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Certain occupations do increase risk of breast cancer

Is there a link between the risk of breast cancer and the working environment? A study published in BioMed Central's open access journal Environmental Health provides further evidence on this previously neglected research topic, confirming that certain occupations do pose a higher risk of breast cancer than others, particularly those that expose the worker to potential carcinogens and endocrine disrupters.

19 Nov 2012

Four New York students named National Finalists in Siemens Competition

Months of dedication and hard work in science, technology, engineering and mathematics (STEM) paid off tonight for four students named National Finalists in the Siemens Competition in Math, Science & Technology, the nation's premier research competition.

19 Nov 2012

Positive results from Genentech Avastin plus temozolomide Phase III study on glioblastoma

Genentech, a member of the Roche Group, today announced results from the positive Phase III AVAglio study. The study showed Avastin (bevacizumab) in combination with radiation and temozolomide chemotherapy reduced the risk of cancer worsening or death (progression-free survival; PFS) by 36 percent compared to radiation and temozolomide chemotherapy plus placebo>th Annual Meeting of the Society for Neuro-Oncology in Washington, D.C.

19 Nov 2012

College of American Pathologists accredits NCH’s Biopathology Center

Biorepositories are highly complex research facilities with expert staff to process, store, characterize and secure biological specimens and their corresponding clinical information.

17 Nov 2012

Researchers develop safe, feasible and robust co-culture system for hESC expansion

Researchers in Taiwan have developed a "safe, feasible and robust co-culture system" supplied by human umbilical cord mensenchymal stem cells (HUCMSCs) to feed the sustained culture used for human embryonic stem cell (hESC) expansion prior to cell transplantation.

17 Nov 2012

Combination of Abraxane and gemcitabine improves survival of patients with pancreatic cancer

A new cancer drug combination demonstrated significant improvement in overall survival of late-stage pancreatic cancer patients compared to those receiving standard treatment, according to results of a Phase III clinical trial led by physicians from Scottsdale Healthcare's Virginia G. Cancer Center Clinical Trials, a partnership with the Translational Genomics Research Institute (TGen).

17 Nov 2012

Scientists identify cell growth pathway that is unusually active in gliomas

Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.

17 Nov 2012

GW researcher gets NCI grant to study behavior of parasitic worm in bile duct cancer

Paul Brindley, Ph.D., professor of microbiology, immunology, and tropical medicine at the George Washington University School of Medicine and Health Sciences, was the recipient of a $1.7 million grant from the National Cancer Institute to study the behavior of a parasitic worm, rampant in Southeast Asia, known to cause infections that contribute to liver cancer.

16 Nov 2012

Study shows boost in access to screening for breast and cervical cancer

A study by researchers at the George Washington University School of Public Health and Health Services indicates that full implementation of the Affordable Care Act would expand health insurance coverage for more low-income women, enabling more than a million women to obtain potentially life-saving screening for breast and cervical cancer.

16 Nov 2012

Transcription factor expression aids stage I lung cancer prognosis

Expression of thyroid transcription factor-1 is an independent predictor for recurrence of stage I lung adenocarcinoma and allows intermediate-grade tumors to be split into two prognostic subsets, scientists have found.

16 Nov 2012

New insights into how MSCs ‘traffic’ from the circulation into tissues

Mesenchymal stem cells (MSCs), are a newly emerging cellular therapy being tested in approximately 250 clinical trials worldwide to help repair damaged tissues, such as injured heart muscle following a heart attack. The problem is that when culture-expanded MSCs are injected into the circulation, they have trouble gaining access to the inflamed tissues-exactly where their help is needed.

16 Nov 2012

New AAN book for people with primary and metastatic brain tumors

It is estimated that every 30 minutes, someone is diagnosed with brain cancer. Published in conjunction with the American Academy of Neurology as part of the Neurology Now Books series, NAVIGATING LIFE WITH A BRAIN TUMOR provides readily accessible information and encouragement for the thousands of people living with primary and metastatic brain tumors.

16 Nov 2012

Promising new minimally toxic approach to treat solid tumors with radiation

A promising new approach to treating solid tumors with radiation was highly efficacious and minimally toxic to healthy tissue in a mouse model of cancer, according to data published in Cancer Research, a journal of the American Association for Cancer Research.

15 Nov 2012

RainDance's ThunderStorm System for targeted sequencing selected by UCL Cancer Institute

RainDance Technologies, Inc., the Digital Biology Company, today announced that the University College London (UCL) Cancer Institute has adopted its ThunderStorm System as a centralized platform for the validation of genomic and epigenomic targets from clinical and non-clinical studies, including follow-ups for genome-wide and epigenome-wide association studies (GWAS and EWAS), as well as stratified cancer medicine and basic research.

15 Nov 2012

Study on effect of glucose on cancer growth in mice

An animal study conducted by researchers at Georgetown Lombardi Comprehensive Cancer Center raises questions about the consequences of diet - specifically glucose, the plant-based sugar that fuels cell life - on increased activity of an oncogene that drives tumor growth.

15 Nov 2012

Viruses to treat metastatic cancers

There exists a "type" of cancer that is common yet rarely discussed—metastatic cancer, or cancer that has spread from the part of the body where it originated (the primary tumor) to another (such as lungs, bones or liver). Although much research is being done to combat primary tumors, there still exists a crucial need to find a treatment that can be effective against metastatic cancer, or "mets." Could a virus be the answer that finally beats the mets?

15 Nov 2012

New gene delivery vehicle opens route to the heart of cells in solid tumors

There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart of the target.

15 Nov 2012

Scientists eliminate metastasis in laboratory experiments

In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 (mda-9)/syntenin. More than 1 million cases of skin cancer are diagnosed each year in the U.S., and melanoma is the deadliest form.

15 Nov 2012

Medulloblastomas that arise from different cell types might require personalized treatments

Cancers arise when a normal cell acquires a mutation in a gene that regulates cellular growth or survival. But the particular cell this mutation happens in-the cell of origin-can have an enormous impact on the behavior of the tumor, and on the strategies used to treat it.

14 Nov 2012

Lung cancer stem cells can be isolated and grown in preclinical models

A University of Cincinnati (UC) Cancer Institute lung cancer research team reports that lung cancer stem cells can be isolated-and then grown-in a preclinical model, offering a new avenue for investigating immunotherapy treatment options that specifically target stem cells.

14 Nov 2012