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Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Researchers evaluated plasma and nasal antibody titers responses induced by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vaccinations among United Kingdom (UK) residents.

23 Dec 2022

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

In order to treat patients with diabetes in the best possible way it is necessary to understand the disease mechanism. MODY type 3 (MODY3) is a monogenic hereditary form of diabetes, that is caused by a genetic defect in the HNF1A gene.

22 Dec 2022

EKF launches handheld veterinary lactate analyzer

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From EKF Diagnostics 22 Dec 2022

Recapitulating early stages of the human body plan in a dish

Although Michelangelo's masterpiece David captured the magnificence of the human body - how this exquisite body plan is exactly established during human development has puzzled scientists for more than a century.

21 Dec 2022

What is the impact of cholesterol on SARS-CoV-2 Spike protein-mediated membrane fusion?

Researchers assessed the impact of ceramide (CER) and cholesterol (CHOL) on membrane fusion mediated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

20 Dec 2022

Non-invasive artificial intelligence approach for IVF embryo selection

An artificial intelligence algorithm can determine non-invasively, with about 70 percent accuracy, if an in vitro fertilized embryo has a normal or abnormal number of chromosomes, according to a new study from researchers at Weill Cornell Medicine.

20 Dec 2022

Smart molecular glue ensures the nucleus is correctly positioned for cell division

Researchers from Paul Scherrer Institute PSI and ETH Zurich have discovered how proteins in the cell can form tiny liquid droplets that act as a smart molecular glue.

19 Dec 2022

New chemical compound shows promise to reverse effects of potentially deadly drugs

Drug overdoses in the United States have risen sharply in the last two decades. Nearly 92,000 people died from overdoses of illegal drugs and prescription opioids in 2020 - more than five times the number of deaths in the year 2000 - and synthetic opioids like fentanyl are one of the main culprits.

16 Dec 2022

Is bottled water really safer?

A new study looked at over 500 contaminants and indicators of microbial activity in 30 brands of bottled water and found some evidence that this supposition might be unfounded.

16 Dec 2022

mRNA vaccine methodologies: Production, value and spectrometer use

To be decided by the editor

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 16 Dec 2022

Activated vitamin D3 inhibits arsenic-mediated carcinogenesis in certain skin cells, research shows

According to recent estimates, over 140 million people from 50 countries regularly get exposed to arsenic through drinking water.

16 Dec 2022

Sheep milk could be an inexpensive source of therapeutic polyclonal SARS-CoV-2 neutralizing antibodies

Researchers used sheep, a ruminant mammal, to obtain polyclonal immunoglobulins (IgGs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Dec 2022

Exercise has many benefits even for people with advanced cancer

It is well-known exercise has many benefits, but new Edith Cowan University (ECU) research has revealed just how critically important it can be – even for people with advanced cancer.

15 Dec 2022

Research reveals that a viral toxin may contribute to the severity of COVID-19

Researchers determine whether the SARS-CoV-2 spike protein influences endothelial and epithelial barrier dysfunction and vascular leakage.

14 Dec 2022

Intranasal recombinant MVA-based vaccines effective against SARS-CoV-2 variants in mice

Researchers construct a recombinant host-range restricted vaccinia virus Ankara (rMVAs) expressing the spike proteins of several SARS-CoV-2 variants.

11 Dec 2022

Researchers design novel compounds with potential as drug treatments for COVID-19

The ongoing COVID-19 pandemic, caused by the SARS-CoV-2 virus, has been devastating the entire world. While the vaccination program is advancing, drug treatments for COVID-19 are still highly important for those who become infected.

9 Dec 2022

What is the association between farnesoid X receptor inhibition and protection against COVID-19?

Researchers assessed the association between farnesoid X receptor (FXR) inhibition and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

9 Dec 2022

Researchers develop transgenic mice with the FRET biosensor for in vivo observation of necroptosis

Necroptosis is a form of regulated cell death (RCD) similar to apoptosis, the most commonly studied type of RCD. In contrast to apoptosis, plasma membrane rupture in necroptotic cells occurs at early time points.

9 Dec 2022

Microbiomes in female reproductive tract linked to pregnancy following use of ART

Specific microbial profiles are associated with better conception rates from assisted reproductive technology.

9 Dec 2022

New spatial cell atlas of the developing human lung identifies 144 cell states

The developing human lung has been mapped in unprecedented detail, identifying 144 cell states in the early stages of life, and uncovering new links between developmental cells and lung cancer.

8 Dec 2022

in vitro News and Research

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

EKF launches handheld veterinary lactate analyzer

Recapitulating early stages of the human body plan in a dish

What is the impact of cholesterol on SARS-CoV-2 Spike protein-mediated membrane fusion?

Non-invasive artificial intelligence approach for IVF embryo selection

Smart molecular glue ensures the nucleus is correctly positioned for cell division

New chemical compound shows promise to reverse effects of potentially deadly drugs

Is bottled water really safer?

mRNA vaccine methodologies: Production, value and spectrometer use

Activated vitamin D3 inhibits arsenic-mediated carcinogenesis in certain skin cells, research shows

Sheep milk could be an inexpensive source of therapeutic polyclonal SARS-CoV-2 neutralizing antibodies

Exercise has many benefits even for people with advanced cancer

Research reveals that a viral toxin may contribute to the severity of COVID-19

Intranasal recombinant MVA-based vaccines effective against SARS-CoV-2 variants in mice

Researchers design novel compounds with potential as drug treatments for COVID-19

What is the association between farnesoid X receptor inhibition and protection against COVID-19?

Researchers develop transgenic mice with the FRET biosensor for in vivo observation of necroptosis

Microbiomes in female reproductive tract linked to pregnancy following use of ART

New spatial cell atlas of the developing human lung identifies 144 cell states

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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