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Reinfections with Omicron VOCs occur more frequently and over shorter intervals

In a recent study published in Nature's Communications Biology journal, researchers in the United States of America (USA) employed next-generation sequencing (NGS) data to assess the rise in reinfections with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant.

23 Mar 2023

Menin protein protects against aging and cognitive decline

In a recent study published in the journal PLoS Biology, researchers from the University of Xiamen, China, explored the role of the hypothalamic menin in driving aging and associated cognitive decay.

23 Mar 2023

Monovalent vs. bivalent vaccines – Which is more effective against SARS-CoV-2?

In a recent study posted to the medRxiv* preprint server, researchers in France compared the efficacy of Pfizer-BioNTech Original/BA.4-5 bivalent vaccine compared to messenger ribonucleic acid (mRNA) Original (ancestral) monovalent vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Mar 2023

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

In a recent study published in the journal PLOS Pathogens, researchers in the United States of America (USA) and Canada found molecular evidence that the parasitic hookworms (Ancylostoma caninum) in pet dogs across the USA are becoming increasingly resistant to benzimidazole, a broad-spectrum anthelmintic drug used for infection control.

22 Mar 2023

Why are colon cancer rates in young people rising?

In a recent perspective article published in the journal Science, researchers at the Young-Onset Colorectal Cancer Center of Dana-Farber Cancer Institute emphasized that a better understanding of the etiology of early-onset colorectal cancer (EOCRC) is crucial to managing its increasing incidence worldwide

21 Mar 2023

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

A recent Nature Signal Transduction and Targeted Therapy journal study demonstrated the potential antiviral activity of a new Mpro inhibitor (SY110) against SARS-CoV-2 Omicron and its sublineages.

21 Mar 2023

Snapping at new biotech breakthroughs with Gator Pro

In this interview, we speak to Subodh Nimkar, Marketing Director at Gator Bio, about their latest technology, Gator Pro which allows for fast, reliable, and high-quality data.

From Gator Bio, Inc. 21 Mar 2023

INTEGRA Biosciences acquires Miroculus to accelerate genomics

INTEGRA Biosciences is delighted to announce that it has acquired Miroculus, a biotechnology specialist focused on developing hands-off automation solutions for next generation sequencing (NGS) protocols.

From INTEGRA Biosciences 20 Mar 2023

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

More than twelve billion doses of mRNA vaccines have been administered globally since the start of the COVID pandemic, saving millions of lives. But RNA-based therapies for other diseases have so far proven more challenging to develop.

20 Mar 2023

Anti-Omicron antibodies are induced by hypermutation with ancestral BNT162b2 COVID vaccine

Scientists from the Republic of Korea have analyzed B-cell receptor repertoires induced by an mRNA-based coronavirus disease 2019 (COVID-19) vaccine and found that somatic hypermutations in B-cell receptor heavy chain are responsible for broadening its specificity for unexposed antigens.

16 Mar 2023

A novel pan-sarbecovirus vaccine candidate neutralizes Omicron BQ.1.1 and XBB subvariants

Researchers provide evidence that a novel vaccine candidate robustly neutralized SARS-CoV-2 Omicron subvariants BQ.1.1 and XBB.

16 Mar 2023

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).

16 Mar 2023

Albumedix and Heartseed announce Recombumin® as a critical excipient in the manufacture of Heartseed's HS-001 investigational cell therapy as its first in-human trial commences

Albumedix Ltd, Nottingham, United Kingdom, now part of the global life science group Sartorius, and Heartseed Inc ('Heartseed'), Tokyo, Japan, Tuesday 14th March 2023, announce that Recombumin® is a critical component of Heartseed's HS-001, an investigational cardiac remuscularization cell therapy which has commenced first in human dosing.

From Albumedix Ltd. 16 Mar 2023

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.

16 Mar 2023

New genetic animal model may inform potential therapeutic options for Down syndrome

National Institutes of Health researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be more similar to the changes seen in humans.

14 Mar 2023

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

13 Mar 2023

Diabetes and tooth loss contribute to faster cognitive decline in older adults

Having both diabetes and tooth loss contributes to worse cognitive function and faster cognitive decline in older adults, according to a new study published in a special issue of the Journal of Dental Research focused on aging and oral health.

13 Mar 2023

New initiative aims to improve employee well-being and advance health equity in the workplace

Health inequities can be detrimental to employees' emotional, psychological and physical health and place a significant economic burden on employers.

13 Mar 2023

New discoveries made regarding autism onset in mouse models

Although autism is a common neurodevelopmental disorder, the multiple factors behind its onset are still not fully understood.

10 Mar 2023

Individuals with autosomal and X-linked recessive deficiency of IRAK-4 and MyD88 are more susceptible to developing hypoxemic COVID-19 pneumonia

Researchers identified that individuals with a deficiency of myeloid differentiation primary response 88 (MyD88) and interleukin-1 receptor-associated kinase 4 (IRAK-4) due to an autosomal recessive condition were highly susceptible to developing hypoxemic coronavirus disease 2019 (COVID-19) pneumonia when infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Mar 2023

Next Generation News and Research

Reinfections with Omicron VOCs occur more frequently and over shorter intervals

Menin protein protects against aging and cognitive decline

Monovalent vs. bivalent vaccines – Which is more effective against SARS-CoV-2?

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

Why are colon cancer rates in young people rising?

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

Snapping at new biotech breakthroughs with Gator Pro

INTEGRA Biosciences acquires Miroculus to accelerate genomics

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

Anti-Omicron antibodies are induced by hypermutation with ancestral BNT162b2 COVID vaccine

A novel pan-sarbecovirus vaccine candidate neutralizes Omicron BQ.1.1 and XBB subvariants

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

Albumedix and Heartseed announce Recombumin® as a critical excipient in the manufacture of Heartseed's HS-001 investigational cell therapy as its first in-human trial commences

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

New genetic animal model may inform potential therapeutic options for Down syndrome

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Diabetes and tooth loss contribute to faster cognitive decline in older adults

New initiative aims to improve employee well-being and advance health equity in the workplace

New discoveries made regarding autism onset in mouse models

Individuals with autosomal and X-linked recessive deficiency of IRAK-4 and MyD88 are more susceptible to developing hypoxemic COVID-19 pneumonia

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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