Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Lab grown, self-renewing muscle stem cells can repair muscle tissue damage in mice

In proof-of-concept experiments, Johns Hopkins Medicine scientists say they have successfully cultivated human muscle stem cells capable of renewing themselves and repairing muscle tissue damage in mice, potentially advancing efforts to treat muscle injuries and muscle-wasting disorders in people.

20 Apr 2022

Cells’ exosomes can be effective vehicles for delivering cancer treatments to tumors

A new study published in Cancer Medicine indicates that exosomes, or small bubbles that transport molecules from one cell to another, can be effective vehicles for delivering cancer treatments to tumors.

20 Apr 2022

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Northwestern Medicine investigators have discovered a novel signaling pathway activated by interferons, a group of immune system proteins, that suppresses the anti-tumor response of interferons in patients with a particular type of blood cancer, according to findings published in Nature Communications.

19 Apr 2022

Scientists precisely define the ‘identity card’ of pancreatic endocrine cells

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.

19 Apr 2022

Injectable hybrid inorganic nanoscaffold-templated stem cell assembly for cartilage repair

This study led by Prof. Qiuyu Zhang (Northwestern Polytechnical University), Prof. Ki-Bum Lee (Rutgers University), and Prof. Liang Kong (School of Stomatology, The Fourth Military Medical University).

19 Apr 2022

Better understanding of hydrocephalus could lead to improved treatments

Hydrocephalus, or "water on the brain," occurs when the cerebral ventricles - four interconnected cavities of the brain that are filled with cerebrospinal fluid - become enlarged, but its cause is unknown in many cases.

18 Apr 2022

A comprehensive rule book for the design of safe and efficient therapeutic cells

Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer.

15 Apr 2022

Regulation of alternative splicing goes haywire in cells of a newly formed embryo

Alternative splicing is a fundamental biological process that allows cells to make many different types of mRNAs and proteins from a limited number of genes. For many animals, including humans, it is a feature that is essential for the development of complex cells such as muscles or neurons.

13 Apr 2022

Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients

Acute lymphoblastic leukemia (ALL) cells from patients whose cancers did not respond to CD19-targeted CAR T therapy had gene regulation signatures that could potentially facilitate treatment resistance, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

13 Apr 2022

Bioprinting for bone repair enhanced with two growth factor encoding genes

Given enough time and energy, the body will heal, but when doctors or engineers intervene, the processes do not always proceed as planned because chemicals that control and facilitate the healing process are missing.

13 Apr 2022

Research using kidney organoids may lead to new targets to help prevent or treat CKD

To a certain extent, kidneys have the capacity to repair themselves after being injured, but a switch can occur from such intrinsic repair to incomplete repair that leads to irreversible damage and chronic kidney disease (CKD).

12 Apr 2022

City of Hope's late-breaking clinical trial data to be presented at AACR

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, will present late-breaking and clinical trial findings at this year's American Association for Cancer Research Annual Meeting, which begins today.

8 Apr 2022

Stem Cells News and Research

Further Reading

Lab grown, self-renewing muscle stem cells can repair muscle tissue damage in mice

Cells’ exosomes can be effective vehicles for delivering cancer treatments to tumors

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Scientists precisely define the ‘identity card’ of pancreatic endocrine cells

Injectable hybrid inorganic nanoscaffold-templated stem cell assembly for cartilage repair

Better understanding of hydrocephalus could lead to improved treatments

A comprehensive rule book for the design of safe and efficient therapeutic cells

Regulation of alternative splicing goes haywire in cells of a newly formed embryo

Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients

Bioprinting for bone repair enhanced with two growth factor encoding genes

Research using kidney organoids may lead to new targets to help prevent or treat CKD

City of Hope's late-breaking clinical trial data to be presented at AACR

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Researchers develop new method to ‘time jump’ skin cells by 30 years

Primordial germ cell-like cells generated from rat stem cells enable the birth of normal offspring

New platform for studying how the immune system responds to hepatitis C

Curcumin released from magnetic hydrogels promotes the secretion of vascular endothelial growth factor

Insights into the pathophysiology of NeuroCOVID

Yale researchers identify accelerated genetic aging in breast tissue adjacent to tumors

Virginia Tech researcher awarded $1.9 million grant to study about mitophagy

Event guide: Supply Chain & Logistics for Cell & Gene Therapy eBook

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