Severe Acute Respiratory News and Research

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Primary vaccinations and boosters effective in reducing COVID-19 severity during Delta and Omicron predominance

In a new study, researchers analyzed COVID-19 vaccination and surveillance data to understand the effect of primary vaccinations, boosters, and prior SARS-CoV-2 infections on severe COVID-19 outcomes and subsequent infections.

29 Sep 2022

What are the differences in transmissibility between novel and emerging SARS-CoV-2 variants?

In a new study, researchers compared the transmissibility of novel and emerging SARS-CoV-2 variants.

29 Sep 2022

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Researchers explored the SARS-CoV-2 genome using high-throughput genome sequencing to provide novel insights into how the novel SARS-CoV-2 Omicron BA.2.3.7 variant enters and spreads among the otherwise naïve Taiwanese population.

29 Sep 2022

Study examines the incidence of severe COVID-19 in fully vaccinated and boosted high-risk populations

In new research, scientists studied a cohort of patients at the U.S Veterans Health Administration facilities to determine the incidence of severe COVID-19 outcomes among individuals with primary and booster doses of any combination of BNT162b2, mRNA-1273, and Ad26.COV2.S vaccines.

29 Sep 2022

Study suggests B-cell responses to booster vaccines are impeded by recent SARS-CoV-2 infection

Researchers investigated whether the time of booster vaccination relative to SARS-CoV-2 infection is a crucial determinant of the elicited immune response; in particular, the antibody and B-cell responses.

29 Sep 2022

Exploring remdesivir resistance in COVID-19-infected transplant recipients

In a new study, researchers assessed the remdesivir resistance developed in coronavirus disease 2019 (COVID-19)-infected transplant recipients.

29 Sep 2022

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

Researchers explored SARS-CoV-2 variants of concern/interest (VOC/VOI) kinetics and variations among non-hospitalized acute COVID-19 patients.

29 Sep 2022

Smartphone-based assessment of long COVID symptomatology and risk factors

Researchers quantified the features and risk factors of post-acute COVID-19 syndrome or long COVID based on the integration of survey (active) data and passive [mobile health (mHealth) wearable device] data.

29 Sep 2022

Significant humoral immune evasion contributes to the emergence and rapid spread of Arg346-mutated BA.4 and BA.5 sublineages

=Researchers measured the neutralizing titers of plasma samples against the SARS-CoV-2 new variant of concern Omicron's sub-variants BA.4 and BA.5 with arginine (Arg)346 mutations.

29 Sep 2022

Study aims to understand how SARS-CoV-2 affects the brain long-term

Researchers formulate a method to identify the molecular and systemic factors linking COVID-19 to short- and long-term neurologic illness.

28 Sep 2022

What is the role of N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 spike maturation?

A new study showed that SARS-CoV-2 Spike N-glycosylation patterns, intracellular lectins, and the associated molecular chaperones play crucial roles in the viral-host-cell invasion and function.

28 Sep 2022

COVID-19 cases, hospitalizations, and fatalities prevented by SARS-CoV-2 vaccination within the first 6 months after the vaccine became available

Researchers assessed the effect of SARS-CoV-2 vaccination in the US.

28 Sep 2022

mRNA boosters associated with decreased odds of hospitalization compared with the mRNA vaccine primary series alone

Researchers assessed the chances of COVID-19 hospitalization after three versus two mRNA vaccine doses.

28 Sep 2022

Researchers computationally design immunogens to elicit antibodies against different SARS-CoV-2 variants

A recent study designed immunogens to induce antibodies against SARS-CoV-2 variants.

28 Sep 2022

Can the gut be an alternative route for SARS-CoV-2 entry?

Researchers reviewed the gut pathophysiology of SARS-CoV-2 infection.

28 Sep 2022

Study finds dimethyl fumarate was not associated with an improvement in clinical outcomes in adults hospitalized with COVID-19

Researchers evaluated the efficacy of the anti-inflammatory drug dimethyl fumarate in treating COVID-19 as part of an early phase, randomized, controlled assessment trial in the UK.

28 Sep 2022

Q-LAAD: a dynamic, cost-effective rapid antigen test for detection of SARS-CoV-2

Researchers developed a high-throughput, rapid antigen SARS-CoV-2 spike protein detection test using allonamers, a new type of aptamers that carry out allosteric regulation instead of catalytic activity.

28 Sep 2022

Wastewater epidemiology can guide local clinical decisions on circulating viruses

The findings of a new study posted to the medRxiv* preprint server depicted that wastewater-based epidemiology (WBE) can provide information on the circulating respiratory viruses in a community. As well as saving time and money, this method may assist in appropriate clinical decision-making, behavior modification, and public health interventions.

28 Sep 2022

Food, vaccines, bacteria, and viruses may all prime our immune system to attack SARS-CoV-2

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic, primarily causes mild to moderate upper-respiratory tract illness. However, some individuals with COVID-19 develop severe infections and require hospital admission.

27 Sep 2022

How the gut microbiome could affect COVID-19 severity

Researchers review the potential role of the gut microbiome in determining severe COVID-19.

27 Sep 2022

Severe Acute Respiratory News and Research

Primary vaccinations and boosters effective in reducing COVID-19 severity during Delta and Omicron predominance

What are the differences in transmissibility between novel and emerging SARS-CoV-2 variants?

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Study examines the incidence of severe COVID-19 in fully vaccinated and boosted high-risk populations

Study suggests B-cell responses to booster vaccines are impeded by recent SARS-CoV-2 infection

Exploring remdesivir resistance in COVID-19-infected transplant recipients

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

Smartphone-based assessment of long COVID symptomatology and risk factors

Significant humoral immune evasion contributes to the emergence and rapid spread of Arg346-mutated BA.4 and BA.5 sublineages

Study aims to understand how SARS-CoV-2 affects the brain long-term

What is the role of N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 spike maturation?

COVID-19 cases, hospitalizations, and fatalities prevented by SARS-CoV-2 vaccination within the first 6 months after the vaccine became available

mRNA boosters associated with decreased odds of hospitalization compared with the mRNA vaccine primary series alone

Researchers computationally design immunogens to elicit antibodies against different SARS-CoV-2 variants

Can the gut be an alternative route for SARS-CoV-2 entry?

Study finds dimethyl fumarate was not associated with an improvement in clinical outcomes in adults hospitalized with COVID-19

Q-LAAD: a dynamic, cost-effective rapid antigen test for detection of SARS-CoV-2

Wastewater epidemiology can guide local clinical decisions on circulating viruses

Food, vaccines, bacteria, and viruses may all prime our immune system to attack SARS-CoV-2

How the gut microbiome could affect COVID-19 severity

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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