms or other problems rose 18 percent between 1999 and 2006, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

5 Apr 2009

Novel hemodialysis procedure improves health of cancer patients

A novel hemodialysis procedure helps restore kidney function and increases lifespan in patients with multiple myeloma, according to a study appearing in the April 2009 issue of the Clinical Journal of the American Society Nephrology (CJASN).

1 Apr 2009

Accurate assessment of heart disease leads to earlier, more aggressive therapy

In a study comparing the ability of various medical techniques to accurately determine the extent of heart disease and stratify patients according to disease severity, researchers found that myocardial perfusion testing with gated single photon emission computed tomography (gated SPECT) was a more accurate predictor of prognosis in chronic ischemic heart disease (IHD)-a painful condition caused by a temporary reduction of oxygen-rich blood to the heart.

1 Apr 2009

Dapagliflozin trial results indicate improvement in key glycemic measures in treatment-naive type 2 diabetes

Findings published in Diabetes Care from a 12-week, Phase IIb dose-ranging study showed that dapagliflozin, a novel, selective, sodium glucose co-transporter2 (SGLT2) inhibitor, produced clinically meaningful reductions across all key glycemic measures studied [glycosylated hemoglobin level (HbA1c), fasting plasma glucose (FPG), and postprandial plasma glucose (PPG)] in treatment-naive type 2 diabetes patients, compared to placebo.

29 Mar 2009

Amicus Therapeutics presents positive results from phase 2 extension study of Amigal for Fabry disease

Amicus Therapeutics has announced positive results from its ongoing Phase 2 extension study of its investigational drug, Amigal (migalastat HCL) for Fabry disease.

29 Mar 2009

Anti-microbial catheter to cut infection risk for dialysis patients

Medical experts at The University of Nottingham have shown that an innovative anti-microbial catheter could vastly improve treatment and the quality of life for many community-based dialysis patients.

24 Mar 2009

Set of criteria help identify candidates for combined heart and kidney transplants

Researchers have identified a set of criteria that, when combined with a measure of kidney function, could help identify patients who are likely to receive a survival benefit from a combined heart and kidney transplant, according to a report in the March issue of Archives of Surgery.

16 Mar 2009

Discovery of master switch that might prevent cancer cells from metastasizing

Researchers at the University of Pennsylvania School of Medicine have identified a master switch that might prevent cancer cells from metastasizing from a primary tumor to other organs.

16 Mar 2009

Blocking the dual leucine zipper kinase gene may help ease painful nerve condition

Scientists have identified the first gene that pulls the plug on ailing nerve cell branches from within the nerve cell, possibly helping to trigger the painful condition known as neuropathy.

15 Mar 2009

Study of Rituxan (rituximab) in lupus nephritis misses primary endpoint

Genentech, Inc. and Biogen Idec has announced that a Phase III study of Rituxan (rituximab) plus mycophenolate mofetil (MMF) and corticosteroids in patients with lupus nephritis did not meet its primary endpoint of significantly reducing disease activity at 52 weeks.

11 Mar 2009

Heart attack outcomes worse for blacks than whites due in part to individual characteristics

Black heart attack patients have worse outcomes than their white counterparts in large part because of preexisting chronic health conditions and socioeconomic factors, according to a study published in the March issue of Annals of Internal Medicine, Reuters Health reports.

4 Mar 2009

Revealing statistics about childhood diabetes reported

The incidence rate of type 1 diabetes among non-Hispanic white youth in the United States is one of the highest in the world, according to a major national study coordinated by researchers at Wake Forest University Baptist Medical Center.

1 Mar 2009

Updated formula measures kidney function more accurately

Measuring kidney function in children can be expensive, time-consuming for clinicians, and tedious for children, who may be exposed to radioactivity and subjected to a large number of blood draws.

24 Feb 2009

Children with hypertension have trouble with goal-directed tasks

Children with high blood pressure are not as good at complicated, goal-directed tasks, have more working memory problems and are not as adept at planning as their peers without hypertension, according to recent research.

24 Feb 2009

Updated formula measures kidney function more accurately

Measuring kidney function in children can be expensive, time-consuming for clinicians, and tedious for children, who may be exposed to radioactivity and subjected to a large number of blood draws.

24 Feb 2009

Kidney disease affects response to anticoagulant drug warfarin

Patients with reduced kidney function require lower doses of the anticoagulant drug warfarin, and may need closer monitoring to avoid serious bleeding complications, suggests a study in the April 2009 issue of the Journal of the American Society of Nephrology ( JASN ).

20 Feb 2009

GlaxoSmithKline starts phase III trial of Syncria (albiglutide) type 2 diabetes medication

GlaxoSmithKline has announced initiation and dosing of the first patient of the Phase III clinical trial programme to evaluate the efficacy, safety and tolerability of the investigational GLP-1 (Glucagon-like peptide 1) agonist Syncria (albiglutide) in men and women with type 2 diabetes.

18 Feb 2009

Common gene variants increase risk of hypertension, may lead to new therapies

A new study has identified the first common gene variants associated with an increased incidence of hypertension - a significant risk factor for heart attack, stroke and kidney failure.

16 Feb 2009

Candesartan cilexetil reduces proteinuria in kidney disease patients

Taking a much higher than recommended dose of the hypertension drug candesartan cilexetil effectively lowered the amount of protein excreted in the urine of patients with kidney disease, according to a study appearing in the April 2009 issue of the Journal of the American Society Nephrology ( JASN ).

11 Feb 2009

Kidney damage causes high blood pressure

Doctors have long believed that high blood pressure directly caused kidney damage.

8 Feb 2009

Kidney Failure News and Research

Eating disorders a growing problem in U.S.

Novel hemodialysis procedure improves health of cancer patients

Accurate assessment of heart disease leads to earlier, more aggressive therapy

Dapagliflozin trial results indicate improvement in key glycemic measures in treatment-naive type 2 diabetes

Amicus Therapeutics presents positive results from phase 2 extension study of Amigal for Fabry disease

Anti-microbial catheter to cut infection risk for dialysis patients

Set of criteria help identify candidates for combined heart and kidney transplants

Discovery of master switch that might prevent cancer cells from metastasizing

Blocking the dual leucine zipper kinase gene may help ease painful nerve condition

Study of Rituxan (rituximab) in lupus nephritis misses primary endpoint

Heart attack outcomes worse for blacks than whites due in part to individual characteristics

Revealing statistics about childhood diabetes reported

Updated formula measures kidney function more accurately

Children with hypertension have trouble with goal-directed tasks

Updated formula measures kidney function more accurately

Kidney disease affects response to anticoagulant drug warfarin

GlaxoSmithKline starts phase III trial of Syncria (albiglutide) type 2 diabetes medication

Common gene variants increase risk of hypertension, may lead to new therapies

Candesartan cilexetil reduces proteinuria in kidney disease patients

Kidney damage causes high blood pressure

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