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Sacubitril/valsartan shows benefit over enalapril in heart failure caused by Chagas disease

In patients with heart failure (HF) caused by Chagas disease, sacubitril/valsartan was superior to enalapril for the composite primary endpoint, predominantly driven by a significant reduction in N-terminal pro-B-type natriuretic peptide (NT-proBNP), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

At CDC, worries mount that agency has taken anti-science turn

Public health and access to lifesaving vaccines are on the line in a high-stakes leadership battle at the Centers for Disease Control and Prevention.

3 Sep 2025

Roasted Arabica coffee hides powerful antidiabetic molecules

Three novel coffee diterpene esters, caffaldehydes A, B, and C, were discovered in Arabica beans, showcasing significant alpha-glucosidase inhibitory activity.

3 Sep 2025

How raspberry leaf tea reduces insulin surges from table sugar

Trial shows that raspberry leaf tea blunts sucrose-induced glucose and insulin surges, offering a natural strategy for moderating blood sugar without the side effects of pharmaceutical enzyme inhibitors.

2 Sep 2025

Social Security praises its new chatbot. Ex-officials say it was tested but shelved under Biden.

John McGing couldn't reach a human. That might be business-as-usual in this economy, but it wasn't business; he had called the Social Security Administration, where the questions often aren't generic and the callers tend to be older, disabled, or otherwise vulnerable Americans.

2 Sep 2025

ESC and EAS release new dyslipidaemia guidelines

The European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS) have just published the new international recommendations for managing dyslipidaemias. They were presented at the Annual Cardiology Congress held in Madrid from August 29th to September 1st, 2025.

2 Sep 2025

Compounds show significant inhibitory effects on α-glucosidase

Three of the compounds demonstrated significant inhibitory effects on α-glucosidase, a key enzyme in carbohydrate digestion. The findings could pave the way for new functional food ingredients targeting type 2 diabetes.

2 Sep 2025

Heart failure hospitalization occurs earlier in Black and Hispanic adults than white patients

Black adults in the U.S. are first hospitalized for heart failure nearly 14 years earlier than white adults, reports a Northwestern Medicine study that analyzed data from more than 42,000 patients across hundreds of hospitals nationwide.

1 Sep 2025

How a Mediterranean diet helps women manage menopausal symptoms

A cross-sectional study of 149 postmenopausal women found that greater adherence to a modified Mediterranean diet was linked to lower odds of moderate to severe hot flashes and sexual symptoms. While psychological and physical domains showed no significant association, the results support further evaluation of diet as a non-hormonal strategy for menopausal care.

1 Sep 2025

Baxdrostat offers hope for millions with difficult-to-control high blood pressure

A new treatment has been shown to significantly lower blood pressure in people whose levels stay dangerously high, despite taking several existing medicines, according to the results of a Phase III clinical trial led by a UCL Professor.

1 Sep 2025

How plant compounds could target Alzheimer’s disease from multiple angles

This review highlights how dietary polyphenols modulate Alzheimer’s disease biology through antioxidant, anti-inflammatory, and multi-target mechanisms, supported by in-silico docking analyses. Despite promise, challenges in bioavailability and brain delivery remain key hurdles to clinical translation.

31 Aug 2025

Ultra-processed foods affect sperm quality and metabolism even without extra calories

A controlled crossover trial in Cell Metabolism found that ultra-processed foods increase weight, fat mass, LDL:HDL cholesterol, and alter reproductive hormones in men, with some effects independent of calorie load. These diets also showed trends toward reduced sperm motility, shifts in pollutants, and transient inflammatory responses, highlighting risks beyond excess calories.

31 Aug 2025

Male and female bovine embryos show distinct development paths

Cornell researchers have uncovered the genetic triggers that cause male and female bovine embryos to develop differently, as early as seven to eight days after fertilization.

29 Aug 2025

New study reveals how child neglect impacts critical brain pathways

When we think of child abuse, physical violence or emotional cruelty often comes to mind first. However, the most common form of maltreatment is actually much quieter: neglect.

29 Aug 2025

Predictable music phrases found to regulate blood pressure

A new study has found that blood pressure synchronises to predictable phrase structures in music. Blood pressure was more affected by loudness than tempo and was more strongly influenced by phrase structures that were more predictable.

29 Aug 2025

What are the benefits of chewing gum beyond oral health?

Chewing gum offers health benefits beyond oral care, enhancing performance and recovery, but research gaps for children and seniors need addressing.

29 Aug 2025

Stress in mothers causes eczema in newborn mice through immune cell changes

Maternal prenatal stress in mice disrupts fetal mast cell programming, triggering eczema-like skin inflammation and heightened sensitivity after birth. The findings reveal how corticosterone-driven immune and neuronal changes in utero may set the stage for pediatric eczema risk.

28 Aug 2025

Food delivery riders could help speed defibrillator access in cardiac arrest emergencies

Inspired by an urgent need to improve timely defibrillation for out-of-hospital cardiac arrests (OHCA) in dense urban settings, a team of investigators developed a simulation that explored the potential of leveraging an existing food delivery network in Taipei City, Taiwan, to help address this challenge.

28 Aug 2025

Ultra-processed foods harm reproductive and metabolic health

Over the past 50 years, rates of obesity and type-2 diabetes have soared, while sperm quality has plummeted. Driving these changes could be the increasing popularity of ultra-processed foods, which have been linked to a range of poor health outcomes.

28 Aug 2025

Illinois researchers highlight most effective nutritional approaches for GI distress in cancer care

Many modern cancer treatments are highly effective at reducing or eliminating tumors, but they can also cause severe gastrointestinal symptoms that impact patients' quality of life or lead to discontinuation of treatment.

28 Aug 2025