Lung Disease News and Research

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Enrollment complete in Boehringer Ingelheim’s nintedanib phase III studies for IPF

Boehringer Ingelheim Pharmaceuticals, Inc. announced that clinical trial enrollment has completed for two phase III studies evaluating the safety and efficacy of nintedanib (BIBF 1120), an investigational compound, in patients with idiopathic pulmonary fibrosis (IPF), being studied at a twice-daily oral dose.

27 Sep 2012

Chronic respiratory disease treatments: an interview with Dr Sven Jan-Anders Karlsson, CEO of Verona Pharma

There are many different chronic respiratory diseases. Verona Pharma is mainly focused on two diseases: asthma and COPD. Asthma is a very common disease and unfortunately it has been increasing in prevalence in developed countries. This is the same with COPD; however, there may be different reasons for this.

25 Sep 2012

Even partially matched bone marrow transplants can eliminate sickle cell disease in some patients

In a preliminary clinical trial, investigators at Johns Hopkins have shown that even partially matched bone marrow transplants can eliminate sickle cell disease in some patients, ridding them of painful and debilitating symptoms and the need for a lifetime of pain medications and blood transfusions.

24 Sep 2012

Partially-matched bone marrow transplants can eliminate sickle cell disease in some patients

In a preliminary clinical trial, investigators at Johns Hopkins have shown that even partially-matched bone marrow transplants can eliminate sickle cell disease in some patients, ridding them of painful and debilitating symptoms, and the need for a lifetime of pain medications and blood transfusions. The researchers say the use of such marrow could potentially help make bone marrow transplants accessible to a majority of sickle cell patients who need them.

21 Sep 2012

Secondhand smoke continues to take a grievous toll on nonsmokers

Secondhand smoke is accountable for 42,000 deaths annually to nonsmokers in the United States, including nearly 900 infants, according to a new UCSF study.

21 Sep 2012

Partially-matched bone marrow transplants can eliminate sickle cell disease in some patients

21 Sep 2012

Thalidomide effective in treating disabling cough among people with idiopathic pulmonary fibrosis

In the first clinical trial to demonstrate an effective treatment for constant, disabling cough among people with idiopathic pulmonary fibrosis (IPF), researchers at the Johns Hopkins University School of Medicine found that taking thalidomide significantly reduced the cough and improved quality of life.

18 Sep 2012

Two abnormalities associated with cystic fibrosis-related diabetes

A new University of Iowa study suggests there are two root causes of a type of diabetes associated with cystic fibrosis (CF). The findings, which already have sparked a clinical trial, may guide development of new treatments or even help prevent diabetes in patients with CF.

18 Sep 2012

Drug-resistant tuberculosis: an interview with Sven Hoffner

In contrast to drug-susceptible tuberculosis, which can be cured with available drug therapies, drug-resistant, and especially multi-drug resistant, tuberculosis is much more difficult to cure and it takes a much longer time for patients to become non-infectious.

17 Sep 2012

Smoking history 'no bar to successful lung donation'

Although lung transplantation from donors with a positive smoking history is associated with worse outcomes than with lungs from non-smoking donors, survival is still better than remaining on the waiting list, say UK researchers.

13 Sep 2012

CT shows promise in predicting COPD exacerbation risk

Measurement of the pulmonary artery-to-aorta ratio can predict the risk for exacerbations in patients with chronic obstructive pulmonary disease, particularly those that require hospitalization, say the authors of a US study.

11 Sep 2012

Partial pressure measures could be used in neonates after surgery

End tidal carbon dioxide and transcutaneous carbon dioxide could be useful to monitor partial pressure of arterial CO2 in neonates after surgery, a study shows.

10 Sep 2012

New oral antiseptic spray effective in killing 99.9% of infectious airborne germs

University Hospitals Case Medical Center clinical researchers will present findings about a one-two punch to prevent colds and flu in San Francisco at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) on Sept. 9.

10 Sep 2012

Washington Post examines India's efforts against TB amid fears of drug resistance

The Washington Post examines how the "discovery of an almost untreatable form of tuberculosis [TB] in India has set off alarm bells around the world and helped spur a dramatic expansion of government efforts to battle the killer lung disease."

7 Sep 2012

Interleukin-18 plays a key role in inflammation

The naturally occurring cytokine interleukin-18, or IL-18, plays a key role in inflammation and has been implicated in serious inflammatory diseases for which the prognosis is poor and there are currently limited treatment options.

7 Sep 2012

NSA launches new Faces of Stroke mini-campaign

National Stroke Association has launched a new Faces of Stroke(SM) mini-campaign designed to educate about the connection between stroke and Afib, a type of irregular heartbeat that increases risk of stroke by five times.

6 Sep 2012

First global benchmarks for assessing lung function across entire life span

New research has established the first global benchmarks for assessing lung function across the entire life span. The lung growth charts will help healthcare professionals better understand lung disease progression and help raise awareness of lung disease, which is the world's leading cause of death.

5 Sep 2012

CT scan appears to predict risk of chronic obstructive pulmonary disease exacerbations

The respective size of two major arteries, visible on a simple computed tomography, or CT, scan, is a strong predictor of the risk of exacerbation of chronic obstructive pulmonary disease, according to new research from the University of Alabama at Birmingham published online Sept. 3, 2012, in the New England Journal of Medicine.

3 Sep 2012

SPIRIVA to mark 10th anniversary with European Respiratory Society Congress

Coinciding with the annual European Respiratory Society Congress, ERS 2012, SPIRIVA (tiotropium), the first once-daily long-acting inhaled anticholinergic maintenance treatment for patients with Chronic Obstructive Pulmonary Disease (COPD) will mark its 10th anniversary since launch.

3 Sep 2012

Positive results from Elevation Pharmaceuticals’ EP-101 Phase 2b study on COPD

Elevation Pharmaceuticals, Inc. today presented positive efficacy and safety results from the GOLDEN-1 study – a Phase 2b study evaluating EP-101 in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) – at the annual meeting of the European Respiratory Society in Vienna, Austria.

3 Sep 2012

Lung Disease News and Research

Enrollment complete in Boehringer Ingelheim’s nintedanib phase III studies for IPF

Chronic respiratory disease treatments: an interview with Dr Sven Jan-Anders Karlsson, CEO of Verona Pharma

Even partially matched bone marrow transplants can eliminate sickle cell disease in some patients

Partially-matched bone marrow transplants can eliminate sickle cell disease in some patients

Secondhand smoke continues to take a grievous toll on nonsmokers

Partially-matched bone marrow transplants can eliminate sickle cell disease in some patients

Thalidomide effective in treating disabling cough among people with idiopathic pulmonary fibrosis

Two abnormalities associated with cystic fibrosis-related diabetes

Drug-resistant tuberculosis: an interview with Sven Hoffner

Smoking history 'no bar to successful lung donation'

CT shows promise in predicting COPD exacerbation risk

Partial pressure measures could be used in neonates after surgery

New oral antiseptic spray effective in killing 99.9% of infectious airborne germs

Washington Post examines India's efforts against TB amid fears of drug resistance

Interleukin-18 plays a key role in inflammation

NSA launches new Faces of Stroke mini-campaign

First global benchmarks for assessing lung function across entire life span

CT scan appears to predict risk of chronic obstructive pulmonary disease exacerbations

SPIRIVA to mark 10th anniversary with European Respiratory Society Congress

Positive results from Elevation Pharmaceuticals’ EP-101 Phase 2b study on COPD

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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