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Obesity strongly associated with clonal hematopoiesis of indeterminate potential

Indiana University School of Medicine researchers studying clonal hematopoiesis of indeterminate potential (CHIP), a blood condition that may increase the risk of blood cancer, discovered that obesity was strongly associated with the condition.

16 May 2023

Advancing Precision Medicine in Argentina, Brazil and Chile – BGI Update

BGI Genomics recently participated in a mission business to South America in April 2023.

From BGI Genomics 16 May 2023

Michael Milken wants to speed up cures

Years ago, a top chemical biologist pondered ditching his cancer research to take a more lucrative commission growing healthier apples. Michael Milken stopped him.

16 May 2023

Does obstructive sleep apnea increase the risk of post-acute sequelae of SARS-CoV-2?

Research paper examines the potential link between obstructive sleep apnea (OSA) and Post-Acute Sequelae of SARS-CoV-2 (PASC), the long-term effects of COVID-19. It investigates whether OSA increases the risk of more severe PASC outcomes.

15 May 2023

Research sheds light on potential application of cyclodextrin derivatives in drug-supersaturated formulations

In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body.

15 May 2023

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

A new international study published in Nature Medicine and presented as a late-breaking abstract at the American Association of Neurological Surgeons annual conference, shows great promise for patients with glioblastoma.

15 May 2023

Obesity undermines COVID-19 vaccines

Researchers examine the impact of obesity on COVID-19 outcomes and the effectiveness of vaccines in individuals with obesity. Using data from Scotland, the study explores the relationship between body mass index (BMI) and hospitalization/mortality due to COVID-19.

15 May 2023

Non-coding genetic molecules may hold promise for warning of esophageal cancer

Irregularities in the body's genetic coding to make proteins are linked to cancerous tumors. But most genetic material contains elements whose function isn't clear.

15 May 2023

Can machine learning improve myocardial infarction diagnosis?

Researchers discuss a novel clinical decision support system based on machine learning models to predict an individual’s probability of myocardial infarction.

15 May 2023

Henry Ford Health cardiologists perform new coronary bypass procedure that replicates an old operation

Henry Ford Health Interventional cardiologists William O'Neill, M.D., and Khaldoon Alaswad, M.D., took a page out of the medical history books by performing a new coronary bypass procedure replicated from one not used in decades to treat a patient living with crippling angina - a severe symptom of coronary artery disease.

15 May 2023

HER2-TPMC proves to be a reasonable alternative for HER2-positive cancer chemotherapeutics

Announcing a new article publication for BIO Integration journal. Antibody-drug conjugates (ADCs) have the following advantages: target specificity; wide therapeutic index; and prolonged circulation half-life.

15 May 2023

Nominations open now for BIAL Award in Biomedicine

The third edition of the BIAL Foundation's international award, the BIAL Award in Biomedicine, is now underway, with nominations open until 30 June.

15 May 2023

UArizona Health Sciences researchers seek to improve opioid therapy while decreasing its side effects

University of Arizona Health Sciences researchers are taking the foot off the brake in their quest to improve opioid therapy while decreasing its side effects.

15 May 2023

Cyclical estrogen/anti-estrogen therapy could be a promising strategy to treat metastatic ER+ breast cancer

Advanced or metastatic estrogen receptor-positive (ER+) breast cancer is commonly treated with drugs that block the estrogen receptor.

15 May 2023

Integrated proteomics approach identifies the contents of p62 bodies in detail

Our body functioning is delicately balanced between the synthesis and breakdown of various cellular components.

15 May 2023

Study shows two distinct types of cerebellar neurons differentially regulate motor and social behaviors

The cerebellum, a major part of the hindbrain in all vertebrates, is important for motor coordination, language acquisition, and regulating social and emotional behaviors.

15 May 2023

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Newly identified genetic variant provides protection from Alzheimer's disease

A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment.

15 May 2023

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto.

15 May 2023

Study sheds light on the importance of a subset of microglial cells in cognition and memory

A new study sheds light on the importance of microglia, the immune cells of the brain, in cognition and memory.

15 May 2023

Medicine News and Research

Obesity strongly associated with clonal hematopoiesis of indeterminate potential

Advancing Precision Medicine in Argentina, Brazil and Chile – BGI Update

Michael Milken wants to speed up cures

Does obstructive sleep apnea increase the risk of post-acute sequelae of SARS-CoV-2?

Research sheds light on potential application of cyclodextrin derivatives in drug-supersaturated formulations

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

Obesity undermines COVID-19 vaccines

Non-coding genetic molecules may hold promise for warning of esophageal cancer

Can machine learning improve myocardial infarction diagnosis?

Henry Ford Health cardiologists perform new coronary bypass procedure that replicates an old operation

HER2-TPMC proves to be a reasonable alternative for HER2-positive cancer chemotherapeutics

Nominations open now for BIAL Award in Biomedicine

UArizona Health Sciences researchers seek to improve opioid therapy while decreasing its side effects

Cyclical estrogen/anti-estrogen therapy could be a promising strategy to treat metastatic ER+ breast cancer

Integrated proteomics approach identifies the contents of p62 bodies in detail

Study shows two distinct types of cerebellar neurons differentially regulate motor and social behaviors

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Newly identified genetic variant provides protection from Alzheimer's disease

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Study sheds light on the importance of a subset of microglial cells in cognition and memory

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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