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Sirion Therapeutics sNDA for Durezol to treat uveitis accepted for FDA review

Sirion Therapeutics, Inc. announced today that its supplemental New Drug Application (sNDA) submitted to the U.S. Food and Drug Administration (FDA) seeking market approval of Durezol(TM) (difluprednate ophthalmic emulsion) 0.05% to treat endogenous anterior uveitis has been accepted for review.

16 Mar 2009

Testosterone doping tests in sport ignore ethnic differences in hormone activity

Current steroid (testosterone) doping tests should be scrapped for international sport, because they ignore vital ethnic differences in hormone activity, suggests research published ahead of print in the British Journal of Sports Medicine.

11 Mar 2009

Rituximab may be effective in treating membranous nephropathy

Current treatments for membranous nephropathy are limited to steroids, calcineurin inhibitors, and chemotherapeutic agents, all of which have significant side effects.

11 Mar 2009

European Commission and US FDA approve intravenous formulation of temozolomide

Schering-Plough Corporation (NYSE:SGP) today announced that the European Commission and the US FDA both approved the intravenous (IV) formulation of temozolomide as an alternative to the already approved oral form of the drug.

5 Mar 2009

Protein found linking stress and depression

Stress, the ever-present threat to health and happy living, is tough on the brain. If the strain goes on too long, it can lead to debilitating psychological problems.

25 Feb 2009

Steroids ineffective in young children with wheeze

New research involving medical experts at The University of Nottingham has found that steroid tablets do not reduce the symptoms of virus-induced wheezing in pre-school children.

23 Feb 2009

Asthma drugs need to be maintained for continued benefit

Children whose asthma improved while taking steroid drugs for several years did not see those improvements continue after stopping the drugs, new results from a comprehensive childhood asthma study show.

18 Feb 2009

New approaches to prevent transplant rejection

To prevent the rejection of newly transplanted organs and cells, patients must take medicines that weaken their entire immune systems.

15 Feb 2009

Long-term use of inhaled corticosteroid drugs increases risk of pneumonia for COPD patients

Newly published research out of Wake Forest University School of Medicine finds that a popular class of anti-inflammatory inhalers significantly increases the risk of pneumonia in patients with Chronic Obstructive Pulmonary Disease (COPD).

9 Feb 2009

Volunteers needed for hydrocortisone in treatment resistant depression research

Can hydrocortisone, a drug which affects the body's stress system, help people with depression who do not respond to current treatments?

5 Feb 2009

Pregnancy-related hormonal changes linked to increased risk of restless legs syndrome

A study in the Feb. 1 issue of the journal Sleep shows that the elevation in estradiol levels that occurs during pregnancy is more pronounced in pregnant women with restless legs syndrome (RLS) than in controls.

2 Feb 2009

Study shows no standardized approach to epidural steroid injections for back pain

Today at the American Academy of Pain Medicine's 25th Annual Meeting, researchers from University of California at San Diego report that no standardized practices exist for administering an epidural steroid injection for back pain. Researchers looked at many factors including: which steroids were given, the amount of steroid used, and whether or not a local anesthetic was mixed with the steroid.

29 Jan 2009

Inhaled corticosteroids reduces severity of asthma attacks in preschoolers

The largest study of its kind on preschoolers has demonstrated that preventive treatment with high doses of inhaled corticosteroids is effective in reducing the severity and duration of asthma attacks triggered by colds.

23 Jan 2009

Oral steroids ineffective treatment for wheezing in children

A new study from Barts and The London School of Medicine and Dentistry has found that a common treatment for wheezing in preschool children is no more effective than a placebo.

21 Jan 2009

Pre-emptive treatment helped curtail skin toxicity with Panitumumab

With a pre-emptive, prophylactic skin regimen, patients who receive panitumumab for treatment of metastatic colorectal cancer may be able to avoid some of the skin-associated toxicities, according to data presented at the 2009 American Society of Clinical Oncology Gastrointestinal Cancers Symposium in San Francisco.

19 Jan 2009

Nitric oxide monitoring does not help most children with asthma

The level of nitric oxide (NO) in an asthmatic's exhaled breath can portend worsening asthma symptoms, and may even signify an imminent attack linked to underlying airway inflammation.

7 Jan 2009

Man dies from flesh-eating disease

A rare flesh-eating disease has claimed the life of a man in Britain. The 60 year old man Tony Williamson died days after a flesh-eating disease spread through his body from a small cut on the inside of his right arm.

28 Dec 2008

New research points to possible treatment for Lou Gehrig's disease

There are many ways to die, but amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease must be one of the worst.

10 Dec 2008

FDA grants compassionate case for use of novel wet age-related macular degeneration treatment

NeoVista, Inc., announced today that the U.S. Food and Drug Administration (FDA) had approved the company's "compassionate case" waiver to utilize its novel wet age-related macular degeneration (AMD) treatment on a patient with an advanced form of the disease who did not meet criteria for inclusion into current NeoVista investigational treatment protocols.

10 Dec 2008

Rosiglitazone shows potential for treating focal segmental glomerulosclerosis

The antidiabetes drug rosiglitazone may have the potential to protect kidney function in patients with a condition called focal segmental glomerulosclerosis (FSGS), according to a study appearing in the January 2009 issue of the Clinical Journal of the American Society Nephrology (CJASN).

10 Dec 2008