Inflammation News and Research

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Limited decision-making ability of individual cells is bolstered in masses

Researchers from Johns Hopkins have quantified the number of possible decisions that an individual cell can make after receiving a cue from its environment, and surprisingly, it's only two.

14 Oct 2011

InnaVirVax announces Phase I/IIa clinical trial authorization for its VAC-3S HIV vaccine

InnaVirVax, a biopharmaceutical company dedicated to the development of therapeutic and diagnostic solutions in pathologies associated with immune dysregulation, declared today that it has obtained authorization from the French drug agency (AFSSAPS) to start a Phase I/IIa clinical study of its therapeutic vaccine VAC-3S for the treatment of HIV infections. This authorization intervenes only two years and half after the launching of InnaVirVax’s activities.

14 Oct 2011

UofL researchers to develop treatments for chlorine-induced lung injuries

Gary Hoyle, PhD, professor, University of Louisville School of Public Health and Information Sciences, will build on his research to develop an effective medical treatment to counteract chlorine-induced lung injuries caused by chemical accidents or acts of terrorism.

13 Oct 2011

U of U researchers receive NIH grant to uncover viral cause of MS

A team of investigators from the University of Utah has received a two-year, $275,000 grant from the National Institutes of Health (NIH) to fund novel research that may help to uncover a viral cause for the most acute and severe form of multiple sclerosis.

13 Oct 2011

Narrow band imaging an equally effective alternative to chromoendoscopy for dysplasia

A new study from Spain finds that narrow band imaging appears to be a less time-consuming and equally effective alternative to chromoendoscopy for the detection of dysplasia (abnormal growths) in patients with long-standing inflammatory bowel disease.

13 Oct 2011

UA researchers to study immune response to implanted sensors

A University of Arkansas professor and her colleagues will receive $1.3 million over four years to study the immune response to implanted sensors, such as glucose sensors for diabetics, in hopes of prolonging the life of these important monitoring systems.

13 Oct 2011

Three key steps to prevent asthma attacks in children during winter

For most people, the word "autumn" conjures up images of honey crisp apples, pumpkin patches and Halloween. But for many pediatricians, fall also means more patients with asthma flare-ups.

13 Oct 2011

Affymetrix launches Axiom Pan-African Array

Affymetrix, Inc. today announced at the ICHG/ASHG annual conference in Montreal, the worldwide launch of the Axiom Genome-Wide Pan-African Array, the first commercial product to maximize genomic coverage of both common and rare alleles in populations of African ancestry, including West African, East African, and African American.

13 Oct 2011

Tantalizing glimmers about roles of CCR2 gene, Th17 cell and a missing monocyte

An estimated 1.3 million people in the United States suffer from rheumatoid arthritis. The causes behind this chronic disease — which can exhibit itself as pain, swelling, stiffness, deformation, and loss of function in the joints — have eluded scientists for centuries. A new study by UNC researchers offers tantalizing glimmers about the roles of a gene called CCR2, an immune system cell called Th17 cell, and a missing monocyte.

11 Oct 2011

Omeros initiates OMS302 Phase 3 trial in intra-ocular lens replacement surgery

Omeros Corporation today announced that the first patients have been treated in the Company's Phase 3 clinical program evaluating OMS302 in intra-ocular lens replacement surgery.

11 Oct 2011

New siRNA treatment reduces damaging inflammation in animals models of several disorders

Massachusetts General Hospital (MGH) researchers - along with collaborators from Massachusetts Institute of Technology (MIT) and Alnylam Pharmaceuticals - have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions.

10 Oct 2011

First successful quantification of membrane lipids in a living cell

Could controlling cell-membrane fat play a key role in turning off disease? Researchers at the University of Illinois at Chicago think so, and a biosensor they've created that measures membrane lipid levels may open up new pathways to disease treatment.

10 Oct 2011

Researchers identify cellular pathway to potentially block disease-inducing inflammation

Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases.

10 Oct 2011

First COX-2-targeted PET imaging agent for use in animal models of inflammation, cancer

A series of novel imaging agents could make it possible to "see" tumors in their earliest stages, before they turn deadly.

10 Oct 2011

NCKU research team discovers potential target to treat osteoporosis

A National Cheng Kung University (NCKU) research team has discovered that a protein called interleukin (IL)-20 is a key to treating osteoporosis, a disease that lowers a person's bone density.

7 Oct 2011

Neutrophils inhibit restenosis in patients with atherosclerosis after stent implantation

A research team led by LMU's Professor Christian Weber has now shown that a specific cell type called neutrophils, and molecules that they secrete, inhibit this life-threatening complication - which is observed in up to one-third of all stent implantations.

7 Oct 2011

New NIH grant to continue exploration of Fusobacterium nucleatum-associated Beta-Defensin Inducer

Research from Case Western Reserve University School of Dental Medicine to study an isolated agent from common oral bacteria may hold the answer as to how human beta defensins (HBDs)-nature's way of keeping oral microbes from entering the body and wreaking havoc with our health-can be used to create new treatments to block bacteria from entering through the epithelial linings on and in the body.

4 Oct 2011

Lung immune cells orchestrate the body's repair response following flu infection

There's more than one way to mop up after a flu infection. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania report in Nature Immunology that a previously unrecognized population of lung immune cells orchestrate the body's repair response following flu infection.

4 Oct 2011

Creabilis receives $20 million in Series B funding

Creabilis SA, a clinical stage European biotechnology company addressing unmet medical needs in dermatology, inflammation and pain, has raised €15 million ($20 million) in a Series B funding round led by Abbott Biotech Ventures.

4 Oct 2011

Combination therapy improves outcomes for liver cancer patients: Study

A combination of an oral drug, called sorafenib, and a method for injecting microbeads of chemotherapy directly into tumors has been proven safe for liver cancer patients and may improve outcomes for those who have these fast-growing, deadly tumors whose numbers are on the rise in the U.S.

1 Oct 2011

Inflammation News and Research

Limited decision-making ability of individual cells is bolstered in masses

InnaVirVax announces Phase I/IIa clinical trial authorization for its VAC-3S HIV vaccine

UofL researchers to develop treatments for chlorine-induced lung injuries

U of U researchers receive NIH grant to uncover viral cause of MS

Narrow band imaging an equally effective alternative to chromoendoscopy for dysplasia

UA researchers to study immune response to implanted sensors

Three key steps to prevent asthma attacks in children during winter

Affymetrix launches Axiom Pan-African Array

Tantalizing glimmers about roles of CCR2 gene, Th17 cell and a missing monocyte

Omeros initiates OMS302 Phase 3 trial in intra-ocular lens replacement surgery

New siRNA treatment reduces damaging inflammation in animals models of several disorders

First successful quantification of membrane lipids in a living cell

Researchers identify cellular pathway to potentially block disease-inducing inflammation

First COX-2-targeted PET imaging agent for use in animal models of inflammation, cancer

NCKU research team discovers potential target to treat osteoporosis

Neutrophils inhibit restenosis in patients with atherosclerosis after stent implantation

New NIH grant to continue exploration of Fusobacterium nucleatum-associated Beta-Defensin Inducer

Lung immune cells orchestrate the body's repair response following flu infection

Creabilis receives $20 million in Series B funding

Combination therapy improves outcomes for liver cancer patients: Study

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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