Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Toxin produced by E. coli bacteria also has nondiarrheal effects on the digestive tract

For people in wealthy countries, diarrhea is usually nothing more than an uncomfortable inconvenience for a few days. But for a poor child in a developing country, repeated bouts of diarrhea can lead to serious health consequences such as malnutrition, stunted growth and cognitive deficits.

9 Dec 2020

Study provides a detailed understanding of the interplay between obesity and cancer

Obesity has been linked to increased risk for over a dozen different types of cancer, as well as worse prognosis and survival.

9 Dec 2020

Researchers identify new therapeutic target to treat patients with type 1 diabetes

Researchers at the University of Utah School of Medicine have identified a new therapeutic target to treat patients with type 1 diabetes.

9 Dec 2020

UCI researchers develop noninvasive, at-home saliva test to detect COVID-19

Researchers in the Henry Samueli School of Engineering at the University of California, Irvine announced promising results in the development of a noninvasive at-home antigen test to detect the spike of SARS-CoV-2 proteins in saliva.

9 Dec 2020

Scientists shed light on how neurons form long-term memories

On a late summer day in 1953, a young man who would soon be known as patient H.M. underwent experimental surgery. In an attempt to treat his debilitating seizures, a surgeon removed portions of his brain, including part of a structure called the hippocampus. The seizures stopped.

9 Dec 2020

New consortium aims to understand principles underlying the formation of coronaviruses

The University of California, Riverside, is the recipient of a 2021 UC Multicampus Research Programs and Initiatives, or MRPI, award allowing the campus to put together a UC Coronavirus Assembly Research Consortium.

9 Dec 2020

New data shows abemaciclib continues to benefit high-risk, HR+, HER2-, early-stage breast cancer patients

Extended follow-up data from the phase III monarchE trial showed that adding the cyclin-dependent kinase (CDK) inhibitor abemaciclib (Verzenio) to standard adjuvant endocrine therapy continued to improve invasive disease-free survival (IDFS) among patients with high-risk, node-positive, early-stage, HR-positive, HER2-negative breast cancer, according to data presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11.

9 Dec 2020

Different SARS-CoV-2 neutralization assays are reliable and concordant for antibody monitoring

A recent study by US researchers, currently available on the medRxiv preprint server, evaluated several cell-based assays that are under validation for determining correlates of protection in individuals with symptomatic coronavirus disease (COVID-19) and vaccine studies – and demonstrated their high concordance with both live and pseudotyped virions.

9 Dec 2020

Measuring a tau fragment in plasma can help predict future cognitive decline in elderly people

Today, a clinician can order a blood test to check a patient's cholesterol or hemoglobin A1c levels -- biomarkers that help predict an individual's risk of cardiovascular disease or diabetes, respectively. But despite decades of advances in the understanding of Alzheimer's disease (AD), a blood test for predicting its risk remains elusive.

9 Dec 2020

The effects of cigarette smoke and COPD on SARS-CoV-2 infection

Researchers have revealed some of the effects of cigarette smoke and chronic obstructive pulmonary disease (COPD) on SARS-CoV-2 infection.

9 Dec 2020

UofL receives DoD funding to develop a nasal spray for preventing COVID-19

The University of Louisville has received funding from the U.S. Department of Defense (DoD) to develop a nasal spray to prevent serious viral respiratory infections such as COVID-19 using Q-Griffithsin, a drug compound developed and co-owned by UofL.

9 Dec 2020

Mice study identifies action mechanism of a promising drug against Alzheimer's disease

A study conducted on mice published in the journal Geroscience has identified the action mechanism of a promising compound against Alzheimer's disease, developed by the team of Medical Chemistry and Pharmacology at the University of Barcelona.

9 Dec 2020

Evolutionary gene mutation unique to humans may be to blame for risk of advanced cancers

Compared to chimpanzees, our closest evolutionary cousins, humans are particularly prone to developing advanced carcinomas -- the type of tumors that include prostate, breast, lung and colorectal cancers -- even in the absence of known risk factors, such as genetic predisposition or tobacco use.

9 Dec 2020

Study reveals new biomarker for amyotrophic lateral sclerosis

ALS is a fatal neurodegenerative disease causing a rapid loss of motor function, which usually results in a serious condition with early death within a few years.

9 Dec 2020

Repair protein may prevent damage to healthy cells during cancer therapy

A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

9 Dec 2020

Study reveals human-specific link between advanced carcinomas and a unique gene

Humans are more prone to develop carcinomas compared with our closest evolutionary cousins, the great apes.

9 Dec 2020

Predicting SARS-CoV-2 protein sequences

SARS-CoV-2, the causative agent of COVID-19, consists of an assembly of proteins that determine its infectious and immunological behavior.

9 Dec 2020

Head injuries and long sleep deprivation can affect neurogenerative processes

Scientists from the School of Biomedicine of Far Eastern Federal University (FEFU) with colleagues from Italy, Spain, Romania, and Sweden suggest a way to protect the brain and minimize neurodegenerative processes after concussion head injuries in the presence of extensive previous sleep deprivation.

9 Dec 2020

Interim results show Oxford COVID-19 vaccine protects against symptomatic disease

First full results from interim analysis confirm that the Oxford COVID-19 vaccine (AZD1222) has an acceptable safety profile and is efficacious against symptomatic COVID-19 disease, with no hospitalizations or severe disease reported in the COVID-19 vaccine group so far.

9 Dec 2020

Reductive stress promotes protein aggregation in neuroblastoma cells, impairs neurogenesis

Cells require a balance among oxidation-reduction reactions, or redox homeostasis. Loss of that balance to create oxidative stress is often associated with neurodegeneration. Less is known about how loss of that balance at the other end of the spectrum -- reductive stress, or RS -- may affect neurons.

8 Dec 2020

Protein News and Research

Further Reading

Toxin produced by E. coli bacteria also has nondiarrheal effects on the digestive tract

Study provides a detailed understanding of the interplay between obesity and cancer

Researchers identify new therapeutic target to treat patients with type 1 diabetes

UCI researchers develop noninvasive, at-home saliva test to detect COVID-19

Scientists shed light on how neurons form long-term memories

New consortium aims to understand principles underlying the formation of coronaviruses

New data shows abemaciclib continues to benefit high-risk, HR+, HER2-, early-stage breast cancer patients

Different SARS-CoV-2 neutralization assays are reliable and concordant for antibody monitoring

Measuring a tau fragment in plasma can help predict future cognitive decline in elderly people

The effects of cigarette smoke and COPD on SARS-CoV-2 infection

UofL receives DoD funding to develop a nasal spray for preventing COVID-19

Mice study identifies action mechanism of a promising drug against Alzheimer's disease

Evolutionary gene mutation unique to humans may be to blame for risk of advanced cancers

Study reveals new biomarker for amyotrophic lateral sclerosis

Repair protein may prevent damage to healthy cells during cancer therapy

Study reveals human-specific link between advanced carcinomas and a unique gene

Predicting SARS-CoV-2 protein sequences

Head injuries and long sleep deprivation can affect neurogenerative processes

Interim results show Oxford COVID-19 vaccine protects against symptomatic disease

Reductive stress promotes protein aggregation in neuroblastoma cells, impairs neurogenesis

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